Document Code No.

CHS/BSN-CURR -RLEFORM-002d
Revision No. Effective Date Page No.
00 02.24.2023 1 of 1

DRUG STUDY
Brand Name: Keflex Generic Name: Cephalexin Drug Classification: Antibiotic, Cephalosphorins

Dosage, Route & Frequency Drug-Drug &

Side Effects Adverse Reactions
Drug Action Drug-Food Indications Contraindications
Recommended Prescribed (By System) (By System)
Interactions
Adults: Bactericidal: Inhibit Warfarin: Cephalexin Respiratory tract Hypersensitivity to the  diarrhea CNS: Headache,
1–4 g/day in divided doses; synthesis of can worsen the risk of infections caused drug or contents of this nausea dizziness, lethargy,
250 mg PO q 6 hr usual bacterial cell wall, bleeding when used by Streptococcus drug; renal failure, renal vomiting paresthesias
dose 500 mg cap 1 cap tid causing cell death. with warfarin.  pneumoniae, group impairment; pregnancy;  rash
PO A beta-hemolytic breastfeeding; urticaria
Pediatric: BCG vaccines: streptococci coagulopathy, vitamin K
GU: Nephrotoxicity
 dyspepsia
25–50 mg/kg/day PO in Antibiotics — deficiency; diabetes abdominal
divided doses including cephalexin Skin and skin mellitus pain
Hematologic: Bone
— may cause the structure dizziness marrow depression
BCG vaccine to be infections caused  headache 
less effective by staphylococcus, Hypersensitivity: Rangin
by lowering the streptococcus g from rash to fever to
immune response.  anaphylaxis; serum
Otitis media caused sickness reaction
Zinc: can lower the by S. pneumoniae,
absorption of Haemophilus
influenzae, Other: Superinfections
cephalexin in the
body, causing it to be streptococcus,
less effective in staphylococcus,
fighting infections Moraxella catarrhalis

Bone infections
caused
by staphylococcus,
Proteus mirabilis

GU infections
caused
by Escherichia coli,
P. mirabilis,
Klebsiella

Responsibilities in the Nursing Process (ADPIE) Responsibilities in the Nursing Process (ADPIE)
Assessment Teaching points:
 History: Penicillin or cephalosporin allergy, pregnancy, or lactation  Take this drug with food. 
 Physical: Renal function tests, respiratory status, skin status; culture and  Report severe diarrhea with blood, pus, or mucus; rash or hives; difficulty
sensitivity tests of infected area breathing; unusual tiredness, fatigue; unusual bleeding or bruising.
 Avoid alcohol while taking cephalexin.
Interventions
 Arrange for culture and sensitivity tests of infection before and during
therapy if infection does not resolve.
 Give drug with meals; arrange for small, frequent meals if GI complications
occur.
 Refrigerate suspension, discard after 14 days.

EVALUATION TOOL:
UNACCEPTABLE
1-7
Only a few of the drugs were listed down; or some drugs were not
listed down; intended indication and mechanism of action of the
given medication/s as well as the side-effects, contraindications and
nursing responsibilities were incorrect and not relevant to the
assigned patient
SATISFACTORY EXCEPTIONAL REMARKS
8-12 13-20
some drugs were not listed down; intended indication and mechanism Listed down all the drugs; intended indication and
of action of the given medication/s as well as the side-effects, mechanism of action of the given medication/s as well as
contraindications and nursing responsibilities were correct and relevant the side-effects, contraindications and nursing
to the assigned patient responsibilities were correct and relevant to the assigned
patient