equally absorbed from abdomen, thighDose: 15-30mg (up to 45mg) OD after meal

Also lowers triglyceride levels

role in treatment of NASH (Non-alcoholic Steatohepatitis)

In NASH, you get a fatty liver as part of the insulin resistance.

lead to CHF) and cause the ff.: edema, anemia, weight gain, macular edema
Decrease bone mineral density (can lead to fractures)
Exacerbate Grave’s ophthalmopathy
Hepatotoxicity has not been associated with Pioglitazone
(?)Urinary bladder carcinoma
Significant hepatic dysfunction (ALT > 2.5x upper limit of normal)
CHF (those with S/Sx of fluid retention), cardiac disease)
Voglibose (Basen)
in intestinal brush border delaying CHO absorption
This is because the enzyme α-glucosidase is needed in the digestion of carbohydrates
in intestinal lumen.