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Effect of Amlodipine Versus Benazepril in Treatment of Arteriosclerosis in Patients With Renal Hypertension
Effect of Amlodipine Versus Benazepril in Treatment of Arteriosclerosis in Patients With Renal Hypertension
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ABSTRACT:Obj e cti
ve Toi nv est
igatethee f
fectofa mlodipinev er
susbe nazepr
ilint r
e at
me nt
ofa r
teri
os c
lero s
isinpa ti
e ntswithren alhy pe r
tens
ion.Me thods Oneh undreda nds eventy
fivepa
ti
entswi t
hr e nalh ypert
ens i
oni nourh o spit
a lwerer and
o mlydivide di nt
ot wog r
oup s.Gro upA(n=
94)r eceiveda mlodipi
nef or5~1 0mgo n cead ay,a ndg ro
u pB(n=81)r eceiv
edbe nazeprilf
o r10~
20mgo ncead a
y.Bl o
odp res
sureanda r
terio
scle
rosisindicat
orsi ncludi
ngbr achial
anklepu l
sewa v
e
vel
o ci
ty(b aPWV)a nda n kl
ebrac
h i
ali ndex(ABI )we reme a
suredbe fo
rea nda f
ter8mo nthso fan t
i
hypertensivet hera
py .Re sult
s Theb lo o
dp res
surea f
tertreatme nto fbothg roupss i
gnifi
cantlyde
creasedc ompa r
edwi thbe for
et r
eatmen t(P<0. 05),whi letherewe ren os i
gnif
icantbetwe e
n g
roup
dif
ferencesi nbl oodpr es
s uresbefor
ea nda ft
ertreat
me nt(P>0.0 5).Af t
ertreat
me nt,b aPWVo fB
groupwa ss ign i
fi
ca nt
lylowe r,ABIwa ss i
g nif
ica
ntlyh i
ghert hant hatbe f
oret r
eatment(P<0.05),
butnos i
g ni
fic a
ntdi ff
erenc e
swe refo undi na bor
ei ndicat
orsbe forea nda fte
rtr
eatmenti nA g r
oup s
(P>0. 05).Conc l
usi
on Be na
zeprilha sb ett
ere f
fe
ctint r
e a
tme nto fart
erios
cler
o s
iscause dbyr enal
hypertensiont hana mlodipine.
KEY WORDS:r e nalhypert
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