‫‪Machine Translated by Google‬‬

‫ﺑﺎ ت‬
‫ﻣﻀﺎدا ت اﻟﻤﻴﻜﺮو‬
‫ﺘﺮﻓﻮن ﻓ ﻲ اﻟﺨﻄﻮط اﻷﻣﺎﻣﻴ ﺔ‬
‫اﻟﻤﻤﺮﺿﻮن ﻫﻢ ﻣﺤ‬
‫ﺑﺎ ت‬
‫ﻳﺸﺎرﻛﻮن ﻓ ﻲ ﻣﻜﺎﻓﺤ ﺔ ﻣﻘﺎوﻣ ﺔ ﻣﻀﺎدا ت اﻟﻤﻴﻜﺮو‬
Machine Translated by Google

‫ﻣﻮادﺗﻌﻠﻴﻤﻴ ﺔ ﻣﺠﺎﻧﻴ ﺔ‬
‫‪Machine Translated by Google‬‬

‫ﻣﻘﺪﻣ ﺔ‬
‫ﺑﺎ ت‬
‫ﺘﻬﺎ‬
‫ﺑﺎ ت‪ :‬ﻋﻼج اﻻﻟ‬
‫•ﻣﻀﺎدا ت اﻟﻤﻴﻜﺮو‬

‫•ﺧﻔﺾ ﻣﻌﺪل اﻟﻮﻓﻴﺎ ت‪• .‬زﻳﺎدة‬

‫ﺘﻮﻗﻊ‬
‫ﺘﻮﺳﻂ اﻟﻌﻤﺮ اﻟﻤ‬
‫ﻣ‬

‫ﺘﻌﺪدة‪ :‬اﻟﻘﻴﻮد اﻟﻤﻔﺮوﺿ ﺔ ﻋﲆ اﻟﺨﻴﺎرا ت اﻟﻌﻼﺟﻴ ﺔ‬

‫ﺘﻴﺮﻳﺎ اﻟﻤﻘﺎوﻣ ﺔ ﻟﻸدوﻳ ﺔ اﻟﻤ‬
‫ﺒﻜ‬‫•اﻟ‬
Machine Translated by Google
‫‪Machine Translated by Google‬‬

‫ﺑﻞ اﻟﻌﺪوى‬
‫ﺘﻌﻤﺎر ﻣﻘﺎ‬
‫اﻻﺳ‬

‫ﺛﺮ‪،‬‬
‫ﺘﻜﺎ‬
‫ﺘﻮى ﻣﻌﻴﻦ ﻣﻦ اﻟ‬
‫ﺑﻤ ﺴ‬‫ﺘﻢ ﻣﻦ ﺧﻼﻟﻬﺎﺗﻮاﺟﺪ اﻟﻜﺎﺋﻨﺎ ت اﻟﺤﻴ ﺔ اﻟﺪﻗﻴﻘ ﺔ ﻓ ﻲ اﻟﻤﻀﻴﻒ‪،‬‬
‫ﺘ ﻲﻳ‬
‫ﺘﻌﻤﺎر‪ :‬اﻟﻌﻤﻠﻴ ﺔ اﻟ‬
‫•اﻻﺳ‬
‫ﺘﺎج ﻣﺮضﺳﺮﻳﺮي‪.‬‬
‫وﻟﻜﻦ دون إﻧ‬

‫ﺑﻴ ﺔ وﻣﻨﺎﻋﻴ ﺔ‪،‬‬

‫ﺘﻬﺎ‬
‫ﺑ ﺔ اﻟ‬
‫ﺘﺠﺎ‬
‫•اﻟﻌﺪوى‪:‬ﺗﻨﻄﻮي ﻋﲆ ﻏﺰو اﻟﻜﺎﺋﻨﺎ ت اﻟﺤﻴ ﺔ اﻟﺪﻗﻴﻘ ﺔ ﻓ ﻲ أﻧ ﺴﺠ ﺔ اﻟﺠ ﺴﻢ اﻟﻤﻀﻴﻒ‪ ،‬ﻣﻊﺗﻮﻟﻴﺪ اﺳ‬
‫ﻣﻤﺎﻳﺆدي إﱃ ﻣﺮضﺳﺮﻳﺮي وﻳﺆدي إﱃ ﻇﻬﻮر ﻋﻼﻣﺎ ت وأﻋﺮاض‪.‬‬
‫‪Machine Translated by Google‬‬

‫ﻋﻼﻣﺎ ت وأﻋﺮاض اﻟﻌﺪوى‬

‫ﺘﻌﻤﺎرﻳﺆدي إﱃ اﻟﻌﺪوى‬
‫•ﻟﻴ ﺲ ﻛﻞ اﻻﺳ‬

‫ﺘﻌﻤﺎر ﻣﺆﻗ ﺖ أو داﺋﻢ أوﺗﻄﻮر اﻟﻌﺪوى‬

‫ﺘﻌﻤﺎر >=اﺳ‬
‫•اﻻﺳ‬

‫ﺑﻌﺾ اﻷﺣﻴﺎنﻳﻨﻄﻮي ﻋﲆﺗﻐﻴﻴﺮا ت ﻓ ﻲ‬‫ﺘﻌﻤﺎر ﻫﻮ ﻋﻤﻠﻴ ﺔ ﻣﻌﻘﺪة‪• :‬ﻓ ﻲ‬

‫•اﻻﺳ‬
‫ﺑﻌﺾ اﻷﺣﻴﺎنﺗﻘﺪمﺳﺮﻳﻊ ﻟﻠﻌﺪوى‬‫ﺘﻌﻤﺮة‪• .‬ﻓ ﻲ‬
‫اﻷﻧﻮاع اﻟﻤ ﺴ‬
Machine Translated by Google

‫ﻋﻼﻣﺎ ت وأﻋﺮاض اﻟﻌﺪوى‬

‫‪Machine Translated by Google‬‬

‫ﺋﻴ ﺴﻴ ﺔ‬
‫اﻟﻤﻔﺎ ﻫﻴﻢ اﻟﺮ‬

‫ﺜﻞ اﻟﻤﻀﺎدا ت اﻟﺤﻴﻮﻳ ﺔ‪ ،‬وﻣﻀﺎدا ت اﻟﻔﻴﺮوﺳﺎ ت‪ ،‬وﻣﻀﺎدا ت‬

‫ﺑﺎ ت‪:‬ﺗﺸﻤﻞ أي ﻋﻮاﻣﻞ )ﻣ‬
‫•ﻣﻀﺎدا ت اﻟﻤﻴﻜﺮو‬
‫اﻟﻔﻄﺮﻳﺎ ت‪ ،‬وﻣﻀﺎدا ت اﻟﻤﻼرﻳﺎ( ﻗﺎدرة ﻋﲆ اﻟﻌﻤﻞ ﺿﺪ اﻟﻜﺎﺋﻨﺎ ت اﻟﺤﻴ ﺔ اﻟﺪﻗﻴﻘ ﺔ‬

‫ﺑﻮاﺳﻄ ﺔ اﻟﻜﺎﺋﻨﺎ ت اﻟﺤﻴ ﺔ اﻟﺪﻗﻴﻘ ﺔ أو ﺻﻨﺎﻋﻴﺎ ً‬

‫ﺑﻮاﺳﻄ ﺔ اﻟﻜﻴﻤﻴﺎﺋﻴﻴﻦ‪.‬‬ ‫ﺑﻴﻮﻟﻮﺟﻴﺎ ً‬‫ﺘﺎﺟﻪ‬
‫ﺘﻢ إﻧ‬
‫•ﻳ‬

‫ﺘﻞ اﻟﻜﺎﺋﻨﺎ ت اﻟﺤﻴ ﺔ اﻟﺪﻗﻴﻘ ﺔ ‪(- :‬ﺳﻴﺪال(‬

‫•ﻗ‬

‫ﺗﻤﻨﻊ ﻧﻤﻮ اﻟﻜﺎﺋﻨﺎ ت اﻟﺪﻗﻴﻘ ﺔ ‪(-‬ﺳﺎﻛﻨ ﺔ(‬

‫•‬

‫ﺘﻴﺮﻳﺎ‬
‫ﺒﻜ‬‫ﺑﺎ ت اﻟﻨﺸﻄ ﺔ ﺿﺪ اﻟ‬
‫•اﻟﻤﻀﺎد اﻟﺤﻴﻮي‪ :‬ﻫﻮ ﻧﻮع ﻣﻦ اﻟﻤﻮاد اﻟﻤﻀﺎدة ﻟﻠﻤﻴﻜﺮو‬
‫‪Machine Translated by Google‬‬

‫ﺋﻴ ﺴﻴ ﺔ‬
‫اﻟﻤﻔﺎ ﻫﻴﻢ اﻟﺮ‬

‫ﺒ ﺔ اﻟﺠﺮام‬
‫ﺑﻴ ﺔ اﻟﺠﺮام وﺳﺎﻟ‬
‫•دواء واﺳﻊ اﻟﻄﻴﻒ‪ :‬ﻟﻪ ﻧﺸﺎط ﺿﺪ اﻷﻧﻮاع إﻳﺠﺎ‬

‫•دواء ﺿﻴﻖ اﻟﻄﻴﻒ‪ :‬ﻟﻪ ﻧﺸﺎط ﺿﺪ ﻣﺠﻤﻮﻋ ﺔ واﺣﺪة ﻓﻘﻂ ﻣﻦ اﻟﻜﺎﺋﻨﺎ ت اﻟﺤﻴ ﺔ اﻟﺪﻗﻴﻘ ﺔ أو ﻧﻮع واﺣﺪ ﻓﻘﻂ‪.‬‬
Machine Translated by Google

‫ﺑﺎ ت‬
‫ﺗﺼﻨﻴﻒ ﻣﻀﺎدا ت اﻟﻤﻴﻜﺮو‬
Machine Translated by Google
‫‪Machine Translated by Google‬‬

‫ﺒﻄﺎ تﺗﺨﻠﻴﻖ ﺟﺪار اﻟﺨﻠﻴ ﺔ‬

‫ﺜ‬‫ﻣ‬

‫ﺘﻴﺮﻳ ﺔ‬
‫ﺒﻜ‬‫ﺘﻬﺪاف ﺟﺪار اﻟﺨﻠﻴ ﺔ اﻟ‬
‫•اﺳ‬

‫ﺘﻴﺪوﻏﻠﻴﻜﺎن‬
‫ﺒ‬‫ﺒ‬‫ﺑﻨﺎءﺳﻠ ﺴﻠ ﺔ اﻟ‬‫ﺘﺪاﺧﻞ ﻣﻊ‬
‫•ﻳ‬

‫ﺘﻴﺪوﻏﻠﻴﻜﺎن‬
‫ﺒ‬‫ﺒ‬‫ﺘﺮﻛﻴ ﺐﺳﻠ ﺴﻠ ﺔ اﻟ‬
‫ﺗﻴﻨﺎ ت ﻟ‬
‫ﺒﺮو‬
‫ﺘﻔﺎﻋﻞ ﻣﻊ اﻟ‬
‫•ﻳ‬

‫ﺘﻴﺪوﻏﻠﻴﻜﺎن‬
‫ﺒ‬‫ﺒ‬‫ﺒﻘ ﺔ اﻟ‬
‫ﺘﻴﺠ ﺔ ﻟﺨﻠﻞ ﻓ ﻲ ﻃ‬
‫ﺘﻴﺮﻳﺎ ﻧ‬
‫ﺒﻜ‬‫•ﻳﺤﺪ ثﺗﺤﻠﻞ اﻟ‬
‫‪Machine Translated by Google‬‬

‫ﺘﺎﻣﺎز‬
‫ﺘﺎ ﻻﻛ‬
‫ﺑﻴ‬‫ﺑﻞ‬
‫ﺒﻨ ﺴﻠﻴﻨﺎز ﻣﻘﺎ‬
‫اﻟ‬

‫ﺜﻞ‬
‫ﺘﺎم ﻣ‬
‫ﺘﺎ ﻻﻛ‬
‫ﺑﻴ‬‫ﺘﻌﺪدة ﻟﻠﻤﻀﺎدا ت اﻟﺤﻴﻮﻳ ﺔ‬
‫ﺘ ﻲﺗﻄﻮر ﻣﻘﺎوﻣ ﺔ ﻣ‬
‫ﺘﻴﺮﻳﺎ اﻟ‬
‫ﺒﻜ‬‫ﺘﺠﻬﺎ اﻟ‬
‫ﺘ ﻲﺗﻨ‬
‫ﺒﺎرة ﻋﻦ ﻣﺠﻤﻮﻋ ﺔ ﻣﻦ اﻹﻧﺰﻳﻤﺎ ت اﻟ‬
‫ﺘﺎﻣﺎز ﻋ‬
‫ﺘﺎ ﻻﻛ‬
‫ﺑﻴ‬
‫ﺘﺎم‪.‬‬
‫ﺑﺎﻛ‬
‫ﺒﻮرﻳﻦ واﻟ ﺴﻴﻔﺎﻣﻴ ﺴﻴﻦ واﻟﻤﻮﻧﻮ‬
‫ﺒﻨ ﺴﻠﻴﻦ واﻟ ﺴﻴﻔﺎﻟﻮﺳ‬
‫اﻟ‬

‫ﺑﺎ ت ﻟﻸدوﻳ ﺔ‪.‬‬

‫ﺛﻴﺮ اﻟﻤﻀﺎد ﻟﻠﻤﻴﻜﺮو‬
‫ﺘﺄ‬
‫و ﻫ ﻲ ﻣﻀﺎدا ت ﺣﻴﻮﻳ ﺔﺗﺪﻣﺮ اﻟ‬
Machine Translated by Google
Machine Translated by Google
‫‪Machine Translated by Google‬‬

‫ﺘﺎﻣﺎز‬
‫ﺘﺎ ﻻﻛ‬
‫ﺑﻴ‬‫ﺑﻞ‬
‫ﺒﻨ ﺴﻠﻴﻨﺎز ﻣﻘﺎ‬
‫اﻟ‬

‫ﺒﻨ ﺴﻠﻴﻦ‬
‫ُﻈﻬﺮ ﺧﺼﻮﺻﻴ ﺔ اﻟ‬
‫ﺘﺎﻣﺎز اﻟﺬيﻳ‬
‫ﺘﺎ ﻻﻛ‬
‫ﺑﻴ‬‫ﺒﻨ ﺴﻠﻴﻨﺎز ﻫﻮ ﻧﻮع ﻣﻦ‬
‫•اﻟ‬

‫ﺒﻨ ﺴﻠﻴﻨﺎز ﻫ ﻲ ﻣﻀﺎدا ت ﺣﻴﻮﻳ ﺔ‪ ،‬و ﻫ ﻲ ﻟﻴ ﺴ ﺖ ﻛﺬﻟﻚ‬ ‫ﺒﻨ ﺴﻠﻴﻨﺎ ت اﻟﻤﻘﺎوﻣ ﺔ ﻟﻠ‬‫•اﻟ‬
‫ﺘﺎ‬
‫ﺑﻴ‬‫ﺒﻨ ﺴﻠﻴﻨﺎز اﻟﺬيﻳﺪﻣﺮ ﺣﻠﻘ ﺔ‬ ‫ﺘﻴﺮﻳﺎ إﻧﺰﻳﻢ اﻟ‬
‫ﺒﻜ‬‫ﺑﻌﺾ اﻟ‬ ‫ﺘﺞ‬‫ﺒﻨ ﺴﻠﻴﻨﺎز‪.‬ﺗﻨ‬ ‫ﺑﻮاﺳﻄ ﺔ إﻧﺰﻳﻢ اﻟ‬‫ﺘﻢﺗﻌﻄﻴﻠﻪ‬‫ﻳ‬
‫ﺒﻨ ﺴﻠﻴﻨﺎ ت اﻟﻤﻘﺎوﻣ ﺔ‬
‫ﺘﺨﺪم اﻟ‬ ‫ﺒﻨ ﺴﻠﻴﻦ ﻏﻴﺮ ﻓﻌﺎل‪.‬ﺗ ﺴ‬ ‫ﺘﺎم ﻟﻠﻤﻀﺎد اﻟﺤﻴﻮي‪ ،‬ﻣﻤﺎﻳﺠﻌﻞ اﻟ‬ ‫ﻻﻛ‬
‫ﺑﺎ ت‪.‬‬‫ﺘﻬﺎ‬‫ﺒﻨ ﺴﻠﻴﻨﺎز ﻟﻌﻼج اﻟ ﺴﻼﻻ ت اﻟﻤﻘﺎوﻣ ﺔ ﻟﻠﻤﻜﻮرا ت اﻟﻌﻨﻘﻮدﻳ ﺔ وﻏﻴﺮ ﻫﺎ ﻣﻦ اﻻﻟ‬‫ﻟﻠ‬
Machine Translated by Google
Machine Translated by Google

‫ﺒﻄﺎ تﺗﺨﻠﻴﻖ ﺟﺪار اﻟﺨﻠﻴ ﺔ‬

‫ﺜ‬‫ﻣ‬
Machine Translated by Google
Machine Translated by Google
‫‪Machine Translated by Google‬‬

‫ﺑﻼزﻣ ﻲ‬
‫ﺘﻮ‬‫ﺒﻄﺎ ت وﻇﻴﻔ ﺔ اﻟﻐﺸﺎء اﻟ ﺴﻴ‬
‫ﺜ‬‫ﻣ‬

‫ﺑﻼزﻣ ﻲ‬
‫ﺘﻮ‬‫ﺘﻴﺮوﻻ ت اﻟﻐﺸﺎء اﻟ ﺴﻴ‬
‫ﺑﺸﻜﻞ ﻻ رﺟﻌ ﺔ ﻓﻴﻪ ﻣﻊﺳ‬‫ﺒﻂ‬
‫ﺗ‬‫ﺗﻘﺎر ب اﻟﺪ ﻫﻮنﻳﺮ‬
‫•‬

‫ﺘﺪﺧﻞ ﻓ ﻲﺗﺨﻠﻴﻖ اﻟﺪ ﻫﻮن‬

‫•اﻟ‬

‫ﺒﺎ ت اﻷﺳﺎﺳﻴ ﺔ اﻷﺧﺮى‬

‫•ﻳﺆدي إﱃﺗﻐﻴﺮا ت ﻓ ﻲ اﻟﻨﻔﺎذﻳ ﺔ‪ ،‬ﻣﻤﺎﻳﺆدي إﱃ ﻓﻘﺪان اﻟﻌﻨﺎﺻﺮ اﻟﻐﺬاﺋﻴ ﺔ واﻟﻤﺮﻛ‬
‫‪Machine Translated by Google‬‬

‫ﺑﻼزﻣ ﻲ‬
‫ﺘﻮ‬‫ﺒﻄﺎ ت وﻇﻴﻔ ﺔ اﻟﻐﺸﺎء اﻟ ﺴﻴ‬
‫ﺜ‬‫ﻣ‬
‫‪Machine Translated by Google‬‬

‫ﺗﻴﻦ‬
‫ﺒﺮو‬
‫ﺒﻄﺎ تﺗﺨﻠﻴﻖ اﻟ‬
‫ﺜ‬‫ﻣ‬
‫ﺒﻮﺳﻮﻣﺎ ت‬
‫ﺑﻂ اﻟﺮﻳ‬
‫•ر‬

‫ﺒﻴﻌﻴ ﺔ أو ﺧﻠﻞ ﻓ ﻲ‬
‫ﺗﻴﻨﺎ ت ﻏﻴﺮ ﻃ‬
‫ﺑﺮو‬‫ﺒﻮزي اﻟﺮﺳﻮل‪ ،‬ﻣﻤﺎﻳﺆدي إﱃ‬
‫ﺒ ﺐ ﻓ ﻲ ﻗﺮاءة ﺧﺎﻃﺌ ﺔ ﻟﻠﺤﻤﺾ اﻟﻨﻮوي اﻟﺮﻳ‬
‫ﺘﺴ‬‫•اﻟ‬
‫ﺗﻴﻨﺎ ت‬
‫ﺒﺮو‬
‫ﺗﺨﻠﻴﻖ اﻟ‬

‫ﺘﻴﺮﻳ ﺔ‬
‫ﺒﻜ‬‫ﺘ ﻲﺗﻤﻜﻦ اﻟﻤﺰﻳﺪ ﻣﻦ اﻟﻤﻀﺎدا ت اﻟﺤﻴﻮﻳ ﺔ ﻣﻦ دﺧﻮل اﻟﺨﻠﻴ ﺔ اﻟ‬
‫ﺒﻴﻌﻴ ﺔ اﻟﻤ ﺴﺎم اﻟ‬
‫ﺗﻴﻨﺎ ت ﻏﻴﺮ اﻟﻄ‬
‫ﺒﺮو‬
‫ﺘﺞ اﻟ‬
‫•ﺳﻮفﺗﻨ‬
Machine Translated by Google

‫ﺗﻴﻦ‬
‫ﺒﺮو‬
‫ﺒﻄﺎ تﺗﺨﻠﻴﻖ اﻟ‬
‫ﺜ‬‫ﻣ‬
‫‪Machine Translated by Google‬‬

‫ﺒﻄﺎ تﺗﺨﻠﻴﻖ اﻟﺤﻤﺾ اﻟﻨﻮوي‬

‫ﺜ‬‫ﻣ‬

‫ﺛﻨﺎء ﻋﻤﻠﻴ ﺔ اﻟﻨ ﺴﺦ‬

‫ﺗﻞ أ‬
‫ﺒ ﺐﺗﻜ ﺴﺮ اﻟﺤﻤﺾ اﻟﻨﻮوي اﻟﻘﺎ‬
‫•ﺧﻠﻞ ﻓ ﻲﺗﺮﻛﻴ ﺐ اﻟﺤﻤﺾ اﻟﻨﻮوي ﻣﻤﺎﻳ ﺴ‬

‫•ﻋﺪة آﻟﻴﺎ ت‪:‬‬

‫ﺒﻴﻂ‬
‫ﺜ‬‫ﺗ‬‫ﺒ ﻲ • )‪(RNA‬‬
‫ﺑﻮﻟﻴﻤﻴﺮاز اﻟﺤﻤﺾ اﻟﻨﻮوي اﻟﺮﻳ‬‫ﺑﻮﺣﺪة ﻓﺮﻋﻴ ﺔ ﻣﻦ‬‫ﺒﺎط‬
‫ﺗ‬‫•اﻻر‬

‫ﺒﻴﻂ ﻋﻤﻠﻴ ﺔ اﻟﻨ ﺴﺦ اﻷوﻟﻴ ﺔ اﻟﻔﻴﺮوﺳﻴ ﺔ‬

‫ﺜ‬‫ﺗ‬‫ﺑﻮﻳﺰوﻣﻴﺮازا ت •ﻓ ﺴﻔﺮة اﻟﻤﻜﻮﻧﺎ ت •‬
‫ﺘﻮ‬‫اﻟ‬

‫ﺛﺮ اﻟﻔﻴﺮوس •ﻣﻨﻊ ﻣ ﺴﺎرﺗﺨﻠﻴﻖ ﺣﻤﺾ اﻟﻔﻮﻟﻴﻚ‬

‫ﺒﻴﻂ ﻋﻤﻠﻴ ﺔﺗﻜﺎ‬
‫ﺜ‬‫ﺗ‬‫•‬
Machine Translated by Google

‫ﺒﻄﺎ تﺗﺨﻠﻴﻖ اﻟﺤﻤﺾ اﻟﻨﻮوي‬

‫ﺜ‬‫ﻣ‬
Machine Translated by Google
‫‪Machine Translated by Google‬‬

‫ﻣﻀﺎدا ت اﻷﻳﺾ‬
‫ﺒﻴﻌﻴ ﺔ‬
‫ﺗﺞ اﻷﻳﻀﻴ ﺔ اﻟﺨﻠﻮﻳ ﺔ اﻟﻄ‬
‫ﺑﻬ ﺔ ﻣﻦ اﻟﻨﺎﺣﻴ ﺔ اﻟﻬﻴﻜﻠﻴ ﺔ ﻟﻠﻨﻮا‬
‫ﺒﺎ ت ﻣﺸﺎ‬
‫•ﻣﺮﻛ‬

‫ﺑﺎﻹﻧﺰﻳﻤﺎ ت‬‫ﺒﺎط‬
‫ﺗ‬‫ﺒﺎ ت اﻟﺨﻠﻮﻳ ﺔ ﻟﻼر‬
‫ﺘﻘﻠ‬
‫ﺘﻨﺎﻓ ﺲ ﻣﻊ اﻟﻤ ﺴ‬
‫•اﻟ‬

‫ﺘﻴﺮﻳﺪﻳﻦ‪،‬‬
‫ﺒ‬‫ﺑﻨﺰوﻳﻚ‪ ،‬اﻟ‬
‫ﺒﻪ أﻣﻴﻨﻮ‬
‫ﺛﻠ ﻲ ﻟﺤﻤﺾ ﺷ‬
‫ﺘﻤﺎ‬
‫ﺑﻪ اﻟﻬﻴﻜﻠ ﻲ اﻟ‬
‫ﺘﺸﺎ‬
‫•اﻟ‬
‫ﺗﻴﻨﺎﻣﻴﺪ‬
‫ﻧﻴﻜﻮ‬

‫ﺘﺎﻣﺎز‬
‫ﺘﺎ ﻻﻛ‬
‫ﺑﻴ‬‫ﺒﻴﻂ ﺣﻠﻘ ﺔ‬
‫ﺜ‬‫ﺗ‬‫ﺑﻂ و‬
‫•ر‬
Machine Translated by Google

‫ﻣﻀﺎدا ت اﻷﻳﺾ‬
Machine Translated by Google
Machine Translated by Google
Machine Translated by Google

‫اﻷدوﻳ ﺔ اﻟﻤﻀﺎدة ﻟﻠﻔﻄﺮﻳﺎ ت‬

Machine Translated by Google
Machine Translated by Google

‫اﻷدوﻳ ﺔ اﻟﻤﻀﺎدة ﻟﻠﻔﻴﺮوﺳﺎ ت‬

Machine Translated by Google
Machine Translated by Google
‫‪Machine Translated by Google‬‬
‫ﻳﻤﻨﻊﺗﺮﻛﻴ ﺐ ﺟﺪار اﻟﺨﻠﻴ ﺔ‬

‫ﺒﻴﻂ‬
‫ﺜ‬‫ﺘ‬‫ﺒﺎدل ﻋﻦ ﻃﺮﻳﻖ اﻟ‬
‫ﺘ‬‫ﺒﺎط اﻟﻤ‬
‫ﺗ‬‫ﺛﻴﻢ‪:‬ﻳﻤﻨﻊ اﻻر‬
‫ﺒﻴﺪ ﻟﻠﺠﺮا‬
‫ﺒﻨ ﺴﻠﻴﻦ )ﻣ‬
‫اﻟ‬
‫ﺘﻴﺪاز(‬
‫ﺒ‬‫ﺒ‬‫ﺘﻨﺎﻓ ﺴ ﻲ ﻹﻧﺰﻳﻢ اﻟ‬
‫اﻟ‬

‫ﺒﻘ ﺔ ‪ /‬اﻵﻟﻴ ﺔ‬
‫اﻟﻄ‬ ‫اﻟﻤﺨﺪرا ت‬ ‫اﻟﻤﺆﺷﺮا ت **(اﻟﺪواء اﻟﻤﻔﻀﻞ(‬ ‫ﺗ ﺴﻤﻢ‬

‫ﺒﻨ ﺴﻠﻴﻦ‬
‫اﻟ‬ ‫ﺒﻨ ﺴﻠﻴﻦ ج‬
‫اﻟ‬ ‫ﺘﻴﺮﻳﺎ‪ .‬اﻟﻤﻘﻴﺤ ﺔ **)‪(Grp.A‬‬
‫ﺑﻜ‬ ‫رد ﻓﻌﻞ ﻓﺮط اﻟﺤ ﺴﺎﺳﻴ ﺔ‬
‫ﺒﻨ ﺴﻠﻴﻦ اﻟﻤﺎﺋ ﻲ ‪G‬‬
‫اﻟ‬ ‫اﻟﺨﻄﻮة‪agalactiae (Grp.B)** C. .‬‬ ‫ﻓﻘﺮ اﻟﺪم اﻻﻧﺤﻼﻟ ﻲ‬
‫ﺒﻨ ﺴﻠﻴﻦ ‪G‬‬
‫ﺑﺮوﻛﺎﻳﻴﻦ اﻟ‬ ‫ﺑﻴﺮﻓﺮﻳﻨﺠﻨﺰ)ﻋﺼﻴﺎ ت(**‬
‫ﺒﻨ ﺴﻠﻴﻦ ج‬‫ﺛﻴﻦ اﻟ‬
‫ﺒﻨﺰا‬
‫اﻟ‬
‫ﺒﻨ ﺴﻠﻴﻦ ‪V‬‬‫اﻟ‬

‫ﺑﻨﻴ ﺴﻴﻠﻴﻦ‬
‫أﻣﻴﻨﻮ‬ ‫ﺒﻴ ﺴﻠﻴﻦ‬
‫اﻷﻣ‬ ‫ﺒﻴ ﺔ‬
‫‪+‬ﺳﻠ‬ ‫ﻓﻮق‬ ‫ﻓﻮق‬
‫أﻣﻮﻛ ﺴﻴ ﺴﻴﻠﻴﻦ‬ ‫اﻟﻐﺮام‪E. Coli** :‬‬
‫**‪E. faecalis‬‬

‫ﺒﻨ ﺴﻠﻴﻨﺎز‬
‫ﺒﻨ ﺴﻠﻴﻨﺎ ت اﻟﻤﻘﺎوﻣ ﺔ ﻟﻠ‬
‫اﻟ‬ ‫ﺜﻴ ﺴﻴﻠﻴﻦ‬
‫ﻣﻴ‬ ‫ﺒﺔ‬
‫ﺘﺠ ﺔ ﻟـ ‪PCNase.‬اﻟﻤﺬ ﻫ‬
‫ﻓﻮق ‪+ Staph+‬اﻟﻤﻨ‬
‫ﻧﺎﻓ ﺴﻴﻠﻴﻦ‬ ‫ﺘﻬﺎ ب اﻟﻜﻠﻴ ﺔ اﻟﺨﻼﻟ ﻲ‬
‫اﻟ‬
‫أوﻛ ﺴﺎﺳﻴﻠﻴﻦ‬
‫ﻛﻠﻮﻛ ﺴﺎﺳﻴﻠﻴﻦ‬
‫دﻳﻜﻠﻮﻛ ﺴﺎﺳﻴﻠﻠﻴﻦ‬
‫ﺒﻨ ﺴﻠﻴﻨﺎ ت اﻟﻤﻀﺎدة ﻟﻠﺰاﺋﻔ ﺔ‬
‫اﻟ‬ ‫ﺑﻨﻴ ﺴﻴﻠﻴﻦ‬
‫ﻛﺎر‬ ‫ﻓﻮق ‪ +‬ﻓﻮق‬
‫ﺗﻴﻜﺎرﺳﻴﻠﻴﻦ‬ ‫اﻟﺰاﺋﻔ ﺔ اﻟﺰﻧﺠﺎرﻳ ﺔ **‬
‫ﺒﻴﺮاﺳﻴﻠﻴﻦ‬
‫ﺑﻴ‬
 ‫ﺘﻴﺪاز(‬
‫ﺒ‬‫ﺒ‬‫ﺘﻨﺎﻓ ﺴ ﻲ ﻹﻧﺰﻳﻢ اﻟ‬
‫ﺒﻴﻂ اﻟ‬
‫ﺜ‬‫ﺘ‬‫ﺘﻴﺮﻳ ﺔ ﻋﻦ ﻃﺮﻳﻖ اﻟ‬
‫ﺒﻜ‬‫ﺛﻴﻢ‪:‬ﻳﻤﻨﻊﺗﺨﻠﻴﻖ ﺟﺪار اﻟﺨﻠﻴ ﺔ اﻟ‬
‫ﺒﻴﺪ ﻟﻠﺠﺮا‬
‫ﺒﻮرﻳﻨﺎ ت )ﻣ‬
‫اﻟ ﺴﻴﻔﺎﻟﻮﺳ‬
‫‪Machine Translated by Google‬‬

‫اﻟﺠﻴﻞ اﻷول‬ ‫اﻟﻤﻜﻮرا ت اﻟﻌﻨﻘﻮدﻳ ﺔ‪.‬‬ ‫ﺳﻴﻔﺎزوﻟﻴﻦﺴ ﺴ ﻲ‬

‫رد ﻓﻌﻞﺗﺤ‬
‫ﺒ ﺔ **اﻟﻤﻜﻮرا ت اﻟﻌﻨﻘﻮدﻳ ﺔ‪.‬‬
‫اﻟﻤﺬ ﻫ‬ ‫ﺒ ﺲ )‪(3٪‬‬
‫ﺑ ﻲ ﻛﻮﻣ‬‫ﺴﻴﻦ‬
‫ﻳﺠﺎ‬ ‫ﺳﻴﻔﺎﻟﻜ‬
‫اﻟﺪم إ‬ ‫ﻓﻘﺮ‬
‫ﺒﻴﺎ ت اﻟﺠﺮام‪:‬‬
‫ﺑﻌﺾﺳﻠ‬ ‫ﺒﺸﺮة **‬ ‫اﻟ‬
‫‪E. Coli Klebsiella‬‬

‫ﺜﺎﻧ ﻲ‬
‫اﻟﺠﻴﻞ اﻟ‬ ‫ﺘﻴﻦ‬
‫ﺒﻴ ﺔ‬
‫ﺳﻠ‬‫ﺴﻴ‬
‫ﺳﻴﻔﻮﻛ ‪+‬‬
‫ﻓﻮق‬ ‫رد ﻓﻌﻞﺗﺤ ﺴ ﺴ ﻲ‬
‫ﺳﻴﻔﺎﻛﻠﻮر‬
‫اﻟﻐﺮام‬ ‫ﺗﻔﺎﻋﻞ ‪ETOH‬دﻳ ﺴﻔﻠﻔﺮام‬
‫ﺳﻴﻔﻮروﻛ ﺴﻴﻢ‬

‫ﺜﺎﻟ ﺚ‬
‫اﻟﺠﻴﻞ اﻟ‬ ‫ﺴﻮن‬
‫ﺒﻴ ﺔ‬
‫ﺳﻠ‬‫ﻳﺎﻛ‬
‫ﺘﺮ ‪+‬‬
‫ﺳﻴﻔ‬
‫ﻓﻮق‬ ‫رد ﻓﻌﻞﺗﺤ ﺴ ﺴ ﻲ‬
‫ﺗﺎﻛ ﺴﻴﻢ‬
‫ﺳﻴﻔﻮ‬
‫اﻟﻐﺮام‬ ‫ﺗﻔﺎﻋﻞ ‪ETOH‬دﻳ ﺴﻔﻠﻔﺮام‬
‫ﺘﺎزﻳﺪﻳﻢ‬‫ﺳﻴﻔ‬
‫ﺋﻔ ﺔ‬
‫اﻟﺰا‬

‫ﺑﻊ(‬
‫ﺒﻴﻢ )اﻟﺠﻴﻞ اﻟﺮا‬
‫ﺳﻴﻔﻴ‬
‫‪Machine Translated by Google‬‬ ‫ﺒﻄﺎ ت ﺟﺪار اﻟﺨﻠﻴ ﺔ اﻷﺧﺮى‬
‫ﺜ‬‫ﻣ‬

‫ﻓﺎﻧﻜﻮﻣﺎﻳ ﺴﻴﻦ‬
‫ﺘﻴﻮﻏﻠﻴﻜﺎن (‬
‫ﺒ‬‫ﺒ‬‫ﺒﺎدل ﻟﻠ‬
‫ﺘ‬‫ﺒﺎط اﻟﻤ‬
‫ﺗ‬‫ﺛﻴﻢ‪:‬ﻳﻌﻄﻞ اﻻر‬
‫ﺒﻴﺪ ﻟﻠﺠﺮا‬‫**‪MRSA‬‬
‫)ﻣ‬ ‫ﻓﺎﻧﻜﻮﻣﺎﻳ ﺴﻴﻦ‬ ‫ﺘﻼزﻣ ﺔ اﻟﺮﺟﻞ اﻷﺣﻤﺮ‬
‫ﻣ‬
‫زﻋﻤﺎء **‪PCN/Ceph‬‬ ‫اﻟ ﺴﻤﻴ ﺔ اﻟﻜﻠﻮﻳ ﺔ‬
‫ﺗﻘﺎﻟﻴ ﺔ‬
‫ﺒﺮ‬‫ﺘﺮﻳﺎ اﻟﻤﻜﻮرة اﻟﻌﻨﻘﻮدﻳ ﺔ اﻟ‬
‫ﺑﻜ‬
‫اﻟ ﺴﻤﻴ ﺔ اﻷذﻧﻴ ﺔ‬
‫ﺒﺸﺮة‬
‫‪S.‬اﻟ‬

‫ﺣﻤﺾ ‪clavulanic‬‬ ‫ﺘﺎﻣﺎز‬

‫ﺘﺎ ﻻﻛ‬
‫ﺑﻴ‬
‫ﺗﻘﺎﻟﻴ ﺔ**‬‫ﺒﻄﺎ ت‬
‫ﺒﺮ‬ ‫ﺜ‬‫ﻣ‬
‫ﺘﺮﻳﺎ اﻟﻤﻜﻮرة اﻟﻌﻨﻘﻮدﻳ ﺔ اﻟ‬
‫ﺑﻜ‬
‫رد ﻓﻌﻞ ﻓﺮط اﻟﺤ ﺴﺎﺳﻴ ﺔ‬
‫ﺘﺎم‬
‫ﺒﺎﻛ‬
‫ﺳﻮﻟ‬ ‫ﺘﻘﺎﻃﻊ(‬
‫ﺒﺎط اﻟﻤ‬
‫ﺗ‬ ‫**‪S‬‬
‫ﻣﻨﻊ اﻻر‬ ‫ﺒﺸﺮة‬
‫ﺒﻴﺪ اﻟﻟﻠﺠﺮا‬
‫ﺛﻴﻢ‪:‬‬ ‫)ﻣ‬ ‫ﻓﻘﺮ اﻟﺪم اﻻﻧﺤﻼﻟ ﻲ‬
‫ﺘﺎم‬
‫ﺑﺎﻛ‬
‫ﺗﺎزو‬ ‫ﺘﺮﻳﺎ ﻗﻮﻟﻮﻧﻴ ﺔ**‬
‫ﺑﻜ‬

‫ﺒ ﺴﻴﻼ**‬
‫ﻛﻠﻴ‬

‫ﺑﻴﻨﻴﻤﺎ ت‬
‫ﺑﺎ‬
‫اﻟﻜﺎر‬ ‫ﺣﻴﻮي‬
‫ﺗﻴﻦ(‬
‫ﺘﺎ‬‫ﺳ‬‫ﻣﻀﺎد‬
‫ﻷي‪(+‬ﺳﻴﻼ‬‫ﻧﺸﺎط‬
‫ﺒﻴﻨﻴﻢ‬ ‫ﺳﻊ‬
‫أو إ‬
‫ﻳﻤﻴ‬
‫ﺑﻼزﻣﺎ(‬ ‫ﺑﻴﻨﻴﻢ‬
‫‪MRSA،‬اﻟﻤﻴﻜﻮ‬ ‫ﺘﻣﻴﺮو‬
‫ﺜﻨﺎء‬‫ﺑﺎﺳ‬
‫)‬
‫ﺒﻴﻨﻴﻢ‬
‫دورﻳ‬
‫ﺑﻴﻨﻴﻢ‬
‫ﺗﺎ‬
‫إر‬

‫ﺗﺮﻳﻮﻧﺎم‬
‫أز‬ ‫ﺗﺮﻳﻮﻧﺎم‬
‫أز‬ ‫ﺒﻴ ﺔ اﻟﺠﺮام‬
‫ﻋﺼﻴﺎ تﺳﻠ‬
‫ﺘﻤﺎرﻳﻦ اﻟﺮﻳﺎﺿﻴ ﺔ‬
‫اﻟ‬

‫ﺘﺸﻔﻴﺎ ت‬
‫ﺒ ﺔ ﻣﻦ اﻟﻤ ﺴ‬
‫ﺘﺴ‬‫اﻟﻌﺪوى اﻟﻤﻜ‬

‫ﺒﻮﻟﻴﻤﻴﻜ ﺴﻴﻨﺎ ت‬
‫اﻟ‬ ‫ﺑﻮﻟﻴﻤﻴﻜ ﺴﻴﻦ ب‬ ‫ﺒﻴ ﺔ اﻟﻐﺮام‬
‫ﺑﺎ ت اﻟﻤﻮﺿﻌﻴ ﺔﺳﻠ‬
‫ﺘﻬﺎ‬
‫اﻻﻟ‬
‫ﺑﻮﻟﻴﻤﻴﻜ ﺴﻴﻦ إي‬

‫ﺘﺮاﺳﻴﻦ‬
‫ﺑﺎﺳﻴ‬ ‫ﺘﺮاﺳﻴﻦ‬
‫ﺑﺎﺳﻴ‬ ‫ﺑﻴ ﺔ اﻟﺠﺮام‬
‫ﺑﺎ ت اﻟﻤﻮﺿﻌﻴ ﺔ إﻳﺠﺎ‬
‫ﺘﻬﺎ‬
‫اﻻﻟ‬
‫‪Machine Translated by Google‬‬

‫ﺗﻴﻦ‬
‫ﺒﺮو‬
‫ﺒﻴﻂﺗﺨﻠﻴﻖ اﻟ‬
‫ﺜ‬‫ﺗ‬

‫ﺒﻮﺳﻮم ‪30S‬‬
‫اﻟﻮﺣﺪة اﻟﻔﺮﻋﻴ ﺔ اﻟﻤﻀﺎدة ﻟﻠﺮﻳ‬

‫ﺛﻴﻢ‪:‬‬
‫ﺒﻴﺪ ﻟﻠﺠﺮا‬
‫أﻣﻴﻨﻮﻏﻠﻴﻜﻮزﻳﺪا ت )ﻣ‬ ‫ﺒﻴ ﺔ اﻟﻐﺮام‬‫ﺴﻴﻦ‬
‫ﺳﻠ‬ ‫ﺘﺎﻣﻴ‬‫اﻟﺠﻨ‬
‫اﻟﻬﻮاﺋﻴ ﺔ‬ ‫اﻟ ﺴﻤﻴ ﺔ اﻟﻜﻠﻮﻳ ﺔ‬
‫ﺑـ )‪30S‬‬‫ﺑﺸﻜﻞ ﻻ رﺟﻌ ﺔ ﻓﻴﻪ‬‫ﺒﻂ‬
‫ﺗ‬‫ﻳﺮ‬ ‫ﻳﺎ اﻟﻤﻌﻮﻳ ﺔ‬‫ﺘﻴﺮ‬
‫ﺴﻴﻦ‬ ‫ﺒﻜ‬‫اﻟ‬
‫ﻧﻴﻮﻣﺎﻳ‬ ‫اﻟ ﺴﻤﻴ ﺔ اﻷذﻧﻴ ﺔ‬
‫ﺋﻔ ﺔ‬
‫أﻣﻴﻜﺎاﻟﺰا‬
‫ﺳﻴﻦ‬

‫ﺑﺮاﻣﻴ ﺴﻴﻦ‬
‫ﺗﻮ‬
‫ﺘﻮﻣﻴ ﺴﻴﻦ‬
‫ﺑ‬‫ﺘﺮ‬
‫اﻟ ﺴ‬

‫ﺘﻞ‬
‫ﺛﻴﻢ‪ :‬ﻛ‬
‫ﺒﻂ ﻟﻠﺠﺮا‬
‫ﺜ‬‫ﺘﺮاﺳﻴﻜﻠﻴﻦ )ﻣ‬
‫ﺘ‬‫اﻟ‬ ‫ﺘ ﺴﻴﺎ‬
‫ﺳﻴﻜﻠﻴﻦ‬‫ﻳﻜﻴ‬‫اﻟﺮ‬
‫ﺘﺮا‬
‫ﺘ‬‫اﻟ‬ ‫ﺒﺪﻳ ﺔ‬
‫اﻟ ﺴﻤﻴ ﺔ اﻟﻜ‬
‫ﺒ ﻲ اﻟﻨﻮوي اﻟﻨﻘﺎل(‬
‫اﻟﺤﻤﺾ اﻟﺮﻳ‬ ‫ﺑﻼزﻣﺎ‬
‫ﺴﻴﻜﻠﻴﻦ‬ ‫اﻟﻤﻴﻜﻮﺴﻴ‬
‫اﻟﺪوﻛ‬ ‫ﺗﻐﻴﺮ ﻟﻮن اﻷﺳﻨﺎن‪ .‬ﺿﻌﻒ اﻟﻨﻤﻮ‬
‫ﺳﻜﻠﻴﻦ‬
‫)ﻣﺮض ﻻﻳﻢ(‬ ‫اﻟﻤﻴﻨﻮ‬
‫ﺒﻴﺎ ت‬‫اﻟﻠﻮﻟ‬
‫دﻳﻤﻴﻜﻠﻮﺳﻜﻠﻴﻦ‬ ‫ﻋﺎﻣﺎ‬
‫ﺒﻪ ﻋﻨﺪ اﻷﻃﻔﺎل أﻗﻞ ﻣﻦ ‪ً 12‬‬
‫ﺗﺠﻨ‬
‫‪Machine Translated by Google‬‬ ‫ﺒﻮﺳﻮم ‪50S‬‬
‫اﻟﻮﺣﺪة اﻟﻔﺮﻋﻴ ﺔ اﻟﻤﻀﺎدة ﻟﻠﺮﻳ‬

‫ﺒﻂ‬
‫ﺗ‬‫ﺛﻴﻢ‪:‬ﻳﺮ‬
‫ﺒﻂ ﻟﻠﺠﺮا‬
‫ﺜ‬‫اﻟﻤﺎﻛﺮوﻟﻴﺪا ت )ﻣ‬ ‫ﺜﺮوﻣﻴ ﺴﻴﻦ‬
‫اﻻرﻳ‬ ‫ﺋﻮي‬
‫ﺘﻬﺎ ب اﻟﺮ‬
‫اﻟﻌﻘﺪﻳ ﺔ ‪H.‬اﻟﻨﺰﻟﻴ ﺔ اﻻﻟ‬ ‫ﺘﻮﻛﺮوم‬
‫ﺗﻔﺎﻋﻞ اﻟﻜﻮﻣﺎدﻳﻦ )اﻟ ﺴﻴ‬
‫ﺑـ )‪50S‬‬‫ﺑﺸﻜﻞ ﻋﻜ ﺴ ﻲ‬ ‫ﺜﺮوﻣﻴ ﺴﻴﻦ‬
‫أزﻳ‬ ‫ﺑﻼزﻣﺎ‬
‫اﻟﻤﻴﻜﻮ‬ ‫ص )‪450‬‬
‫ﺜﺮوﻣﻴ ﺴﻴﻦ‬
‫ﻛﻼرﻳ‬

‫ﺑﺢ‬
‫اﻟﻜﻠﻮراﻣﻔﻴﻨﻴﻜﻮل )ﻛﺎ‬ ‫اﻟﻜﻠﻮراﻣﻔﻴﻨﻴﻜﻮل‬ ‫ح اﻻﻧﻔﻠﻮﻧﺰا‬ ‫ﺴﺠ ﻲ‬
‫ﻓﻘﺮ دم ﻻﺗﻨّ‬
‫ﺛﻴﻢ(‬
‫ﻟﻠﺠﺮا‬ ‫ﺛﻮﻣ ﻲ‬
‫ﺘﻬﺎ ب اﻟ ﺴﺤﺎﻳﺎ اﻟﺠﺮ‬
‫اﻟ‬ ‫ﺘﻼزﻣ ﺔ اﻟﻄﻔﻞ اﻟﺮﻣﺎدي‬
‫ﻣ‬
‫ﺧﺮاﺟﺎ ت اﻟﺪﻣﺎغ‬

‫ﺒﻂ‬
‫ﺜ‬‫ﺛﻴﻢ‪:‬ﻳ‬
‫ﺒﻂ ﻟﻠﺠﺮا‬
‫ﺜ‬‫ﻟﻴﻨﻜﻮﺳﺎﻣﻴﺪ )ﻣ‬ ‫اﻟﻜﻠﻴﻨﺪاﻣﺎﻳ ﺴﻴﻦ‬ ‫ﺘﻴﺮوﻳﺪﻳﺰ اﻟﻬﺸ ﺔ‬
‫ﺑﺎﻛ‬ ‫ﺘﻬﺎ ب اﻟﻘﻮﻟﻮن اﻟﻐﺸﺎﺋ ﻲ اﻟﻜﺎذ ب‬
‫اﻟ‬

‫ﺘﺪاﺧﻞ ﻣﻊ ﻣﺮﻛ ﺐ‬
‫ﺘﻴﺪﻳﻞ ﻋﻦ ﻃﺮﻳﻖ اﻟ‬
‫ﺒ‬‫ﺒ‬‫ﺗﺮاﻧ ﺴﻔﻴﺮاز اﻟ‬ ‫ﺗﻘﺎﻟﻴ ﺔ‬
‫ﺒﺮ‬‫ﺘﺮﻳﺎ اﻟﻤﻜﻮرة اﻟﻌﻨﻘﻮدﻳ ﺔ اﻟ‬
‫ﺑﻜ‬
‫رد ﻓﻌﻞ ﻓﺮط اﻟﺤ ﺴﺎﺳﻴ ﺔ‬
‫أﻣﻴﻨﻮ أﺳﻴﻞ‪tRNA)-‬‬ ‫ﺜﺮ‬
‫ﺘﺨ‬‫ﺒﻴ ﺔ اﻟ‬
‫ﺘﻴﺮﻳﺎﺳﻠ‬
‫ﺒﻜ‬‫اﻟﻤﻜﻮرا ت اﻟﻌﻨﻘﻮدﻳ ﺔ واﻟ‬
‫ﺘﺎز‬
‫ﺘﺮاق اﻟﻌﻈﺎم ﻣﻤ‬
‫اﺧ‬

‫ﻟﻴﻨﺰوﻟﻴﺪ‬ ‫ﻟﻴﻨﺰوﻟﻴﺪ‬ ‫ﺑﻴ ﺔ اﻟﺠﺮام‬

‫ﻣﻘﺎوﻣ ﺔ إﻳﺠﺎ‬
‫ﺘﻐﻴﺮ(‬
‫)ﻣ‬

‫ﺘﻮﺟﺮاﻣﻴﻦ‬
‫ﺑ‬‫ﺘﺮ‬
‫اﻟ ﺴ‬ ‫ﺘﻴﻦ‬
‫ﺑﺮﻳ ﺴ‬
‫ﻛﻮﻳﻨﻮ‬ ‫ﺣﻘﻴﻘ ﻲ‬

‫ﺘﻴﻦ‬
‫ﺑﺮﻳ ﺴ‬
‫داﻟﻔﻮ‬ ‫ﺒﻴ ﺔ‬
‫ﺗﺠ ﺔ ﻋﻦ اﻟﻐﺎزا ت واﻟﻤﻜﻮرا ت اﻟﻌﻨﻘﻮدﻳ ﺔ اﻟﺬ ﻫ‬
‫ﺑﺎ ت اﻟﺠﻠﺪﻳ ﺔ اﻟﻨﺎ‬
‫ﺘﻬﺎ‬
‫اﻻﻟ‬
 ‫ﺒﻄﺎ تﺗﺨﻠﻴﻖ اﻟﺤﻤﺾ اﻟﻨﻮوي‬
‫ﺜ‬‫ﻣ‬
‫‪Machine Translated by Google‬‬

‫اﻟﻔﻠﻮروﻛﻴﻨﻮﻟﻮﻧﺎ ت‬
‫ﺒﻂ إﻧﺰﻳﻢ ﺟﻴﺮاز اﻟﺤﻤﺾ اﻟﻨﻮوي‪ ،‬وﻳﻤﻨﻊﺗﺨﻠﻴﻖ اﻟﺤﻤﺾ اﻟﻨﻮوي(‬
‫ﺜ‬‫ﺛﻴﻢ‪:‬ﻳ‬
‫ﺒﻴﺪ ﻟﻠﺠﺮا‬
‫)ﻣ‬

‫اﻟﺠﻴﻞ اﻷول‬ ‫ﺣﻤﺾ اﻟﻨﺎﻟﻴﺪﻳﻜ ﺴﻴﻚ‬ ‫ﺲ‬

‫ﺋﻴ ﺔ‬ ‫ﺘﻮﻛﻮﻛ‬
‫اﻟﻀﻮ‬ ‫ﺒ‬‫ﺘﻴ‬
‫ﺴﻤﻴ ﺔ‬‫ﺳ‬‫اﻟ‬
‫اﻟﻌﺮﻗﻮ ب‬ ‫ﺗﺮ‬
‫اﻟﻤﻴﻜﻮو‬
‫ﺑﻼزﻣﺎ‬ ‫ﺗﻤﺰق‬
‫ﺷﻔﺎء ‪+‬‬
‫اﻟﻜ ﺴﻮر‬ ‫اﻟﻬﻮاﺋﻴ ﺔ‬
‫ﺿﻌﻒ‬‫ﻏﺮام‬

‫ﺜﺎﻧ ﻲ‬
‫اﻟﺠﻴﻞ اﻟ‬ ‫ﺒﺮوﻓﻠﻮﻛ ﺴﺎﺳﻴﻦ‬
‫ﺳﻴ‬ ‫ﻛﻤﺎ ﻫﻮ ﻣﺬﻛﻮر أﻋﻼه ‪+‬اﻟﺰاﺋﻔ ﺔ‬ ‫ﻋﲆ اﻟﻨﺤﻮ اﻟﻮارد أﻋﻼه‬

‫اﻟﻨﻮرﻓﻠﻮﻛ ﺴﺎﺳﻴﻦ‬
‫إﻧﻮﻛ ﺴﺎﺳﻴﻦ‬
‫أوﻓﻠﻮﻛ ﺴﺎﺳﻴﻦ‬
‫ﻟﻴﻔﻮﻓﻠﻮﻛ ﺴﺎﺳﻴﻦ‬

‫ﺜﺎﻟ ﺚ‬
‫اﻟﺠﻴﻞ اﻟ‬ ‫ﺗﻴﻔﻠﻮﻛ ﺴﺎﺳﻴﻦ‬
‫ﺟﺎ‬ ‫ﺑﻴ ﺔ اﻟﺠﺮام‬
‫ﻛﻤﺎ ﻫﻮ ﻣﺬﻛﻮر أﻋﻼه ‪+‬إﻳﺠﺎ‬ ‫ﻋﲆ اﻟﻨﺤﻮ اﻟﻮارد أﻋﻼه‬

‫ﺑﻊ‬
‫اﻟﺠﻴﻞ اﻟﺮا‬ ‫ﻣﻮﻛ ﺴﻴﻔﻠﻮﻛ ﺴﺎﺳﻴﻦ‬ ‫ﺑﻴ ﺔ اﻟﺠﺮام ‪+‬اﻟﻼ ﻫﻮاﺋﻴ ﺔ‬
‫ﻛﻤﺎ ﻫﻮ ﻣﺬﻛﻮر أﻋﻼه ‪+‬إﻳﺠﺎ‬ ‫ﻋﲆ اﻟﻨﺤﻮ اﻟﻮارد أﻋﻼه‬

‫ﺟﻴﻤﻴﻔﻠﻮﻛ ﺴﺎﺳﻴﻦ‬
‫‪Machine Translated by Google‬‬
‫ﺒﻄﺎ ت اﻟﺤﻤﺾ اﻟﻨﻮوي اﻷﺧﺮى‬
‫ﺜ‬‫ﻣ‬

‫ﺛﻴﻢ‪:‬ﺗﻌﻄﻞ‬
‫ﺒﻴﺪ ﻟﻠﺠﺮا‬
‫ﺘﺮوﻧﻴﺪازول )ﻣ‬
‫ﻣﻴ‬ ‫اﻟﻼ ﻫﻮاﺋﻴ ﺔ‬
‫ﺘﺮوﻧﻴﺪازول )ﻓﻼﺟﻴﻞ(‬ ‫ﻣﻴ‬ ‫ﺑﺎ ت‬
‫اﻟﻨﻮ‬
‫ﺜﻨﺎﺋﻴ ﺔ‬
‫ﺘﺠﺎ ت اﻷﻳﻀﻴ ﺔ اﻟ‬
‫اﻟﻤﻨ‬ ‫ﺒﻴﻠ ﻲ‬
‫ﺧﻠﻞ وﻇﻴﻔ ﻲ ﻛﺮﻳ‬
‫اﻟﺤﻤﺾ اﻟﻨﻮوي(‬
‫ﺗﻔﺎﻋﻞ دﻳ ﺴﻔﻠﻔﺮام ‪ETOH‬‬

‫ﺒﻮزي ‪(RNA).‬‬
‫ﺒﻄﺎ تﺗﺨﻠﻴﻖ اﻟﺤﻤﺾ اﻟﻨﻮوي اﻟﺮﻳ‬
‫ﺜ‬‫ﻣ‬

‫ﺛﻴﻢ‪:‬ﻳﻤﻨﻊ ﻧ ﺴﺦ‬
‫ﺒﻴﺪ ﻟﻠﺠﺮا‬
‫ﺒﻴﻦ )ﻣ‬
‫رﻳﻔﺎﻣ‬ ‫اﻟﺠﺔ ﺴﻢ‬ ‫ﺒﻴﻦتﺳﻮاﺋﻞ‬
‫اﻟﻌﻨﻘﻮدﻳ‬ ‫ﻟﻮن‬‫ﻳﻔﺎﻣ‬‫ر‬
‫ﺗﻐﻴﺮ‬
‫اﻟﻤﻜﻮرا‬
‫ﺒﻴﻂ‬
‫ﺜ‬‫ﺒ ﻲ ﻋﻦ ﻃﺮﻳﻖﺗ‬
‫اﻟﺤﻤﺾ اﻟﻨﻮوي اﻟﺮﻳ‬ ‫ﺴﻞ()‪INH‬‬
‫)اﻟ )ﻣﻊ‬
‫ﺒﺪ‬ ‫اﻟﻜ‬
‫ﺘﻔﻄﺮة‬
‫ﺳﻤﻴ ﺔ‬
‫اﻟﻤ‬
‫ﺒ ﻲ(‬
‫ﺑﻮﻟﻴﻤﻴﺮاز اﻟﺤﻤﺾ اﻟﻨﻮوي اﻟﺮﻳ‬
‫ﺒﻄﺎ تﺗﺨﻠﻴﻖ أﺣﻤﺎض اﻟﻔﻄﺮﻳﺎ ت‬
‫ﺜ‬‫ﻣ‬
‫أﻳﺰوﻧﻴﺎزﻳﺪ‬ ‫أﻳﺰوﻧﻴﺎزﻳﺪز‬ ‫اﻟ ﺴﻞ‬

‫اﻟ ﺴﻞ اﻟﻜﺎﻣﻦ‬
‫ﺒﻄﺎ تﺗﺨﻠﻴﻖ ﺣﻤﺾ اﻟﻔﻮﻟﻴﻚ‬
‫ﺜ‬‫ﻣ‬

‫ﺴﺎزت‬
‫ﺴﻠﻔﻮﻧﺎﻣﻴﺪا‬
‫ﺜﻮﻛ‬‫ﺳﻠﻔﺎﻣﻴ‬
‫ﺒﻮﻟﻴ ﺔ‬ ‫اﻟﺼﻔﻴﺤﺎ‪ /‬اﻟت‬
‫ﺴﺎﻟﻚ اﻟ‬ ‫ﻳﻢ‬
‫ﺑﺮ اﻟﻤ‬
‫ﺜﻮ ب‬‫ﻳﻤﻴ‬
‫ﺔ اﻟ‬
‫ﺘﻬﺎ‬ ‫ﺋﻦ‬‫ﺗﺮ‬
‫ﻗﻠ‬
‫ﻛﺎ‬
‫اﻟﺤﻤﻞ‬
‫ﻣﻦ)‪(SMX‬‬ ‫ﺜﺎﻟ ﺚ‬
‫أوﻟ ﻲ‬ ‫ﺒﻴﻂ اﻟﻣﻊ‬‫ﺗﻴﻮساﻟ‬
‫ﺜﻠ ﺚ‬
‫ﺜ‬ ‫ﺛﻴﻢ‪:‬ﻲ‬
‫ﺗ‬ ‫ﺒﻪ ﻓ‬‫ﺑﺮو‬
‫ﺗﺠﻨ‬
‫)ﺟﺮا‬
‫ﺴﻮﻛ ﺴﺎزول‬ ‫ﺳﻠﻔﻴ‬
‫اﻟﻤﻌﻮﻳ ﺔ‬
‫ﺑﺎ(‬
‫ﺑﺎ‬
‫ﺳﻠﻔﺎدﻳﺎزﻳﻦ‬

‫ﺜﺎﻣﻴﻦ‬
‫ﺑﻴﺮﻳﻤﻴ‬ ‫ﺜﺎﻣﻴﻦ‬
‫ﺑﻴﺮﻳﻤﻴ‬ ‫ﻣﻼرﻳﺎ‬
‫ت‪ .‬ﺟﻮﻧﺪي‬
Machine Translated by Google
Machine Translated by Google

‫ﺷﻜ ﺮًا ﻟﻚ‬