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in our ody, which activate each other and action organ called exocrine
are glands, e.g
work as asystem called endocrine system. mucous gland, sweat gland, etc.
Hormone
Heterocrine Gland The gland that works as
It is a nical
chemical
regulator.
It is a specific
messenger, exocrine as well as endocrine is called heterocrine
which releases directly into the bloodstream and gland. Pancreas is the example of such type of
raved elsewhere in the body up to the target organs. gland. It is because its exocrine portion secretes
ot pancreatic juice which helps in digestion of food.
General Properties of Hormones The endocrine portion of pancreas secretes a
Hormones are specitic in function, act on target
hormone called insulin, which control the blood
organs, tissue and cells away from the source.
sugar level.
They are secreted in minute quantities.
The study of hormones and endocrine system is
Their effects are long-lasting and slow in action. called endocrinology. Thomas Addison is called
Hormones stimulate the tissue activities. the father of endocrinology.
They control growth and development. Endocrine Glands of Human Body
They control metabolism. The major endocrine glands of human body are
They synthesise, store and utilise substances, e.g. shown below in Fig. 10.1.
tor
glucose. Hypothalamus
They are non-nutritive in nature. Pituitary gland
lark
Their deficiency and excess leads to serious
disorders in the body. Thyroid gland
Chemically they are steroids, proteins, peptides
or amino acids. Pancreas
Adrenal gland
Testis (male)
kretes a useful chemical substance required for a
9y-X Fig. 10.1 The major endocrine glands of human body
particular function within the body is called gland.
Location of Major Endocrine Glands in Human
Body
Adrenal glands are located on the top of each
kidney and fitting like a cap.
Pancreas
P'ancreas is located behind the stomach and
associated with the liver.
Duodenum Islets of Langerhanv
Thyroid gland is associated with neck region Fig. 10.3 Pancreas hans
below larynx.
Pituitary gland is associated with brain attached .Thyroid Gland
to hypothalamus. Thyroid gland the largest
is
situated on either side of endocrin
Adrenal Gland the trachea
The adrenal glands, also called suprarenal glands, windpipe at the lower or
extremity of thehe laryx.
are two, cream-coloured conical glands located on secretes hormones called thyroxin and
the top of each kidney and consists of an inner calcitonin.
central core the adrenal medulla and a n outer part
the adrenal cortex.
Larynx
Right adrenal Left adrenal
gland gland Right lobe -Left lobe
Isthmus Trachea
Fig. 10.4 Thyroid gland in front view
Left kidney
Right kidney Hypersecretion of thyroxin causes
exophthalni
Fig. 10.2 Adrenal glands goitre in adults. Due to this, a
person becoms
Adrenal medulla secretes two hormone overactive and nervous, may lose
weight and ha
adrenaline and nor-adrenaline. Adrenaline is protruding eyeball.
called emergency hormone. Hyposecretion of thyroxin causes hypothyroidim.
Adrenal cortex secretes a number of hormones, If it occurs in infants, the disorder is calli
such as glucocorticoids and mineralocorticoids cretinism.
Hormones of adrenal cortex is involved in the
A severe deficiency or a total lack of thyroxin in
body reactions to stress and to adapt different adults produces a condition known as myxoedenm.
climatic conditions by vasoconstriction and
This causes dry skin and puffiness of the fac
vasodilation.
particularly around the eyes. The tongue becoms
.Pancreas The patient feels sleepy and cold.
Pancreas is a heterocrine gland. The islet of
enlarged.
lack of iodine in the diet usually cau
A severe
Langerhans is the endocrine part of pancrea_. It's disorder n
a-cells produce glucagon and B-cells produce insulin. simple goitre. The simple goitre is a
sweling
which thyroid gland enlarges, marked by a
oestrogen and progesterone and formation of explained with reference to TSH as follows:
corpus luteum.
Thyroxin is a hormone secreted by thyroid gland,
which helps to regulate metabolism.
Prolactin stimulates the mammary glands for
level falls or
production of milk in mothers. When the blood thyroxin
Growth Hormone (GH) also called somatotropin metabolism significantly reduced, the hypo
and releases TRH
afects growth. Too much secretion of this thalamus detects the change
in response. It
hormone during childhood can cause a person to (thyrotropin-releasing hormone)
become a giant gigantism) and too little travels to pituitary gland and stimulates the
secretion can cause a person to be a dwarf release of TSH (thyroid stimulating hormone), in
release more
(dwarfism). turn causing the thyroid gland to
. Hormone gets transported through blood to the 5. Impulses transmitted electro-chemically thro
target organs. nerve fibre. nrough
6. It is carried out by chemicals called hormones. 6. It is carried out by conduction of nerve imn.
pulses.
Table 10.2 Differences between diabetes mellitus and diabetes insipidus
Diabetes mellitus Diabetes insipidus
1. It is caused due to the high level of blood sugar. 1. Blood sugar is normal.
2. Glucose is excreted in urine. 2. Glucose is not excreted in urine.
3. It is due to the deficiency of insulin. 3. It is caused due to the deticiency of vasopresin
or ADH.
4. Urine output and thirst are comparatively less. 4. Urine output and thirst are excessive.
Bank Biology
ICSE Question
190
,
T a b l e.
103 Summary of mammalian endocrine glands and hormones produced by them
Endocrinegland Hormones secreted Functions Hyposecretion Hypersecretion
1. Adrenal gland
(Suprarenal)
(i) Adrenal ) Mineralocorticosteroids Cushing's
Regulate plasma sodium and Addison's
cortex (aldosterone) potassium concentrations disease syndrome
(i) Glucocorticoids
Regulate carbohydrates, lipid
(cortisol, corticosterone) and protein metabolism
(ii) Sex hormones Stimulate development of
androgen in males and external sex characters both in
oestrogen in females males and females
(Gi) Adrenal Adrenalin Causes stimulation of
medulla
sympathetic division of ANS
during stress.
2. Pancreas (i) Insulin-ß cells Lowers the blood sugar level, Hypoglycemia Diabetes
(Islets of i.e. converts mellitus
glucose to glycogen
Langerhans) Gi) Glucagon-a cells Balance the effect of insulin,
i.e. converts glycogen to
glucose
(ii) Somatostatin-Y cells Inhibits the secretion of
(not in the syllabus) insulin and glucagon
3. Thyroid () Thyroxin Promotes tissue metabolism, Simple goitre, Exophthalmic
growth and differentiation cretinism in goitre
children and
myxoedema
in adults
(ii) Calcitonin Promotes movement of calcium
(not in the syllabus) ions from blood to bones
Pituitary
(i) Anterior (i) Growth hormone Body growh Dwarfism Gigantism in
pituitary (somatotropin; GH) childhood,
acromegaly in
adulthood
(i) Prolactin Promotes lactation
(ii) Adrenocorticotropic Stimulates secretion of Pigmentation
Hormone (ACTH) glucocorticoids from in Addisons
adrenal cortex disease
(iv) Thyroid Stimulating Stimulates thyroxin secretion
Hormone (TSH)
(v) Follicle Stimulating In females, growch of Graafian
Hormone (FSH) follicles and oestrogen secretion
and spermatogenesis in males
(vi) Luteinising Hormone Ovulation, maintenance of
(LH) corpus luteum and secretion of
progesterone in females and
testosterone secretion in males.
(Gi) Posterior ) Vasopressin (ADH) Conservation of body water and Diabetes Elevation of
contraction of blood vessels insipidus arterial blood
pituitary
pressure
(ii) Oxytocin Causes contraction of uterine
muscles during childbirth
Ans. (a) nervous (b) blood (c) pituitary (d) uterus (e) myxoedema
( adrenaline cortex (g) adrenal cortex (h) thyroxin () chemicalon) ) insulin
2. Complete the following sentencesby choosing the correct word from those given in the brackets:
(a) Deficiency of insulin results in (f) Exophthalmic goitre is caused due to the
(diabetes mellitus/diabetes insipidus) of thyroid gland.
Hyperthyroidism/exophthalmic goitre
8. Hypothalamus
9. 7. Gigantism
10. T h y r o x i n
Adrenocorticotropic Hormone (ACTH)
Mutiple Choice Questions
Multiple
organ is
the site of options given below:
Which
glucose to
glycogen 6.
conversion? Deficiency of which hormone during early
(a) Thyroid (b) Pancreas infancy causes cretinism?
(a) Adrenaline (b) Insulin
o )Liver (d) Pituitary
() Oestrogen (d) Thyroxin
Vhich hormone contains iodine? 7. Which of the following symptoms is least
a) Thyroxin (b) Oxytocin likely
to be a
symptom of hypothyroidism?
( Insulin (d) Oestrogen
(a) Mental sluggishness
Vhich organ produces digestive enzymes and
hormones?
(b) Slow reflexes
(a) Pancreas (b) Thyroid (e)Feelingcold
(d) Liver (d) Loss of weight
(c) Pituitary
4Which hormone is responsible for ejecting milk 8. Which organ produces a hormone which
from the mammary glands? stimulates thyroxine production?
a) Oestrogen (b) FSH (a) Adrenal (b) Liver
c) LH (d) Oxytocin () Thyroid (d) Pituitary
5.Pituitary hormones are not involved in thee 9. Which of the following is an effect of insulin?
regulation of which of the following (a) Conversion of glucose to glycogen
(a) Thyroid gland (b) Adrenal cortex (c) Increase in flow of blood to skeletal muscles
Islets of Langerhans (6) Increased water reabsorption in the kidney
d)Ovary (d) Production of sperm cells.
Ans. 1. (c) 2. (a) 3. (a) 4. (d 5. (c) 6. (d) 7. (a) 8. (d) 9. (a)
D. Match the Column.
Match the items in column I with those given in column II.
Column I Column II
1. Acromegaly
(a) Under secretion of adrenal cortex
2. Addison's disease
(b) Under secretion of thyroxin in children
3. Insulin shock
(c) Oversecretion of growth hormones in adults
4. Cretinism
(d) Under secretion of growth hormone
5. Dwarfism
(e) Oversecretion of insulin
Ans. 1.c)
2.(a) 3.(e) 4.(b) 5.(d)
Endoorine System
193
Given in the box set of 18 biological Of these, 14 can be paired into 7 matchine
terms.
E. are a
an example. Identify the six pairs
pairs. Out of the seven pairs, one has been done for you as
Endocrine System
H. Short Answer Questions Type ll Each question
carries 3
Q1. State three characteristics
of hormones. Ans. (a) Thyroid Thyroxin, which mat
Ans. (a) Hormones are
secreted by endocrine gulates bod
metabolism, growth and develon
glands (b) Pancreas Insulin, which evelontrols
opmenm.
glucose level by
(b) They are specific in action and are
secreted in minute glucose into glycogen.
converting the exceblog
quantities.
(c) They are
chemically proteins, biogenic (c) Adrenal medulla
Adrenaline
amines or steroids. increases heartbeat, bloc whi
Q2. Name three organs that are endocrine as well reduces volume of urine. pressure
as exocrine in function. Also name their condition of stress, it raises Durin
endocrine secretions. blood gl
by glycogenolysis.
Ans. Organ Endocrine secretion Q6. Explain the following
1. Pancreas Insulin and glucagon (a) Role of insulin in maintain
2. Testes Testosterone sugar level blo
3. Ovary Oestrogen and progesterone
(b) Acceleration of body growth durin.
Q3. What is the function of somatotropic puberty. ring
hormone? Name the diseases caused due to
the hypersecretion and hyposecretion of this
(c)Regulation of secondary sexual characten
by pituitary gland.
hormone.
Ans. (a) Insulin converts
Ans. The
somatotropic hormone promotes the glucose into
excess
the
calcium and phosphate levels in secretion of anterior pituitary.
For example,
the secretion of the gland which The amount of urine output is under regulation
(b) Name
regulates basal metabolism. called (a). secreted by
of a hormone
Name the mineral element required
for the the (b). lobe of the pituitary gland.
(c)
of the above mentioned hormone. this hormone secretion is reduced, there is an
synthesis
Name the disease caused due under secretion
to increased production of urine. This disorder
(d)
. Sometimes excess glucos
of the above mentioned hormone in children. called (c)
Name the disease caused due to hypersecretion is passed with urine due to hyposecretion o
()
of the above mentioned hormone. another hormone called (d) leading-
5 Marks) [20171 to the cause of a disease called (e).
Mention the exact location of the following:
(5 Marks) [2016
Islets of Langerhans (1 Mark) 120171 9. State the exact location of the following structuic
for the following statement: Thyroid gland (1 Mark) [201
Give biological reason
Some women have facial hair like beard and 10. Given alongside is the outline
moustache. (2 Marks) [2017] of the human body showing
6. Choose the correct answer from cach of the four the important glands:
options given below:
Gigantism and acromegaly are due to
Biology*
200 ICSE Question Bank
marked I 4.
the glands i) A gland which secretes both hormones and
to
Name
(a)
Jame
(b)Name the the hormone secreted by part-2. Give enzymes is the
important function of this hormone. (a) pituitary (b) pancrecas
one
Name the endocrine part of the part (c) thyroid (d) adrenal
numbered 3. (1 Mark) [2013]
the part labelled 1 called the master 17. Expand the following biological abbreviation:
Why is
Why
d)
Which part of the torebrain controls (1 Mark) [2014)
gland? TSH
labelled 1?
thegland 18. Give a technical term for the following:
Name the gland that secretes the emergency
(e) Group of hormones which influence other
hormone. (5 Marks) 2016) endocrine glands to produce hormones.
Give one important function of this hormone. ) Increased blood supply to muscles.
(5 Marks) [200°
ndo 203
19. 1.Thyroxin
2.
Posterior lobe of Regulates
3. basal metabolism pancreatic juice and
endocrine
4. pituitary
Increases reabsorption islets of
Langerhans which part
of water from -insulin and glucagon. crete cont
5. kidneys
7.
B cells of
Tears
pancreas 6. Insulin (d) Ifgiven orally, insulin will be hormones
(lacrimal fluid containing dioe
protein digesting enzymes in ested by ihe
8.
Keeps the clean
lysozyme) Therefore, it is the
eye by washing away injected only into toma
particles and kills germs
dust
() Islets of Langerhans
or the
body.
tomach
9. Adrenaline pancreatic
()Along the posterior margin of islet
10.
Prepares body thesto.
situation for
to meet any emergency
the loop of duodenum.
stomach in
20.
fight or for flight. 28. Category-Hormones of anterior pituitary
Pituitary gland is also known the master gland
as
Odd term-Vasopressin
because it controls the functions of all other 29. (a) 1. Pituitary 2. Thyroid
endocrine glands. 4. Adrenal 5. Ovaryy
3. Pancreas
21. Beta cells
of pancreas produce insulin. (b) Thyroxin
22. Vasopressin hormone Function: It
regulates the basal metaboli
23. (a) the body. lism of
Acromegaly Cretinism () Islets of Langerhans
Abnormal growth Results in retarded
of lower jaw, face, (d) Adrenaline hormone
physical and mental
hand and feet bones. Function: It prepares the
development, short body to fare
hand, feet and
emergency situation of
fight, friphr any
pigeon chest.
flight.
30. False. The pancreas is both exocrine
and
(b)Diabetes mellitus Diabetes insipidus endocrine in function.
Caused due to Caused due to 31. (a) Beta cells of pancreas
undersecretion of undersecretion of 32 (a) Adrenaline (b) Insulin
insulin hormone.
antidiuretic hormone. (c) Glucagon (d) Thyroxin
24. Interstitial cells Leydig cells.
or (e) Thyroxin () Adrenaline
25. The pituitary gland or hypophysis is attaches to
(g) Growth hormone (h) Gonadotrophic
the hypothalamus by a short, slender stalk called hormones
infundibulum. (i) Vasopressin Gi) Adrenaline
26. This is because in hilly regions, the soil is 33. (a) Testis
deficient of iodine rich
compounds. (b) Development of secondary sexual charactes
i) in males
a) Glucagon-Alpha cells
(i) Insulin-Beta cells (c) Adrenaline
(d) Dilation of blood vessels, pupil of eye, etc
(b) G) Glucagon converts stored glycogen to
glucose in the liver when the energy is () Thyroid (f) Thyroxine (gTears
required by the body cells. (h) Cleans the eye from dust and microbes
(ii) Insulin accelerates conversion of excess i) Anterior pituitary
glucose into glycogen. ) Gigantism/Dwarfism secret
both duct gland
(c) Because it acts and an as a 34. False. The alpha cells of the pancreas
endocrine gland. lts duct gland produces
glucagon.
Bank Biology
204 ICSE Question
ASSESS YOURSELF
ne:1 Hour Marks: 30
Langerhans are (c) from beta cells, (d) (c) Name two other conditions that could have
from alpha cells and (e). from resulted due to a similar cause.
delta cells. (d) lodine is required for synthesis of which
4. Explain briefly: (1Mark Each) hormone?
a) Glucose is normally not found in urine. (e) Where is thyroid gland located?
Endoorin 205