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This module was designed and written with you in mind. It is here to help you to deepen your knowledge
about Coordinated Functions of the Endocrine, and Reproductive Systems. The scope of this module permits it to be
used in many different learnings situations. The Languange used recognizes the diverse vocabulary level of studnets.
The lessons are arranged to follow the standard sequence off the course. But the order in which you read them can
be changed to correspond with the textbook you are now using
1) Explain the role of hormones involved in the female and male reproductive
system.
a. Describe the parts of the endocrine and reproductive systems.
b. Explain how endocrine and reproductive systems perform
coordinated functions.
c. Cite some ways on how to take good care of the endocrine and
reproductive systems.
What’s In
Directions: Identify if the following parts of the body are related to Endocrine System or Reproductive Sytem. Write
ES for Endocrine System and RS for Reproductive System on the space provided for.
What’s New
Now that you know some of the terms related to Endocrine System and Reproductive System, it is the time
to get to know the particular Endocrine gland involved in the situations given.
Study each situation that depicts the involvement of a particular gland in the Endocrine system. Write down
the name of the endocrine gland. Choose your answer from the word bank below.
WORD BANK
Ovaries Pancreas Pituitary
Adrenal gland Thymus Gland Thyroid gland
What Is It
The Endocrine System
The endocrine gland is composed of glands that secrete different types of hormones that affect almost every
cell, organ, and function of our body. It is essential in regulating growth and development, metabolism, as well as
reproductive processes and mood.
Endocrine glands secrete chemicals known as hormones into the bloodstream, which carries them
throughout the body. When a hormone in the blood reaches the target organ, it produces a notable effect. The
endocrine system sends signals all over the body, much like the nervous system but the effects can take a few hours
or even weeks.
The table below shows the location, hormones released and function of each gland.
The female reproductive system, is also regulated by hormones. These hormones are estrogen and
progesterone. The follicles produce hormones that control the growth and release of eggs from the ovaries. While
other hormones prepare the uterus so a baby can grow in it, other hormones still control the stretching of the uterus
during pregnancy. What’s More
Instructions: Understand the following questions and write your answer on the space provided.
1. What part of the male reproductive system plays an important role in the secretion of the male sex
hormones?
_______________________________________________________________________________________
_____________________________________
2. What part of the female reproductive system secretes the female sex hormones?
_______________________________________________________________________________________
_____________________________________
4. Breastfeeding releases oxytocin & prolactin, hormones that relax the mother and make her baby feel more
nurturing toward her baby. On the other hand, how does the baby benefit from the production of these
hormones in the mother’s body?
_______________________________________________________________________________________
_______________________________________________________________________________________
Match each gland in column A with the corresponding function in column B. Write the letter of your choice
on the space before the number.
A B
Science10 Q3 Module
4 DNA and Gene Mutation
Protein Synthesis
Lesson 1
COMPETENCY CODE
Explain how protein is made using information from DNA S10LT-IIId-37
In this particular lesson, you will gain knowledge on how the proteins are made using the informations in
the DNA.
What’s In
In Grade 9 Science, you learned how genetic information is organized in genes on chromosomes and the
different patterns of inheritance.
In this particular lesson, you will to gain information on how those genetic information embedded in the
DNA work to form proteins but first let’s have a quick overview about the DNA and RNA with their chemical
composition.
What’s New
True or False:
1. Conversion of messages carried by mRNA into amino acid sequences is called ____________.
A. Translation B. DNA repair C. Transcription D. Replication
2. Which of the following is considered a start codon?
A. GUG B. UAG C. AGG D. AUG
3. Which of the following is NOT a stop codon?
A. UGA B. UAG C. GGA D. UAA
4. Which of the following bases pairs with guanine?
A. Guanine B. Cytosine C. Uracil D. Thymine
5. Genomic DNA is ________ resulting in the production of _________.
A. Translated, protein C. Transcribed, mRNA
B. Replicated, mRNA D. Transcribed, DNA
What Is It
DNA contains four bases: adenine (A), guanine (G), cytosine (C), and thymine (T). A and G are double-
ring structures called purines; T and C are single-ring structures called pyrimidines. The nucleotide is the building
block of DNA. It is made up of four bases, a five-carbon sugar deoxyribose, and a phosphate group.
RNA is a single stranded molecule with no helix. The four bases are
DNA RNA
Sugar Deoxyribose Ribose
Bases A,T,G,C A,U,G,C
Strands Double strands Single strand
Helix Yes No
Proteins control the activities of the cell, and so the life of the entire organism. But, how does DNA make a
unique protein that will perform special function?
Hundreds of Amino Acids are linked together to make one Protein. There are 20 Types of Amino Acids and there
are infinite combinations of amino acids. These long chains are called polypeptide chains. Protein Synthesis is the
process in which a cell makes protein based on the message contained within its DNA. However, the DNA is only
found in the nucleus and proteins are only made outside the nucleus (cytoplasm).
The job of RNA (ribonucleic acid) is to carry messages from the DNA (in the nucleus) to the ribosomes (in
the cytoplasm).
mRNA strand: A U G C G U A C U U G A
Note that Thymine in the DNA will be replaced with Uracil in the RNA.
2. Translation – the mRNA, with the help of the ribosome, forms a chain of amino acids (eventually forming a
protein) based on the information contained on mRNA.
Now that our mRNA molecule has been made, it’s time for its message to be made into a protein sequence.
First, divide the mRNA sequence into codons. Codons are three-base sections of mRNA:
AUG|CGU|ACU|UGA
Since each 3-letter combination “codes” for an amino acid, you need to figure out what amino acid matches
up with each codon:
AUG - ?
CGU - ?
ACU - ?
UGA - ?
Based on the table of genetic code the proteins present in the mRNA sequence are:
AUG – Met
CGU – Arg
ACU – Thr
UGA – Stop
What’s More
What mRNA strand will be made from the following DNA sequence? From the mRNA strand that you’ll
get, find the protein sequence that can be made.
DNA Sequence: C A T G T C G A T
True or False:
________4. The job of RNA (ribonucleic acid) is to carry messages from the DNA (in the nucleus) to the ribosomes
(in the cytoplasm).
Science10 Q3
Module4 Protein Synthesis and Gene Mutation
Gene Mutation
Lesson 2
COMPETENCY CODE
Explain how mutations may cause changes in the structure and S10LT-IIIe-38
function of a protein
In this particular lesson, you will learn about gene mutation and how it occurs.
What’s In
In Lesson 1 of this module you learned how protein is synthesized using DNA information.
What’s New
In this lesson, you will learn about gene mutations may cause changes in the structure and function of
protein,how it occurs and its types.
What Is It
Mutation is the ultimate source of all genetic variation, and genetic variation is absolutely necessary for
any sort of evolution to proceed. It is a process that produces a gene or chromosome that differs from the wild type.
A mutant on the other hand, is the organism or cell whose changed phenotype is attributed to a mutation.
There are several types of mutation:
DELETION wherein a base is lost
INSERTION wherein an extra base is inserted
Deletion and insertion may cause what’s called a FRAMESHIFT, meaning the reading “frame” changes, changing
the amino acid sequence.
mRNA Sequence: A U G U G G A A C C G C U G C U G A
Will there likely be effects? YES What kind of mutation is this? SUBSTITUTION – NONSENSE
What’s More
Complete the boxes below. Classify each as either Deletion, Insertion, or Substitution AND as either
frameshift, missense, silent or nonsense (hint: deletion or insertion will always be frameshift).
mRNA Sequence: U U C U A C U U G A G U A C A U G A
What is the change? Copy the original DNA sequence and underline what was changed.
____________________________________________________________________
Will there likely be effects? _____ What kind of mutation is this? ________________
______________________________________________
2. Can a very slight change in the sequence of DNA/mRNA result to mutation? Why?
______________________________________________
______________________________________________
Science 10
Q3 Sources of Evidence for Evolution
Module 5
Evidence from Fossil Records
Lesson 1
COMPETENCY CODE
Explain how fossil records, comparative anatomy, and genetic information S10LT-IIIf-39
provide evidence for evolution
What’s In
Organisms inhabiting the earth have changed overtime, their structures, traits and abilities allowed
them to adapt and survive in their environment. Data from the fossil records, anatomy and morphology, embryonic
development and biochemistry could be analyzed to demonstrate if evolution of life on earth has taken place.
What’s New
Complete the crossword puzzle below by filling in a word that fits each clue.
What Is It
Fossils are examples of evidences that palaeontologists (persons who study fossils) use in studying
evolution. They are traces of organisms that lived in the past and were preserved by natural processes or catastrophic
events. They can be remains of organisms which include bones, shells, teeth and also feces embedded in rocks, peat,
resin and ice.
Most fossils were commonly found in sedimentary rocks. They were from the hard parts of the organism
like woody stem, bones or teeth.
Imprint – are shallow external molds left by animal or plant tissue with little or no organic materials
present.
1. Relative dating- a method used to determine the age of the rocks by comparing them with the rocks in
the other layer. The younger sedimentary rock layer is assumed to be found on top and the older rock is found at the
bottom layer. Fossils found in the bottom layer are assumed to be older than those found in upper layer
2. Radiometric dating- a method used to determine the age of rocks using the decay of radioactive
isotopes present in rocks.
3. Carbon dating- is used to tell the age of organic materials. All organisms have decaying Carbon-14 in
it. Plants and animals that are still alive constantly replace the supply of carbon in their body and the amount of
Carbon-14 in their body stays the same. When an organism dies, Carbon-14 starts to decay. Carbon-14 breaks down
or decays to form Nitrogen-14: the rate of this decay is constant e.g. half of the remaining Carbon-14 breaks down
every 5730 years.
Out of the examination of the layers of rocks and dating fossils, scientists were able to develop the
Geologic Time Scale. The Geologic Time Scale shows the major events in the Earth’s history. It also shows the
appearance of various kinds of organisms in a particular period of time on earth. Era is the largest division of
Geologic Time Scale, namely PreCambrian, Paleozoic, Mesozoic and Cenozoic. Each Era is further divided into
Periods.
Another hint of evolutionary concept is from the comparative anatomy. Structures from different species
which have similar internal framework, position, and embryonic development are considered to be homologous.
Homologous structures may perform different functions in the species living in the different environment,
or it may have the same origin but different functions.
Here are some examples of homologous structures: forelimbs of dog, bird, lizard, and whale, which are
structurally the same, but functionally different.
Structures of unrelated species may evolve to look alike, because the structure is adapted to similar
function. These are called analogous structures.
Analogous structures have similar functions but different origin. Examples are wings of birds, bats, and
insects that have the same function but different in origin.
Example Forelimbs of bat and whale Wings of birds, bat and butterfly
Divergent Evolution
Convergent Evolution
Convergence is an increase in similarities
among species derived from different ancestors as
a result of similar adaptation to similar environment.
In convergent evolution, analogous
structures of unrelated organisms from different
ancestors develop similar function such as butterfly
wings and bird wings.
Another evidence of evolution is provided by the biochemical analysis and amino acid sequence of the
organism’s DNA. These tools may provide identity and are used in the classification of organisms to their
respective genus and species.
An amino acid is one of the building blocks of a protein. A gene’s DNA sequence determines the order of
amino acids that make up a protein, so changes in the DNA sequence often result in changes in the amino acid
sequence as well. By looking for amino acid sequence differences between species, scientists can infer how closely
or distantly related two species are in the evolutionary time.
The greater the similarity in amino acid sequence, the closer the
relationship of the organisms. The organisms which are similar in structure and also possess similarity at the
biochemical level could probably have a common ancestor.
Similarity in their amino acid sequence may suggest similarity in their DNA sequence. It also suggest the
closer relationship of the organisms.
Lesson 1
COMPETENCY CODE
Explain the occurrence of evolution S10LT-IIIg-40
What’s In
In the previous module, you have learned, through the various evidences presented e.g. fossil
records, comparative anatomy and amino acid sequence, that evolution of organisms really happened. In this
module, you would understand why reproduction, variation and adaptation are necessary for the survival of
species. You will be able to explain why evolution is important for living things’ diversity and why diversity is
important for survival.
What’s New
1. In Diagram 1, how many sets of footprints are there? Based on the size of footprints, describe the organisms.
1. What Is It
Lamarck’s Theories of Evolution
Jean Baptiste de Lamarck was the first evolutionist to
believe that organisms change over time. Using fossil records as a guide, Lamarck
was able to develop three theories;
1. The Theory of Need- which states that organisms change in
response to their environment. Their ability to survive helped
them develop characteristics necessary for them to adapt in a
given environment.
2. The Theory of Use and Disuse- which according to Lamarck, organs not in use
will disappear while organs in use will develop. Lamarck believed that giraffes
before have short necks, but because of the need to survive and in order to reach tall
trees for food, they kept stretching their necks until these became longer and able to
reach taller trees.
3. The Theory of Acquired Characteristics- These acquired characteristics, that the parent organism acquired
through use or disuse during its lifetime were believed to be inherited by their offsprings and propagated by the next
generation.
Many scientists rejected the theories of Lamarck. They understood that if there were changes in cell or
body structure, there could be changes in the genetic information of the species.
Darwinian Theory
The more popular Theory of Evolution proposed by Charles Darwin based on
natural selection is different from the theories of Lamarck.
According to Darwin, giraffe species originally had varying neck lengths but
natural selection favored the survival of giraffes with longer necks that could feed on
taller trees that were available. Giraffes with shortneck were eliminated due to lack of
accessible food supply.
Fifty years after Lamarck’s Theory of Use and Disuse,
Charles Darwin suggested the Theory of Natural Selection, after his voyage to the
Galapagos Island in HMS Beagle. He was fascinated by the diversity of organisms he
found along the journey.
In Galapagos Island, he observed that finch species have different beak
structures for different food types. The abundance of certain finch species in an island
was somehow related to the type of available food for these birds.
Darwin suggested that selection also takes place in nature. In selective breeding, farmer identifies and
selects the best and desirable trait to propagate. In natural selection, environmental factors promote the survival of
the fittest and eliminates the less fit.
Organisms struggle for existence in order to survive; they compete for food and space. Organisms
with favourable and advantageous characteristics survive and reproduce. Fitness refers to the ability of an organism
to survive and produce offsprings. Different individuals in a population possess different characteristics and
abilities. This is called variation.
Variation among individuals in the population would likely bring greater chance of survival. An organism
that is adapted and has structures that fitted to survive in a given environment would likely produce offsprings.
What’s More
Think about the mice shown below. Using the space below numbered 1, describe what is happening from
figure 1 to figure 3.
Adapted from the University of California, Los Angeles Life Sciences 1 Demonstration Manual.
Copyright2010
by Drs. Jennifer Doherty and Ingrid Waldron, Department of Biology, University of Pennsylvania
(yumpu.com)
1._____________________________________________________________________________________
_______________________________________________________________________________________
_______________________________________________________________________________________
_______________________________________________________________________________________
_________________________
2. Is the population of mice different in figure 3 than in figure 1? Explain.
3. What characteristic is favoured for survival?
4. Which type of mice are the “fittest’?
5. If you are the white mouse, what will you do in order for you to survive?
1.What do you think are the characteristics necessary for an organism to survive in any changes in the environment?
2. How can changes and disturbances in the environment affect the survival of the species?
4. In what way can you help to protect our natural resources and save our biodiversity?
What I Can Do
Write an essay about the things an individual must do in order to adapt and survive the changes
that are happening in his/her environment.
Additional Activities
The pictures below summarize the Natural Selection theory of evolution. In the space below,
summarize nature’s way of selecting survivors in your own words.
______________________________________________________________________________________
______________________________________________________________________________________
___________________________________________________________________________
Science 10
Q3 Ecosystem: Biodiversity
Module 7
What’s In
In the previous module, you have learned how evolution through natural selection can result in
biodiversity.
In this module, you will learn how biodiversity can influence the stability of an ecosystem, the relationship
between population growth and carrying capacity of a specific environment. You will become aware of the different
human activities that have a negative impact on the environment and proposed projects that will help protect and
conserve the biodiversity you have in your community.
What’s New
Locate in the grid the words identified by the statements below. Fill in the statements with the
correct terms.
____________2. A community of organisms that live, feed and interact with the environment.
____________3. The total number of organisms of the same species in the same area.
____________4. The capability of an ecosystem to be self-regulating and returns it to a steady state after a
disturbance.
Biodiversity is a term that describes how varied living things are in a specific area. Organisms are part of
the biodiversity and very valuable. The value of species or organisms can be divided into various categories:
Products are sources of species that prevent soil species provide visual or
food erosion and floods artistic enjoyment
medicine absorb pollutants forested landscape
clothing cycle materials in the soil calming beauty of a nature
shelter park
energy prayer mountains used for
spiritual meditation
No matter how small an organism is, it has an important role to play in an ecosystem.
Greater biodiversity ensures natural sustainability for all forms of life. Stability of an ecosystem can be
described as the resilience to withstand changes that may occur in the environment. There are many changes that
occur in the environment which may result of natural or human activities. These changes may severely reduce
biodiversity and result to the instability of the ecosystem.
What’s More
Given the value of the given organism, classify each by checking on the space under the correct
column.
___________________________________________________________________
3. What are the ways that human activity can reduce biodiversity?
___________________________________________________________________
___________________________________________________________________
What I Can Do
What can you do to improve the biodiversity of you own home, both inside and outside.
Science 10
Q3 Ecosystem: Biodiversity
Module 7
Limiting Factors
Lesson 2
COMPETENCY CODE
Explain the relationship between population growth and carrying capacity S10LT-IIIi-42
What’s In
In the previous lesson, you have known about the importance of biodiversity in environmental stability. Let
us now try to examine how the population of organisms in an ecosystem affects biodiversity.
What’s New
Populations that are growing or diminishing can be indicators of problems in the environment and
the reasons behind should have been known before finding for a solution.
Before finding out the resons why a population’s size change, let us first understand some
important facts:
Death rate (mortality)-is the number of organisms that are dying in a population.
Thus if the birth rate is greater than the death rate, a population will grow. If the death rate is greater than
the birth rate, then the population will decrease.
When the human population is currently growing at an exponential rate. This means that the birth rate of
human is greater than the death rate.
1. The human population is currently growing at an exponential rate. How can this be explained in terms of
birth and death rates?
2. The monkey-eating eagle ( Pithecophaga jefferyi) is considered an endangered species. What does this
mean in terms of the birth rate and death rate of monkey-eating eagle?
What is It
While populations would probably continue to grow in size, a population of organisms cannot grow
forever, its growth will be limited or stopped, at same point, and the death rate will be greater than the birth rate. A
population’s growth is limited by two general factors: Density-independent factors and Density-dependent
factors.
If a population density is very high, that means there are lots of organisms crowded into a certain area. If a
population’s density is low, that means there are very few organisms in an area.
1. Natural Disasters- such as tropical cyclones, floods, earthuakes and fires will stopa population from
growing no matter how many organisms are living in a certain area.
2. Sunlight and Temperature – the amount of sunlight and if temperature increases due toglobal
warming, will cause the population’s number to decrease, no matter how large or small the population was to
begin with.
3. . Human Activities- activities that can alter the the environment will also decrease the number of
organisms in a population, regardless of the size of the population.
1. Diseases and parasites – Infectious diseases and parasites spread faster in density populated areas.
2. Competition for resources – Organism with better adaptations to obtain(food) resources will be able to
reproduce more often and its population will grow. The organisms that have limited abilities to compete
for the resources will not reproduce as often, may not be fit enough to live long, and can cause their
population to decrease.
3. Predation – plenty of prey are available, predators will be able to eat sufficiently, thus have energy to
reproduce much and increase their numbers.
4. Emigration – occurs when, as population approaches its carrying capacity, and individual organisms
leave and go to a new area where they can find enough resources for survival and reproduction. This will
obviously cause a decrease in the amount of organisms in a population.
What’s More
Read the causes on the left side of the table then predict and write the effect on the the right side of
the table.
CAUSE EFFECT
Read each situation in the table below, then state if it is a density-indepemdent limiting factor or a
density-dependent limiting factor. Indicate the specific limiting factor that is occurring.
Density-independent or
Situation Density-dependent? Limiting Factor
Mrs. Garcia has 55 students in her Biology class, but she has a
room for 50. Because her room was crowded, the 5 students
were asked to go to the curriculum chairperson to change their
schedules.
What I Can Do
You have learned how a certain activity or phenomena affects the environment, now, think of a
pressing environmental concern in our country today and how you can help solve it.