NERVOUS SYSTEM/ENDOCRINE SYSTEM MODULE TEST SUBJECT:

PHYSIOLOGY SECOND YEAR MBBS, CONVENTIONAL, 2021, KMDC,

DATED 06-MAY-2021
NERVOUS SYSTEM/ENDOCRINE SYSTEM MODULE TEST SUBJECT:
PHYSIOLOGY SECOND YEAR MBBS, CONVENTIONAL, 2021, KMDC,
DATED 06-MAY-2021
Instructions:
1- Paper Start Time: 10:00AM
2- Total Marks: 47
3-Time Limit 47 Minutes
3- Passing Marks 50%
4- Choose the best option by clicking the circle
5- Attempt all Questions (No Negative Marking)
Note: Submit your assessment must before 10:47AM. Paper will not be
submitted after the prescribe time.

Following is not a stress homone;

Adrenaline
Glucocorticoides
Noradrenaline
Parathormone

Which hormone from the anterior pituitary gland regulates the release
of corticosteroid hormones from the adrenal cortex?
TSH
ACTH
FSH
LH

Which of the following hormones are produced and secreted by the

adrenal medulla?
T4 (thyroxine) and T3 (triiodothyronine)
Adrenaline and noradrenaline
Insulin and glucagon
Calcitonin and parathyroid hormone (PTH)

Cholecalceferol (Vitamin D3) is formed in ;

Kidneys
Skin
Liver
Bones

Increased muscle spindle sensitivity to stretch secondary to increased

Ay efferentdischarge can occur with:
Anxiety
Hypertonia
Skin stimulation on the ipsilateral skin
All of above

Following not included as basal functional structures of limbic system;

Amygdala
Hypothalamus
Mammary body
Raphe nuclei

G-proteins (guanine nucleotide-binding proteins) are molecules

involved in the transmission of hormonal signals from outside a cell to
the interior by means of a process called:
Signal transduction
Signal conduction
Signal targeting
Local signalling

Destruction of cerebellum leads to the following EXCEPT:

Ataxia
Hypertonia
Dysmetria
Dysdiadochokinesia
Autonomic nervous system can increase the heart rate in 3-5 seconds,
upto;
145 b/min
190 b/min
200 b/min
80 b/min

Cerebellum receives input from the following sites EXCEPT:

Labyrinth & vestibular nuclei
Somatosensory pathways
Visual impulses from tectum
Motor cortex

Complication of spinal cord transection includes:

Decubitus ulcer
Catabolic state with negative nitrogen balance
Hypercalcemia & renal calculi
All of the above

Hyperthyroidism shows;
Extreme fatigue with sleep.
Extreme fatigue with inability to sleep.
Extreme fatigue with deep sleep.
Extreme fatigue with no change in sleep pattern.

Which type of sensation is most affected in the lesions in sensory cortex

Position & fine touch
Temperature differentiation
Pain
Gross touch

Which of the following statements is TRUE?

Visceral pain tends to be poorly localized & is often referred to distal
sites.
Ischemic muscle tends to be persistently painful until reperfusion
occurs, due to accumulation of metabolic products such as potassium.
Visceral afferents travel along the same pathway as the somatic
sensory afferents in the spino-thalamic tract.
All of the above.

The posterior pituitary gland is sometimes called the neurohypophysis

and it secretes which neurohormones?
Calcitonin and parathyroid hormone (PTH)
Insulin and glucagon
Adrenaline and cortisol
Antidiuretic hormone (ADH) and oxytocin

Sleep does not help;

Neural maturation.
Cognition
Facilitation of learning
Consumption of energy

Cortical representation of somatic sensation lies in:

Central fissure
Pre-central gyrus
Post-central gyrus
Posterior parietal cortex

Thalamus contain relay nuclei for:

Auditory information
Visual information
Somatosensory information
All of the above

During periods of mental activity ,brain waves become;

Asynchronous
Synchronous
High voltage
Low frequency

Which of the following is an example of monosynaptic reflex?

Stretch reflex
Withdrawal reflex
Abdominal reflex
Baroreceptor reflex

Most hormones travel from the gland where they were produced to the
tissues and cells which they act upon:
Along nerve fibres
Via synapses
In the bloodstream
In ducts

Slow pain fibers are all except;

Carried by paleospinothalamic tract
Mostly slow chronic C type
Precisely localized
Secrete substance P
Midbrain responses include the following EXCEPT:
Vestibulo-ocular reflex (righting reflex)
Pupillary reaction
Mass reflex
Vestibular placing reaction

Which of the following statement regarding reticular activating system

is FALSE?
RAS is important for regulation of alertness & consciousness.
RAS is found in the anterior pontine region
RAS is the site of integration of various polysynaptic reflexes
RAS is responsible for regulation of heart rate, blood pressure &
respiratory pattern.

What type of signalling occurs when neurons release chemical signal

molecules which influence the activity and behaviour of neighbouring
neurons?
Autocrine
Synaptic
Paracrine
Endocrine
Which of the following cell types is NOT found in the pancreas?
Acinar cells
Alpha cells
Beta cells
Kappa cells

Following increase insulin secretion;

Decreased blood glucose.
Somatostatin.
Fasting
Glucagon

Most commonly occurring complication due to chronic high plasma

glucose;
Joint pains
Abdominal discomforts
Peripheral neuropathy
Atherosclerosis

The type of glial cells functon as scavenger or brain macrophages;

Oligodendrides.
Microglia
Schwann cells
Astrocytes

Which of the following pairing of parts of cerebellum & its function is

CORRECT?
Spinocerebellum – motor execution
Vestibulocerebellum – balance & eye movement
Cerebrocerebellum – motor planning
All of the above

Many nerve endings of the fibers from the raphe neurons of lower half
of pons secrete;
Hitamine
Serotonin
Adrenaline
Bradyinin

Chief inhibitory neurotransmitter in the basal ganglia is:

Glutamate
GABA
Dopamine
Acetylcholine
Which of the following statements regarding pain sensation
transmission is FALSE?
Fast or I st pain is transmitted by A8 fiber.
Slow or 2nd pain is transmitted by C fiber.
Pain impulses are modified at the dorsal horn by interneurons &
collateral touch fibers.
Principal neurotransmitter of pain is histamine

Which of the following statements regarding muscle spindle is FALSE?

It contains nuclear bag & nuclear chain fibers, which are responsible for
dynamic & static responses respectively.
It is important as a feedback sensor to give information about muscle
length
It has no contractile elements at all
Increased Ay motor efferent discharge to muscle spindle will lead to
increased muscle spindle sensitivity to stretch.

EEG patterns can be affected by the following EXCEPT:

Changes in PaC02
Changes in temperature
Changes in Pa02
Glucocorticoid hormone
Primary Aldosteronism is also called;
Hyperkalemia
Conn’s Syndrome
Hyponatremia
Cushing’s Syndrome

Following gives most accurate diagnosis in hyperthyroidism;

Plasma TSH concentration
Basal metabolic rate
Radioimmunoassey
Free thyroxine concentration

Which hormone is produced in the hours of darkness and encourages

sleep?
Insulin
Renin
Angiotensin
Melatonin

The family of steroid hormones are chemically derived from cholesterol

and include:
Gonadotrophin-releasing hormone (GnRH), growth hormone-releasing
hormone (GHRH) and thyrotropin-releasing hormone (TRH)
Growth hormone (GH) and adrenocorticotrophic hormone (ACTH)
T4 (thyroxine) and T3 (triiodothyronine)
Corticosteroids, sex hormones and vitamin D

Which of the following sleep disorder is associated with REM sleep?

Nocturnal enuresis
Narcolepsy
Night tremors
Sleep walking

Which hormone is primarily responsible for uptake of glucose from

blood by cells?
Insulin
Renin
Angiotensin
Leptin

Inhibits growth hormone secretion;

Decreased blood glucose
Decreased free fatty acids
Exercice
Aging
Duration of spinal shock in human lasts a minimum of :
2 days
I week
2 weeks
1 month

The exocrine cells of the pancreas produce:

Adrenaline
Insulin
Cortisol
Digestive juices

Which of the following comments regarding lateral corticospinal tract is

FALSE?
It contains 80% fiber of the corticospinal pathway.
It decussates at the level of medullary pyramids.
It innervates lateral nuclei in the anterior hom.
It controls axial muscle mainly & so is important for posture regulation

The gland that secretes the hormone that determines the basal rate of
metabolism and normal growth is located:
In the brain
In bones
In front of the trachea
In the pelvis

Chronic spinal patient does not have:

Hyperactive stretch reflex
Flaccid hypotonic bladder
Widely swing blood pressure due to loss of baroreceptor reflex
Loss of vasomotor control resulting in sweating & blanching of skin.