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Hormones and typical and atypical sexual development. ( review


lecture/audio is bad)

! The determination of the development of ovaries or testie is dependent on


the SRY Gene (presence causes male gonadal; development) \
o Sexual development can be atypical if partial expression of the Sry
or SOx9 gene results in abnormal development both testies and
ovaries
! Swyer syndrome: A rare disorder characterized by the failure of the sex
glands (testis or ovaries) to develop in XY individual that lack SRY gene
o Classified as a DSD (disorder of sex development)
! If testosterone is absent in development the Wolferman fails to occurs
even though the individual has the XY.
! If the Mullerian inhibitory hormone is not released at the appropriate time,
then the Mullerian ducts will develop despite the chromosomal sex.
! Intersex: An atypical development which results in individuals being born
with ovaries and testis, merged tissue/ separate tissue (ovaries-testies)
o Mosaicism: has both XX and Xy in separate parts/cells of the body

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