NAME OF DOSAGE/FRE CLASSIFIC MECHANISM INDICATIONS/ SIDE ADVERSE NURSING RESPONSIBILITIES

DRUG Q/ ATION OF ACTION CONTRAINDICATIONS EFFECTS EFFECTS

ROUTE
/SUPPLIED
Generic Name: 500mg, TID, Therapeutic: Clavulanic acid Indivations: ➢ Erythema CNS: Before:
Co-amoxiclav PO, 1 tab Broad- contains a beta Known or suspected ➢ Dizziness lethargy, ➢ First, always check doctors
spectrum actam ring in its amoxicillin-resistant infections ➢ Convulsi hallucinations, anxiety, order.
antibiotic structure that binds including respiratory tract, skin ons confusion, agitation, ➢ Introduce oneself and ask
in an irreversible and soft tissue, genitourinary, ➢ Exfoliati depression, fatigue, for the patient’s name and
Brand Name: Pharmacologi fashion to beta- and ear, nose and throat ve hyperactivity, birthdate.
Clavulin c: lactamases, infections. Effective against dermatiti insomnia, ➢ Identify or determine history
Beta-lactam preventing them strains of Escherichia coli, s behavioral changes, of drug allergy during
and beta- from inactivating Proteus mirabilis, ➢ Headache seizures (with assessment or interview.
lactamase certain beta-lactam Haemophilus influezae, ➢ Phlebitis high doses) ➢ Keep in mind the five rights
inhibitor antibiotics, with Streptococcus fecalis, at before giving medication.
efficacy in treating Streptococcus pneumonia and injection GI: ➢ pseudomembranous colitis
susceptible gram- some beta-lactase-producing site. nausea, vomiting, may occur, so assess bowel
positive and gram- organisms. ➢ multifor diarrhea, pattern before and during
negative infections. m abdominal pain, treatment.
➢ Toxic stomatitis, glossitis, ➢ Always assess respiratory
Reference: Contraindication: epiderma gastritis, black “hairy” status of the patient prior to
Co- -Caution is warranted when l tongue, furry giving the medication.
amoxiclav:Uses, treating patients on necrolysi tongue, enterocolitis,
Side Effects, hemodialysis or with severe s pseudomembranous During:
Mechanism,Dosage renal impairment with ➢ Vasculiti colitis ➢ Encourage the patient to eat
| DRUGSBANK. creatinine clearance less than s meal before taking the
(2017, August 8). 30 mL/minute. As this GU: medication or tell the patient
https://www.drugsb antibiotic primarily gets vaginitis, nephropathy, that she may take drug food.
anks.com/co- renally excreted, individuals interstitial ➢ Instruct the patient to ensure
amoxiclav/#:~:text with renal disease will need Nephritis they take the full course of
=Mechanism%20O dose adjustments and closer the medicine.
f%20Action%20%3 monitoring.[17] Hematologic:
A%20Co- anemia, ➢ Do not crush the given
amoxiclav%20is%2 -There are no guidelines for thrombocytopenia, medication.
0a%20broad- dosing in hepatic impairment, thrombocytopenic ➢ Instruct to take medicine in
spectrum but extreme caution is purpura, equal dose around the clock
necessary when considering leukopenia, hemolytic to maintain level in the
use in this population. This anemia, blood.
medication is contraindicated ➢ Drink a lot of water.
 in any patient with a prior agranulocytosis, bone
history of amoxicillin or narrow depression, After:
clavulanic acid-induced eosinophilia ➢ Educated that this drug is
hepatic dysfunction.[22] specific for this infection
Hepatic: and should not be used to
-Lastly, use in patients with cholestatic hepatitis self-treat other problems.
previous hypersensitivity ➢ If the patient experiences
reactions to amoxicillin, Respiratory: symptoms of an allergy,
clavulanic acid, or other beta- wheezing
such as a rash, wheezing,
lactam antimicrobials is also
itching, fever, or swelling in
contraindicated. As
amoxicillin is a penicillin the joints, this should be
derivative, there is a high reported.
likelihood of crossover ➢ Report any symptoms of
hypersensitivity in patients pseudomembranous colitis,
with a documented penicillin such as diarrhea, cramps,
allergy. In this population, and blood in the stool.
clinicians should consider
alternative antimicrobial
options.

NAME OF DOSAGE/FRE CLASSIFIC MECHANISM INDICATIONS/ SIDE EFFECTS ADVERSE NURSING RESPONSIBILITIES
DRUG Q/ ATION OF ACTION CONTRAINDICA EFFECTS
ROUTE TIONS
/SUPPLIED
Generic Name: 500mg, BID, Therapeutic: Interferes with Indication: ➢ unusual CNS: Before:
Cefuroxime PO, 1 tab Bactericidal bacterial cell wall Treatment if the tiredness/weakness, Chills, fever, headache, ➢ First, always check doctors
synthesis by following signs of liver seizures order.
Brand name: Pharmacolog inhibiting the final infections caused problems (such as ➢ Introduce oneself and ask
Ceftin/Zinacef c: step-in cross- by susceptible nausea/vomiting that CV: for the patient’s name and
Second linking organisms: doesn't stop, Edema birthdate.
generation peptidoglycan Respiratory tract ➢ Identify or determine history
stomach/abdominal
cephalosporin strands. infection, Urinary EENT: of drug allergy and to
pain, yellowing
Peptidoglycans tract infections, Hearing loss, oral determine previous use of
makes the cell eyes/skin, dark candidiasis
urine), signs of
membrane rigid Skin to skin kidney problems and reaction to penicillin or
and protective. structure infections. (such as change in Gl: cephalosporins.
Without it, bacterial the amount of urine), Abdominal cramps, ➢ Assess for signs and
cells rupture and Contraindication: signs of new diarrhea, elevated liver symptoms of infection.
die. -Contraindicated infection (such as enzymes, hepatic ➢ Keep in mind the five rights
with allergy to sore throat that failure, hepatomegaly, before giving medication.
Cephalosporins or nausea, ➢ Always assess respiratory
doesn't go away,
Penicillin. Use pseudomembranous status of the patient prior to
fever), easy
Reference: cautiously with colitis, vomiting. giving the medication.
Learning, J. renal failure, bruising/bleeding,
Learning B. lactation and jerky movements, GU: During:
(2019). Nurse’s pregnancy. mental/mood Elevated BUN level, ➢ Encourage the patient to eat
Drug Handbook changes (such as nephrotoxicity, renal meal before taking the
(8th edition pg. 219) -Hypersensitivity to confusion). failure, vaginal medication or tell the patient
cefuroxime, other candidiasis that she may take drug food.
cephalosporins, or ➢ Instruct the patient to ensure
their components. HEME: they take the full course of
Eosinophilia, the medicine.
hemolytic anemia, ➢ Do not crush the given
hypoprothrombinemia, medication.
neutropenia ➢ Instruct to take medicine in
thrombocytopenia, equal dose around the clock
unusual bleeding to maintain level in the
blood.
MS: ➢ Drink plenty of water.
Arthralgia
After:
RESP: ➢ Educated that this drug is
Dyspnea specific for this infection
and should not be used to
SKIN: self-treat other problems.
Ecchymosis, erythema, ➢ If the patient experiences
erythema, multiforme, symptoms of an allergy,
pruritus, rash, Steven-
such as a rash, wheezing,
Johnson syndrome
itching, fever, or swelling in
Other: the joints, this should be
Anaphylaxis; reported.
Injection-site edema, ➢ Educated the client
 pain, and redness; that they may
superinfection experience these side
effects: stomach
upset or diarrhea

NAME OF DOSAGE/FRE CLASSIFIC MECHANISM INDICATIONS/ SIDE EFFECTS ADVERSE NURSING RESPONSIBILITIES
DRUG Q/ ATION OF ACTION CONTRAINDICA EFFECTS
ROUTE TIONS
/SUPPLIED
Generic Name: Dosage/Route/ Therapeutic: A metronidazole Indication: Frequent: Oral therapy may Before:
Metronidazole Frequency: Antibacterial, derivative that Treatment of the Systemic: result!in furry tongue, ➢ First, always check doctors
Anaerobic antiprotozoal. disrupts bacterial following anaerobic Anorexia, nausea, dry glossitis, cystitis, order.
Brand name: Infections and protozoal infections: Intra- mouth, metallic taste. dysuria, pancreatitis. ➢ Introduce oneself and ask
Flagyl PO. IV: Pharmacolog DNA, inhibiting abdominal Peripheral neuropathy for the patient’s name and
ADULTS, c: nucleic acid infections (may be Vaginal: Symptomatic (manifested as birthdate.
ELDERLY: Nitroimidazol synthesis. used with cervicitis/vaginitis, numbness, tingling of ➢ Question for history of
500 mg e derivative. cephalosporin), abdominal cramps, uterine hands/feet) usually hypersensitivity to
96-8h. Therapeutic Effect: Gynecologic pain. is reversible if metronidazole, other
Maximum: 4 Produces infections, Skin and treatment is stopped metronidazole derivatives
g/day. bactericidal, skin structure Occasional: immediately upon (and parabens with topical).
PO: antiprotozoal, infections, Lower Systemic: Diarrhea, appearance of ➢ Obtain specimens for
CHILDREN, amebicidal, and respiratory tract constipation, vomiting, neurologic symptoms. diagnostic tests, cultures
INFANTS: 15- trichomonacidal infections, Bone dizziness, erythematous Seizures occur before giving first dose
35 effects. and joint infections, rash, urticaria, reddish- occasionally. (therapy may begin before
mg/kg/ day in Produces anti- CNS infections. brown urine results are known).
divided doses inflammatory and Septicemia, ➢ Assess for signs and
a8h. immunosuppressive Endocarditis. Topical: Transient symptoms of infection.
Maximum: effects when erythema, mild dryness, ➢ Keep in mind the five rights
2,250 mg/day. applied topically. -Amebiasis burning, irritation, stinging, before giving medication.
IV: -Trichomoniasis tearing when applied too ➢ Always assess respiratory
CHILDREN, -Antibiotic close to eyes. status of the patient prior to
INFANTS: 30 Reference: associated Vaginal: Vaginal, perineal, giving the medication.
mg/kg/day in 3 Saunders Nursing pseudomenbranous vulvar itching; vulvar
divided doses. Drug Handbook colitis swelling. During:
Maximum: 2006. St. Louis -Helicobacter ➢ Encourage the patient to eat
1,500 2006, Elsevier pylori infections Rare: meal before taking the
mg/day. -Bacterial vaginosis Mild, transient leukopenia; medication or tell the patient
-Intravaginal thrombophlebitis with IV that she may take drug food.
-Rosacea therapy. ➢ Instruct the patient to ensure
they take the full course of
Contraindication: the medicine.
-Hypersensitivity to ➢ Do not crush the given
metronidazole or medication.
other metronidazole ➢ Instruct to take medicine in
derivatives (also equal dose around the clock
parabens with to maintain level in the
topical application). blood.
➢ Drink plenty of water.

After:
➢ Educated that this drug is
specific for this infection
and should not be used to
self-treat other problems.
➢ Monitor daily pattern of
bowel activity, stool
consistency.
➢ Monitor I&O, assess for
urinary problems.
➢ Be alert to neurologic
symptoms (dizziness,
paresthesia of extremities).
➢ Assess for rash, urticaria.
➢ Monitor for onset of
superinfection
(ulceration/change of oral
mucosa, furry tongue,
vaginal discharge,
genital/anal pruritus)
➢ Inform patient that Urine
may be red-brown or dark.