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INTRODUCTION TO ANIMAL NUTRITION NUTRIENT BALANCE

- difference between the supply


FEED (intake + endogenous production) of
- animal feed a nutrient and its loss from the body
- source of nutrients for animals - ‘balance’ sometimes means
- ingredient of diets equilibrium but sometimes gain
(positive balance) or loss
NUTRITION (negative balance)
- process of providing and obtaining - most easily applied to nutrients that
the food necessary for the health are not produced or destroyed in
and growth of animals metabolism
- utilized as the main energy source Example:
by an animal through various - Measure the balance of elements
processes such as sodium, carbon, or nitrogen
from deducting from intake the sum
NUTRIENT of the losses in feces, urine, swear,
- substance in the diet that is expired air, etc.
physiologically useful in cellular,
animal and plant metabolism NUTRIENT REQUIREMENTS
- essential nutrients are that can only - least required quantities of nutrients
be acquired from the diet (energy, protein, fat, minerals, and
vitamins) needed to fulfill an animal’s
Examples: actual requirement
- Water
- Amino acids in proteins NUTRITIVE VALUE
- Carbohydrates - amount of nutrients contained in a
- Fats feed that can be utilized by the
- Vitamins animal
- Macrominerals
- Trace minerals
NUTRIENTS
- Ultra-trace minerals

Carbohydrates Protein ESSENTIAL NON-ESSENTIAL

Fat Minerals Necessary in the Not required in the


diet as the body diet since the body
Vitamins Water cannot produce produces it
*the basic nutrients that animals require for them in sufficient internally.
quantities to meet
maintenance, growth, reproduction, and
metabolic
good health. requirements

RATION
- amount of feed an animal receives in
a 24-hour period
BALANCED RATION
- amount of feed that will supply the
DIGESTION
proper amount and proportions of
nutrients needed for an animal to
perform a specific purpose
MECHANICAL CHEMICAL MICROBIAL

IMPORTANCE OF UNDERSTANDING - Mastication - Enzymes - Action of


ANIMAL NUTRITION - Muscular secreted in bacteria,
- nutrition drives the profitability of contractions various protozoa,
production animal enterprises. of the digestive and fungi
alimentary juices
*more than 60% of the variable costs of
canal
production in intensive animal production
enterprises are feed-related. CLASSIFICATION OF DIGESTIVE
- poor nutrition (underfeeding, nutrient SYSTEM
imbalances or overfeeding) is a key
determinant of animal health. ● Anatomy of Digestive Tract
*inappropriate diets are major causes of
health and welfare problems. I. Non-Ruminant
- animal nutrition has large effects on
the environment.
*nearly all of the negative impacts of Monogastric Simple stomach, Dogs, cats, minks,
animals on the environment are related to non-functional pigs, catfish
cecum
nutritional management in some way.
- the global animal feed industry is Functional Nonruminant Horse and Rabbits
large and growing. Cecum herbivore
*as the per capita income of countries
increases, so does their consumption of II. Ruminant
animal proteins. - Complex stomach
___________________________________ - Cattle, goats, sheep, buffaloes,
DIGESTIVE SYSTEM AND DIGESTIVE camels
TRACT PHYSIOLOGY III. Avian
- Chicken, ducks, turkeys
DIGESTION VS ABSORPTION
- Digestion is about breaking down ● Primary Type of Feed and their
food, while absorption is about Feeding Behavior
taking the useful parts into the body
for use. I. Carnivores
- ingestion-> digestion-> absorption-> - Dogs and cats
elimination - Short and simple
organization of GIT
(gastrointestinal tract)
II. Herbivores
- Cattle and horse
- Eat only plant materials - Some microbial fermentation
which are not readily occurs in colon
digestible
- Have long and large GIT with THE ALIMENTARY CANAL
complex and modified parts - Function:
III. Omnivores ● Prehension
- Pig and man ● Ingestion
- Have GIT intermediate of ● Comminution
those carnivores and ● Digestion
herbivores anatomically and ● Absorption
efficiency in utilizing fibrous ● Elimination
plants - Movement of the intestinal contents
IV. Granivores along the tract is produced by
- Also known as grain feeders peristaltic waves – contractions of
- Large proportion of their the circular muscle of the intestinal
feeds consist of plant wall.
seeds/grains/cereals having
very high energy content ● MOUTH
- No teeth, but having unique - Mainly mechanical,
specialized GIT to digest mastication helping to break
grains up large particles of food and
mix it with saliva which acts
● Location of Sites of Microbial as a lubricant and for taste
Fermentation perception

I. Pregastric (foregut fermenters)


Lower Incisor Rooting
- Ruminants
- Predominant site of microbial Inward-curved Grasp and shear
fermentation preceding the upper incisor food items
stomach (gastric pouch) and
Premolars and Crush the food
small intestine
molars
- Hindgut fermentation also
occurs
II. Hindgut fermenters - The pig has taste buds
throughout the oral cavity
functional - Non-ruminant herbivores - Saliva is secreted into the
cecum - Predominant site of microbial
fermentation following the SI mouth by salivary glands
(small intestine) *Saliva = 99% water + 1% (mucin, inorganic
- Elephant, rhinoceros, horses, salts, and enzymes a-amylase and complex
and rabbits lysozyme)
III. Monogastric (non-functional cecum) - Horse, cat, and dog lack
- Carnivores salivary a-amylase
- Have no major specialized
site of microbial fermentation
*They rely more on the enzymatic activity of - Pyloric Region
amylase in the small intestine rather than in - has glands like cardia
the mouth region that secret protective
mucus
● STOMACH Gastric Juice is made up of:
- Stomach of an adult pig has - water
a capacity of 8L -pepsinogens
- Simple compartment – -inorganic salts
digestion and storage -mucus
- -hydrochloric acid
-intrinsic factor for absorption of Vit
B12

Cardio
Cephalic Phase Stimuli such as
sight and smell of
food act via vagus
nerve

Gastric Phase Secretion is


maintained by
chemical sensors
and distention of
stomach

Presence of Elicits secretion by


Digesta neural and
hormonal
messages
- Esophageal Area
- no glands ● SMALL INTESTINE
- a-amylase activity may continue - Duodenum (mixing digesta
- active microbial population and secretions), jejunum
- Cardia (absorption), and ileum –
- secretes alkaline, enzyme-free, main absorption site
viscous mucus formed of a - Duodenal (Brunner’s) gland
gel-forming glycoprotein that = produce an alkaline
protects epithelium from acid attack secretion that acts as a
- Gastric Glands lubricant and protects
- secretes glycoprotein duodenal wall from HCL acid
and fucolipid mucus and entering from the stomach.
contains oxyntic cells = - Bile Salts play an important
produce HCL til It chloric acid
'

role in digestion by activating


- produces pepsinogen pancreatic lipase and
emulsifying fats
Pancreatic lipase is responsible for - Raw potato starch is
breaking down fats resistant to hydrolysis by
- works more efficiently on amylase.
smaller fat droplets - Lignin – indigestible
- emulsification facilitated by
bile salts aids in fat
breakdown
the 51in It - Contains villi – increase
? i

ii. at iii. e.
surface area for absorption
- Each villus contains an
Pina÷, '

arteriole and venule + lacteal

*gqg÷÷ALL
ribs UCOse
:b
-
-
-

kids
¥ initio
I
.

- Venules drain to hepatic


portal system
- Lacteal drain to the thoracic
¥-1? In t.iui.ir
-
v1

t.AE
.
I ?

1.1 thick to increase


.
lymphatic duct
diffusion i 1T¥ .
- Extensive microbial activity

-
lacteal
(tiny t.yvn-poi-t-ieii.es
el:D ● LARGE INTESTINE occurs
absorbs iffy c. id.

- Play an important role in the - Abundant nutrient sources


glycerol .

retrieval of nutrients, encourage growth of bacteria


electrolytes, and water in the - Complex population of
digesta aerobic and obligate
- Mucosal surface does not anaerobic bacteria
have villi but has small - Bacterial action in the large
projections that increase intestine may have beneficial
surface area effects on the synthesis of
some B vitamins.
- Synthesis of most vitamins in
the digestive tract of pigs is,
however, insufficient to meet
the daily requirements and a
dietary source is needed.

DIGESTION IN YOUNG PIG

- From birth until about 5


weeks of age the
- Cellulose and many of the concentration and activity of
hemicelluloses are not digestive secretions are
attacked by any of the different from adult animals.
enzymes present in the - During the first few days after
digestive secretions of the birth – intestine is permeable
pig. to native proteins
- Essential for the transfer of - Digestion in SI is similar to that in pg
y-globulins (antibodies) via ● SMALL INTESTINE
mother’s milk - Intestinal mucosa produces mucin,
- Piglet stomach initially a-amylase, maltase, sucrase, and
produces only a limited proteolytic enzymes
amount of HCL and - Chicks have maltase and sucrase
pepsinogen BUT it does activities in their SI – perform well on
secrete chymosin. diets containing uncooked cereals
Chymosin - Satisfactory amylase activity
- Clots milk thereby avoiding flooding ● CAECA
the small intestine with nutrients - Function as absorptive organs but
- As a piglet grows, pepsinogen and are not essential in fowls
HCL secretion increases ● COLON
- Transport of digesta to its
DIGESTION IN FOWL termination at the cloaca
- Lips and cheeks are replaced by
beak DIGESTION IN DOG AND CAT
- Teeth are absent - The saliva of dogs and cats has no
- Taste buds located on the back half a-amylase activity, as the natural
of the tongue diet is low in starch.
- Stomach secretes gastric lipase and
● CROP pepsin
- Diverticulum of the esophagus - Pepsin is most active when animals
- Reservoir for holding food ingest collagen ~ important in -
cats
- Filled and emptied by peristalsis digestion of meat; more important in
- Microbial activity occurs during cats.
storage of food - In dogs, gastric juice has
- Lactobacilli predominate adhering to antibacterial activity
-

dogs
the crop wall - Similar to pigs, young dogs and cats
● PROVENTRICULUS are less efficient in digesting solid
- Glandular stomach food than older animals.
- Produces HCl (hydrochloric acid)
and pepsinogen PRE-CAECAL DIGESTION IN HORSE
- Minimal inherent motility - Horses are herbivores with a simple
● GIZZARD stomach like pigs, but their hindgut,
- Muscular organ with internal ridges especially the caecum, is much
- Grinds the food with moisture – turns larger. This enlarged hindgut houses
it into a smooth paste microbial populations that aid in the
- Walls produces KOILIN – hardens digestion of plant materials.
the presence of HCl - Horses digest fibrous foods through
● PANCREAS a combination of enzymatic
- Pancreatic juices of fowls contain digestion before microbial
same enzymes as the mammalian fermentation. This places them
secretion between pigs and ruminants in terms
of their ability to break down fibrous 3. PINOCYTOSIS ‘CELL DRINKING’
materials. - Cells have the capacity to engulf
● STOMACH large molecules in solution or
- Primary role is to regulate flow of suspension.
digesta to the small intestine for - Important in newborn suckled
efficient digestion. mammals in which immunoglobulins
- Digesta retention time is short– present in colostrum are absorbed
grazing horses. intact.
● SMALL INTESTINE
- the main site for digestion of RUMINANT DIGESTION
non-fibrous carbohydrate, protein, - Stomach of ruminant is divided into
and fat. four compartments.
- Soluble carbohydrates are exposed 1. Rumen paunch
-

to pancreatic enzymes for digestion. 2. Reticulum honeycomb


-

● LARGE INTESTINE 3. Omasum many plies


-

- The microbes ferment fibrous 4. Abomasum true stomach


-

materials. - In young suckling- first two


● ABSENCE OF GALLBLADDER compartments are undeveloped.
- Horses lack a gallbladder and - Milk is channeled through the
cannot store bile esophageal/reticular groove to reach
- HCL acid in the duodenum the 3rd and 4th compartment
stimulates bile secretion from the (omasum & abomasum)
liver. - Fermentation of food by microbes in
rumen produces VOLATILE FATTY
ABSORPTION OF DIGESTED NUTRIENTS ACIDS.
Butyric acid = encourage formation
1. SMALL INTESTINE ADAPTIONS of papillae on the rumen wall.
- Specially adapted for absorption with - The gases are lost by eructation
increased inner surface area due to (belching) and the volatile fatty acids
folding and presence of villi. are mainly absorbed through the
- Duodenum has villi = mixing and rumen wall.
neutralizing - Microbes, along with undigested
- Jejunum – major site for absorption food parts, move to the abomasum
2. PASSIVE TRANSPORT AND and small intestine.
ACTIVE TRANSPORT - Releases enzymes to digest them,
- Nutrient absorption can occur by and the resulting breakdown
passive transport = simple diffusion products are absorbed.
when there is high concentration of - The produced volatile fatty acids are
nutrients outside the cell taken in, but the microbial cells,
- Active transport involves carriers along with undigested food parts,
with specific binding sites for are expelled in the feces.
nutrients and ions (Na or H) to
transport nutrients into cells against RUMINATION CYCLE
concentration gradients. 1. Regurgitation spit -
back up
2. Remastication -
chewing again
3. Reinsalivation-
mix with saliva

4. Redeglution - swallowing again


- In grazing cattle it is commonly
about 8 hours per day, or about
equal to the time spent in grazing.
- Each bolus of food regurgitated is
chewed 40– 50 times and thus
receives a much more thorough
mastication than during eating.

DIGESTION OF CARBOHYDRATES Pyruvate undergoes fermentation by


- The breakdown of carbohydrates in microbes. This fermentation process leads
the rumen is divided into 2 stages to the formation of acetate, butyrate, and
1. Digestion of complex propionate. These are short-chain fatty
carbohydrates to simple acids that serve as energy sources for the
sugars ruminant. The microbes in the stomach
2. Metabolism of carbohydrates transform pyruvate into these fatty acids,
providing the ruminant with nutrients
essential for its nutrition.

An excess accumulation of pyruvate can


contribute to the development of acidosis in
- > pamaol
the body. In conditions such as lactic
acidosis, pyruvate is converted into lactic
acid, leading to an increase in acidity. This
disturbance in the body's acid-base balance
can have detrimental effects on cellular
function and overall physiological
Cellulose and starch are both complex processes.
carbohydrates. Enzymes break down starch
into glucose molecules through a process - The most crucial digestive process
called glycolysis. However, cellulose, a in the rumen is the breakdown of
component of plant cell walls, requires cellulose and other tough
specialized enzymes to be converted into polysaccharides.
glucose. Through fermentation, these - This process not only provides
glucose molecules are transformed into energy for the ruminant but also
pyruvate, a key intermediate in cellular ensures that other nutrients, which
energy production. might otherwise escape digestion,
are exposed to enzyme action.
- The large rumen, making up 10-20%
of a ruminant's weight, gives enough
space for food to gather. This allows
ample time for the gradual
breakdown of cellulose, which takes BASIC NUTRIENTS AND FUNCTION
place at a slower pace in the rumen.
WATER
DIGESTION OF PROTEINS - Major item in most animal’s diet
- Water content of animal body varies
with age:
RUMEN RUMEN
DEGRADABLE UNDEGRADABLE New Born 750-800g per kg
PROTEIN (RDP) PROTEIN (RUP or
BYPASS) Mature Fat 500g per kg

- Microbes in the - Some dietary


rumen break proteins in FUNCTIONS OF WATER
down protein the rumen 1. Acts as solvent for nutrient transport
into small remain and waste excretion
peptides, unbroken. 2. Involved in enzyme-mediated
amino acids, This is useful chemical reactions like hydrolysis
and ammonia. when the
3. Contributes to the regulation of body
These animal's
products are protein/amin temperature
then utilized by o acid needs
the microbes are not met SOURCES OF WATER
to create through 1. Drinking water
microbial microbial - Poor water quality will
proteins within fermentation negatively impact the
the rumen. or the
formation of animal’s intake and reduce
new performance.
proteins. -
2. Water in food
- Water content of foods varies
DIGESTION OF LIPIDS
- Ranges from 60g/kg in
- Rumen microorganisms have a
concentrates to over 900g/kg
limited ability to digest lipids.
in some root crops
- Ruminant diets usually have low lipid
3. Metabolic water
content (around 50 g/kg). If the lipid
- Formed during metabolism
level goes above 100 g/kg, it can
by the oxidation of hydrogen
decrease the activities of rumen
containing organic nutrients
microbes.
- Calcium salts of fatty acids don't
WATER REQUIREMENT
impact rumen fermentation much;
- Expected water consumption of
they are used as fat supplements for
various species of adult livestock in
ruminants.
a temperate climate
2. Converted into glycogen
ANIMAL LITERS/DAY
3. Converted into fats as energy
2

Beef Cattle 22-66 reserve


1 highest 4. Accessory functions: milk and egg
Dairy Cattle 38-110 production
Sheep & Goats 5
4-15 5. As a source of fiber (esp. ruminant)
3
Horses 30-45 CLASSIFICATIONS OF CHO
4
Swine 11-19 SUGARS
7
lowest
Chickens 0.2-04
● MONOSACCHARIDES
6
Turkeys 0.4-0.6
HEXOSES
- Water requirements are increased in
cold weather because feed intake is 1. GLUCOSE
increased. - dextrose/ grape sugar/ corn sugar
- Animals are more sensitive to lack of - plants, fruits, honey, blood, lymph,
water than food. and CSF ( cerebrospinal fluid )
- Restriction of water = reduced intake - Major component of many
in feed oligosaccharides, polysaccharides,
- Severe restriction of water intake will and glucosides
result in rapid weight loss and body - White crystalline solid
dehydrates. - Soluble in water

FACTORS AFFECTING WATER INTAKE 2. D-FRUCTOSE


- Fruit sugar/ laevulose
● DIETARY FACTOR - green leaves, fruits, and honey.
- High level of protein intake - Occurs in the disaccharide sucrose
and fats may increase water and in fructans
intake - White crystalline solid has sweeter
- consumption of salt taste than sucrose
increases consumption and - Sweet taste of honey is due to this
excretion sugar
● ENVIRONMENTAL FACTOR 3. D-MANNOSE
- Heat stress - Does not occur free in nature
- exists in polymerized form as
CARBOHYDRATES MANNAN.
- Neutral chemical compounds - Component of glycoproteins
containing carbon, hydrogen, and
C H
- Widely distributed in yeasts, molds,
oxygen.
O
and bacteria.
4. D-GALACTOSE
FUNCTIONS OF CHO - Does not occur free in nature
1. Metabolize as source of energy
- breakdown product during - manufacturing beer and scotch malt
fermentation whisky
- Present as constituent of the - Water soluble but now as sweet as
disaccharide lactose – milk. sucrose
- Component of anthocyanin
pigments, galactolipids, gums, and GLUCOSE + GLUCOSE = MALTOSE
mucilages.
4. CELLOBIOSE
MONOSACCHARIDE DERIVATIVES - Does not exist naturally as a free
sugar
1. Phosphoric acid esters - Basic repeating unit of cellulose
2. Amino sugars – glucosamine and - Linkage cannot be split by
galactosamine mammalian digestive enzymes –
3. Deoxy sugars - DNA can be split by microbial enzymes
4. Sugar acids – Gluconic, glucaric,
and glucuronic acids GLUCOSE + GLUCOSE = CELLOBIOSE
5. Sugar alcohols
6. Glycosides TRISACCHARIDES

● OLIGOSACCHARIDE 1. RAFFINOSE
- small amounts in sugar beet and
DISACCHARIDES accumulates in molasses
- Cotton seed: 80 g/kg of raffinose
1. SUCROSE - Hydrolysis = glucose, fructose, and
- Most abundant occurring galactose
disaccharides in plants - main 2. KESTOSE
transport form of carbon - Occur in the vegetative parts and
- high concentration in sugar cane seeds of grasses
and sugar beet
- mangels and carrots and some fruits NON-SUGARS

GLUCOSE + FRUCTOSE = SUCROSE ● POLYSACCHARIDES

2. LACTOSE HOMOGLYCANS
- Mammary gland GLUCANS
- Cow’s milk contains 43-48 g/kg
lactose 1. STARCH
- Not soluble as sucrose - Reserve carbohydrates in plants
- Less sweet - Abundant in seeds, fruits, tubers,
and roots
GLUCOSE + GALACTOSE = LACTOSE - insoluble in cold water – suspension
in heated water
3. MALTOSE 2. GLYCOGEN
- Malt sugar
- Liver, muscles, and other animal - contains galactosamine in place of
tissues glucosamine
- Main carbohydrate storage product – - Sulfate esters of chondroitin are
energy metabolism major structural components of
3. DEXTRINS cartilage, tendons, and bones.
- Soluble in water and produce
gum-like solutions LIGNIN
- Give characteristic flavor to bread 1. LIGNIN
crust, toast, and partly charred foods - Not a carbohydrate
4. CELLULOSE - High resistance to chemical
- Fundamental structure of plant cell degradation
walls - Richly found in wood product,
- Found in nearly pure form in cotton mature hays, and straws

GLUCOSAMINES CARBOHYDRATES-RICH SOURCES


- Barley feed
1. CHITIN - Brown rice
- abundant in crustacean, fungi, and - Camote meal
some green algae. - Cassava meal
- Major structural component of the - Corn bran
exoskeletons of invertebrates. - Corn grain
- Corn grits
HETEROGLYCANS - Ground grain
- Sorghum
1. HEMICELLULOSE - Molasses
- Alkali-soluble cell wall - Rice bran
polysaccharides that are closely - Rice middling
associated with cellulose. - Rice polishing
- D-glucose + D-galactose + - Rough rice
D-mannose + D-xylose + - Sugar
L-arabinose units - Tallow
- fruit, plant, stems, and grain hulls - Vegetable fat
- Not digestible but can be fermented - Wheat bran
via microbial activity. - Wheat middling
2. HYALURONIC ACID - Pollard
- Contains acetyl-glucosamine
- skin, synovial fluid, and umbilical LIPIDS
cord - Insoluble in water but soluble in
- Solutions of this acid are viscous common organic solvents
and play important part in lubrication - Act as electron carriers, substrate
of joints carriers in enzyme reactions
3. CHONDROITIN
- Chemically similar to hyaluronic acid
CLASSIFICATION OF PLANT LIPIDS
FAT GLYCOGEN
1. STRUCTURAL LIPIDS
- present as constituents of various Energy yield 39 MJ/kg 17 MJ/kg DM
membranes and protective surface after oxidation DM
layers and make up about 7 per cent
Water content anhydrous Highly
of the leaves of higher plants. contains no water
:Ii I : iii.emical structure
i
hydrated

● SURFACE LIPIDS Stored energy 6x as


- mainly waxes, with relatively minor source effective
contributions from long-chain
hydrocarbons, fatty acids and cutin.
FUNCTIONS OF LIPIDS
● MEMBRANE LIPIDS
- present in mitochondria, the ANIMALS ANIMAL HUMAN
endoplasmic reticulum and the FEEDS FOOD
plasma membranes, are mainly
glycolipids (40–50 per cent) and -Dietary -Enhance -In beef,
phosphoglycerides. energy supply feed marbling is
-Source of appearance desirable –
heat, by improving interspersion
2. STORAGE LIPIDS insulation, color and of fat
- occur in fruits and seeds and are, and animal reducing particles in
predominantly, triacyl- glycerol. protection dust. lean meat
- identified almost 300 fatty acids -Carrier for
fat-soluble
Most abundant: a-linolenic acid vitamin
absorption
Most common saturated acid: Palmitic acid
-Act as
Most common monosaturated acid: Oleic electron
acid carrier
-Source of
CLASSIFICATION OF ANIMAL LIPIDS essential fatty
- Major energy storage – fats acid
- Fats in obese animals may be
contained in adipose tissue at ~97%
- Fat yield energy after complete NATURAL SOURCES OF LIPIDS
oxidation: 39 MJ/kg DM vs glycogen
17 MJ/kg DM ANIMAL PLANT NATURAL
BODY SOURCES

-Subcutaneous -Seed germ/ -Fat


-Surrounding embryo level-cereal
internal organs grains,
-Marbling and forages,
milk animal
products
- Oil seeds
CLASSIFICATION OF LIPIDS - Do not play an important role in
● GLYCEROL-BASED plants
1. FATS - When fatty acids combine with all
- Constituents of both plants and three alcohol groups, it forms a
animals substance known as triacylglycerol
- Important sources of stored energy or triglyceride.
- Fats and oils have the same general * If they have three identical fatty acid
structure but have different physical components – Simple Triacylglycerols
and chemical properties * More than one type of fatty acid is involved
Function: – Mixed triacylglycerols
- Supply energy
- Thermal insulator FATTY ACIDS
- Source of heat for maintaining body - are classified as:
temperature SATURATED - where there are only single
- hairless, hibernate, and bonds
cold-adapted animals have special UNSATURATED - where there are
deposits of ‘brown fat’ carbon-carbon double bonds
BROWN FAT * Unsaturated have lower melting points and
- Burning fat doesn’t produce energy are chemically more reactive
but releases heat instead. * Fatty acids with more than one double
- These tissues contain mitochondria bond are frequently referred to as
rich in respiratory carriers like polyunsaturated fatty acids (PUFA)
cytochromes – giving them a brown
color.

STRUCTURE OF FATS

GLYCERIDES OR ACYLGLYCEROLS
- Fatty acid esters of glycerol
- Referred to as neutral fats COMPOSITION OF FATS
- Accumulate in adipose tissue ● BUTYRIC ACID & CAPROID ACID
- Provide a means of storing fatty - Found in significant amounts
comes
acids –animals of milk fats of ruminants from animals
● CAPROIC ACID & CAPRYLIC ACID ESSENTIAL FATTY ACIDS (EFAs)
comes - Present in few oils like palm
from
plants kernel and coconut (lauric ● LINOLEIC (OMEGA-6) &
acid) a-LINOLENIC ACID
(OMEGA-3)
EXAMPLES OF FATS AND OIL SOURCES - Essential fatty acids
- Rape seed - Contribute to
- Soya bean membrane structure
- Rye grass - Play role in lipid
- Butter fat transport and specific
- Lard lipoprotein enzymes
- Beef tallow - Source materials for
- Menhaden synthesizing
- Cod liver eicosanoids (help
- Herring regulate functions:
blood clotting, blood
PLANT & MARINE OILS pressure, smooth
example is - More highly unsaturated (esp. muscle contraction,
fat from Bang fishes) – linoleic and linolenic acids
us immune response)

A.io?&.*iFH
- Fish and plant oils are softer and - Maintain fluidity of cell
remain in liquid form resembling true membranes
oils. SOURCES OF EFA
MAMMALIAN DEPOT FAT - Oilseeds are rich sources of linoleic
- Lower proportion of unsaturated fatty acid
acids - Linseed good source of a-linolenic
- Higher proportion of saturated fatty acids
acids – palmitic, stearic acids - Pigs and poultry consuming oilseed
- This composition makes animal fat residues –receive sufficient essential
firm and hard. fatty acids (EFAs) than ruminants.
DEFICIENCIES
SUBCUTANEOUS FAT 1. Growth retardation
- Contain higher proportion of 2. Increased permeability to water and
unsaturated acids increased water consumption
- Softer then deep-body fat 3. Increased susceptibility to bacterial
infections
4. Sterility
● Animals fats differ in texture 5. Less stable biomembranes
● Marine mammals have softer body 6. Capillary fragility
fat than land mammals. 7. Kidney damage, hematuria, and
● Animal fat needs to stay malleable at hypertension
tissue temperature influenced by 8. Decreased visual acuity
surroundings. 9. Decreased myocardial contractility
● Fats in colder parts (feet, ears) tend 10.Decreased ATP synthesis in liver and
to be more unsaturated heart
11.Decreased nitrogen retention 2. GLYCOLIPIDS
- Compounds consisting of a
PROPERTIES OF FATS carbohydrate bound to an alcohol
group of a lipid by glycosidic linkage.
● HYDROLYSIS - Location: Brain and Nerve fibers
- Achieved by boiling fats with
alkalis GALACTOLIPIDS
- Yields glycerol and soaps - Lipids of grasses and clovers –
- Termed “saponification” as it forms the major part of dietary fat of
produces sodium and ruminants
potassium salts of fatty acids - The fatty acids of the galactosidase
● LIPOLYSIS of grasses and clovers consist
- Process of fat breakdown largely of Linoleic and a-linolenic
under the influence of acids.
enzymes –lipases - Rumen microorganisms have the
- Products of lipolysis: ability to break down galactolipids,
● Mixtures of mono- resulting in the production of
and diacylglycerols galactose, fatty acids, and glycerol.
with free fatty acids - An initial stage of lipolysis is
● Butyric & Caproic necessary.
have strong tastes
and smells – 3. PHOSPHOGLYCERIDES
unacceptable to
consumers PHOSPHOLIPID
- Extensive lipolysis occurs in - Constituents of the lipoprotein
the duodenum during the complexes of biological membranes
absorption of dietary fats - Abundant in heart, kidneys, and
from the small intestine. nervous tissues
- Precedes the hydrogenation - Myelin sheath – 55% phospholipids
of fats in the rumen and the - Sources: eggs, soya beans
oxidation of fats in the body.
● ANTIOXIDANTS LECITHIN & CEPHALINS
- Vitamin E is a vital naturally - Play a role as emulsifying agents in
occurring antioxidant biological systems (duodenum)
- As an antioxidant, it plays a - White waxy solids that turn brown
crucial role in protecting when exposed to air (oxidation)
cells, including the lipids or ETHER PHOSPHOLIPIDS
fats within those cells, from - Form up to 50% of phospholipids of
damage caused by free heart tissue
radicals. - Platelet activating factor
electrons
↳ have unpaired ,

them highly
reactive &
making other
to interacting
with
prone
molecules in the body
● NON-GLYCEROL-BASED - Some 30% is in free state and the
1. SPHINGOMYELINS remainder is bound to lipoproteins.
- Important components of - Very insoluble – prolonged high
membranes – nervous tissue levels in blood result in deposition on
- Constitute up to 25% of total lipid in walls of blood vessels.
myelin sheath – protects nerve cells 2. 7-DEHYDROCHOLESTEROL
- Absent or low concentration in - Derived from cholesterol
energy-generating tissue - Important precursor of Vitamin D3
2. WAXES - Produced when sterol is exposed to
- Simple non-popular lipids ultraviolet light
- Water-insoluble, solid esters of long
chain fatty acid
- Solid at ordinary temperature but
soft and pliable when warm
- Widely distributed in plants and
animals – protective function
- Hydrophobic nature helps plants
reduce water loss from transposition,
while in animals, it gives wool and
feathers waterproofing
Lanolin - obtained from wool
Spermaceti - product of marine animals 3. ERGOSTEROL
(sperm whale) - Phytosterol
3. STEROIDS - Widely distributed in brown algae,
- Biologically important compounds bacteria, and higher plants
such as the sterols, bile acids, - Precursor of Ergocalciferol or
adrenal hormones, and sex vitamin D2
hormones.
PHYTOSTEROLS - plant BILE SALTS
=

19

MYCOSTEROLS - fungi i¥ - Synthesized from cholesterol


ZOOSTEROLS - animal ¥s÷ - Constitutes the major end point of
cholesterol metabolism
STEROLS - Under physiological conditions the
1. CHOLESTEROL acids exist as salts
- Zoosterol present in animal cells - Produced in liver, stored in
- Major sterol in human gallbladder and secreted into the
- Constituent of various biological upper small intestine
membrane and important in
myelinated structures of brain and IMPORTANCE
CNS 1. Main route for eliminating cholesterol
- Precursor of steroid hormones and 2. Prevent cholesterol crystallization in bile
bile acids with the help of
- Normal concentration in the blood phospholipids.
plasma: 1200-2200 mg/l
3. Aid in digesting dietary fats by AMINO ACIDS
emulsifying them for pancreatic - Produced when proteins are
lipase action. hydrolyzed by enzymes, acids, or
4. Potentially activate pancreatic lipase. alkalis
5. Help absorb fat-soluble vitamins from the - characterized by having a basic
digestive tract. nitrogenous group – amino group
and acidic carboxyl unit.
STEROID HORMONES
● ESTROGENS - female sex 20 COMMON AMINO ACIDS
hormones ● Monoamino-monocarboxylic acid
● ANDROGENS - male sex hormones 1. Glycine Giraffes
-

● PROGESTERONE - pregnancy 2. Alanine And


-

hormone 3. Valine -

Vampires

● CORTISOL, ALDOSTERONE, & 4. Leucine Love Licking


-

CORTICOSTERONE - produced in 5. Serine -


Soft

the adrenal cortex; control of 6. Threonine Tasty -

glucose and fat metabolism 7. Isoleucine Ice cream


-

● Sulphur-containing amino acid


8. Cysteine Crazy
-

9. Methionine MOFO -

PROTEINS ● Monoamino-dicarboxylic acids and


- Complex, high-molecular weight their amine derivatives
organic compounds 10. Aspartic acid All -

- Like carbohydrates and fats, they 11. Asparagine Ants


-

contain carbon, hydrogen, and 12. Glutamic acid Got -

oxygen – additionally contain 13. Glutamine Grapes


-

nitrogen and generally sulfur. ● Basic Amino Acids


- Principal constituents of organs and 14. Lysine- Love

soft structures 15. Arginine All


-

16. Histidine Heroes


-

FUNCTION ● Aromatic and Heterocyclic Amino


• Growth, repair, and maintenance of body Acids
structures and tissue 17. Phenylalanine Phineas -

• Body regulation 18. Proline Plays


-

• Catalysts (Enzymes) 19. Tyrosine Tennis


-

• Aid in maintaining fluid and electrolyte 20. Tryptophan Today -

balance
• Buffer system SPECIAL AMINO ACIDS
• Transport other substances through blood - Contain special amino acids that are
• Protection derivatives of common amino acids.
• Component of numerous body compounds ESSENTIAL AMINO ACIDS
• Source of energy - Plants and many microorganisms
can produce proteins from basic
nitrogen compounds like nitrates.
- Unlike animals, which cannot CLASSIFICATION OF PROTEINS
synthesize the amino group, they ● ACCORDING TO
need a dietary supply of amino acids COMPOSITION
to build body proteins. 1. SIMPLE PROTEINS
- Yield only amino acids upon
10 ESSENTIAL AMINO ACIDS hydrolysis
1. Arginine Hlssy fits
no
2. CONJUGATED PROTEINS
Phenylalanine Arguing 4
no

Valine 2. Histidine Lying


no
- Simple proteins + non-protein
""""" " 3. Isoleucine substances
BRANCHED
Threonine 4. Leucine i Live for this
" "" ""°

Isoleucine 5. Lysine acids

Methionine
6. Methionine
Histidine 7. Phenylalanine
Arginine 8. Threonine amino acids
Lysine
ketogenic
9. Tryptophan ↳ can be degraded
Leucine
10. Valine directly into acetyl-CoA

APPLICATION OF EAA
● ACCORDING TO SHAPE

*
Chick requirements 1. GLOBULAR PROTEINS
- Needs dietary supply of the 10 - Polypeptide chain coiled into
essential amino acids and require compact spherical shape
additional glycine - Soluble in water
Pig requirements - Mobile within cells
- Similar essential amino acid - Amylase, hemoglobin,
requirement but they can synthesize albumin, globulins
arginine 2. FIBROUS PROTEINS
Cat requirements - Polypeptide chains arranged
- Need dietary arginine due to their side-by-side in long filaments
- limited ability to synthesize ornithine - Insoluble in water
- Taurine is essential in their diet for - Mechanically strong
bile acid conjugation. - Structural and protective
Ruminant requirements function
- Can synthesize all essential amino - Collagen, elastin, keratin
acid through rumen microorganisms PROPERTIES OF PROTEINS
- Supply of amino acids from microbial ● DENATURATION
protein is limiting in quantity - All proteins can be denatured or
changed from their natural state.
PEPTIDES - Application of heat disrupts the weak
- Built up from amino acids by means noncovalent interactions holding
of peptide linkage protein structure.
- Significant for flavor and sensory - Acids, Alkalis, Alcohols, Urea, and
properties of foods such as yeast Salts of Heavy Metals induce protein
extract, cheese, and fruit juices.
denaturation by disrupting molecular heavy fertilization of fields with
interactions. manure or nitrogenous fertilizers,
contamination from septic tanks
NUCLEIC ACIDS ● ALKALOIDS
- High molecular weight compounds - Presence is restricted to a few
that play a fundamental role in living orders of the dicotyledons
organisms as a store of genetic - Have poisonous properties while
information others have desirable medical
- Means by which this information is properties.
utilized in the synthesis of proteins
- The main pyrimidines found in PROTEIN SOURCE: ANIMAL ORIGIN
nucleic acids are cytosine, thymine 1. Dried skimmed milk
and uracil. 2. Digester tankage
- Adenine and guanine are the 3. Tankage w/ bone
principal purine bases present in 4. Meat scrap or meat meal
nucleic acids. 5. Meat and bone scrap meal
6. Fish meal
OTHER NITROGENOUS COMPOUNDS 7. Hydrolyzed feather meal
8. Poultry by-product meal
● AMINES 9. Dried whole milk
- present in small amounts in most 10. Blood meal
plant and animal tissues PROTEIN SOURCE: PLANT ORIGIN
- Occur as decomposition products in 1. Soybean meal (SBM) (orig. Soybean
decaying organic matter and have oil meal)
toxic properties 2. Cottonseed meal (CSM)
● AMIDES 3. Peanut oil meal (POM) or peanut
- play an important role in 4. Meal (PNM)
transamination reactions 5. Linseed (oil) meal (LSM, LSOM, or
- Asparagine and Glutamine – LOM)
important derivatives 6. Corn gluten meal
- Urea – main end product of nitrogen 7. Brewer’s dried grains
metabolism in mammals 8. Distillers dried grains
- Uric acid – end product of purine 9. Copra meal
metabolism (birds) 10. Safflower meal w/o hulls
● NITRATES 11. Sesame oil meal
- present in plant materials, not toxic 12. Sunflower meal or sunflower oil meal
itself until converted to nitrite 13. Rapeseed meal (RSM)
- Oat hay poisoning (large amount of 14. Soybeans, cottonseed, and peanuts
nitrate in green oats)
● NITRATE ION VITAMINS
- One of the most common toxic - Essential and are supplied in the diet
substances in contaminated water (or microbial synthesis in digestive
- Sources is common in areas with a tract)
high concentration of animals –
- when absent or not properly VITAMINS AND BIOCHEMISTRY
utilized/absorbed – leads to
deficiency disease or syndrome PROVITAMINS (VITAMIN PRECURSORS)
- Substances that are chemically
DISCOVERY related to the biologically active form
of the vitamin but have no vitamin
1. Rats given diets with purified activity until the body converts it into
proteins, fats, carbohydrates, and active form. (e.g Vitamin D
inorganic salts. synthesis)
2. Results showed that diet of this type - Many vitamins are destroyed by
was inadequate for normal growth oxidation.
3. Small quantity of milk was added - Commercial vitamin preparations are
4. This proved that there was some dispersed in wax or gelatin
essential factors lacking in the pure
diet VITAMIN SUPPLEMENTATION OF DIETS

- The term ‘vitamines’ was derived Vitamin supplements must be;


from ‘vital amines’ ● free-flowing
- coined to describe these accessory ● non-dusty
food factors ● well-mixed with other diet
ingredients despite being added in
The word has been shortened to VITAMINS, small amounts.
a term that has been generally accepted as Some of these criteria are incompatible and
a group name. a compromise has to be reached.
● Oily vitamins are absorbed onto
- Vitamins are not merely building silica
blocks or energy-yielding ● Coated or micro-encapsulated
compounds but mediators of ● Antioxidants are added to prevent
biochemical pathways. breakdown
● Use of stable derivatives of vitamins
BIOLOGICAL ROLE
- Co-factors for enzymatic and Factors Affecting the Stability of Vitamin
biochemical reactions Activity in the Supplement:
- Improve immunity and prevent 1. Temperature
illness 2. Humidity
- Slow aging 3. Acidity/Alkalinity
- Added to the diet at higher levels in 4. Oxygen
order to enhance the quality of the 5. Ultraviolet light
animal product (Vitamin D – for 6. Presence of trace minerals
eggshell strength; Vitamin E – for 7. Physical factors
prolonging the shelf life of 8. Length of time the supplement is
carcasses) stored
VITAMIN GROUPS Role & metabolism:
"
"
Bone formation & CHO metabolism
Fat-soluble vitamins ADEK sago
● Vitamin A Deficiency disease/ symptoms:
Source: - In young animals - Rickets (weak
Accumulates in the liver; oils from livers of and easily broken bones; bowed
certain fish, egg yolk, milk fat; leafy forages; legs)
- In older animals – Osteomalacia
Present as precursors or provitamins in the - Poultry:
form of CAROTENOIDS – can be converted • soft and rubbery bones and beak
into the vitamin. B-carotene is the most • weak legs
important member. • retarded growth
• reduced egg production
Role & metabolism: • poor eggshell quality.
Vision
- Rhodopsin- photoreceptor for vision ● Vitamin E
at low light intensities. Source:seed germ or germ oils from plants,
Cellular Differentiation green forage or hay
- Formation and protection of
epithelial tissues and mucous A-tocopherol – most biologically active form
membranes.
Immune System Role & metabolism:
- Promotion of healing immune - Antioxidant
integrity - Development and functioning of
- Scavenger of free radicals. immune system
- Recent research suggests it is also
Deficiency disease/symptoms: involved in regulation cell signaling
- Cattle: roughened hair and scaly and gene expression
skin; eye issues Deficiency disease/symptoms
- Pigs: eye disorders; reproductive - Cattle: white muscle disease
issues; growth retardation - Lambs: stiff lamb disease
- Poultry: high mortality rates; reduced - Pigs: myopathy and cardiac disease;
egg production mulberry heart disease in growing
- Horse, Dogs & Cats: night blindness; pigs
susceptibility to infection - Chicks: myopathy;
encephalomalacia (crazy chick
● Vitamin D2 & D3 disease); exudative diathesis
Source: Halibut-liver and cod-liver oils, egg - Horses: “tying up” – lameness and
yolk, sun-cured hay muscle rigidity

Chemical transformation occurs in ● Vitamin K


the skin. Ergocalciferol (D2) and Source:most green leafy materials,
Cholecalciferol (D3) – most important forms. cabbage, kale, egg yolk, liver, and fishmeal.
Phylloquinone or Vitamin K1 – form - CHO and protein metabolism
of the vitamin present in plants.
Deficiency disease/symptoms:
Role & metabolism: - Pigs: poor appetite, growth
- Synthesis of prothrombin retardation, vomiting, skin eruptions.
- Blood clotting & eye abnormalities
- Chicks: ’curled toe paralysis’
Deficiency disease/ symptoms: - Breeding hen: ‘clubbed down’
- Cattle: associated with sweet clover - Horse: moon blindness
disease
- Chicks: anemia, delayed blood B3: Niacin/Nicotinamide
clotting Source: Nicotinic acid can be synthesized
from tryptophan in body tissues; liver; yeast;
Water-soluble Vitamins groundnut; sunflower meals
● Vitamin B complex
Role & metabolism:
B1: Thiamine - Constituent of coenzymes NAD and
Source: Green forage or well-cured hays, NADP
cereal grains (seed or brain), brewer’s yeast Deficiency disease/symptoms:
- 3D’s: dermatitis, diarrhea, and
Role & metabolism: dementia
- Oxidative decarboxylation of a-keto - Pellagra in humans
acids and pyruvate - Ulceration of the mouth, tongue, and
- Transketolase reactions digestive tract (black tongue in dog)
- Coenzyme– thiamine pyrophosphate
B5: Pantothenic acid
Deficiency disease/symptoms: Source: Liver, egg yolk, groundnuts, peas,
- Polyneuritis and convulsions (head yeast, and molasses; E. coli is known to
retraction in chickens) produce this vitamin
- Cardiovascular disturbance
- Beriberi – humans Role & metabolism:
- Anorexia and emaciation - Constituent of coenzyme A – fatty
acid oxidation, acetate metabolism,
B2: Riboflavin and cholesterol & steroid synthesis
Source: Green forages, hays, or silages;
Milk and milk products; Meat or fish meal; Deficiency disease/symptoms:
Yeasts - Pigs: slow growth, diarrhea, loss of
hair, scaliness of skin
Role & metabolism: - “GOOSE-STEPPING” gait
- Coenzyme – flavin mononucleotide - Chick: retarded growth, dermatitis
(FMN) and flavin adenine
dinucleotide (FAD)
- Involve in transport of hydrogen
(hydrogen receptor)
B6: Pyridoxine Deficiency disease/symptoms:
Source: Feedstuffs, cereal grains and - Chicks: Poor growth, anemia, and
by-products; rice and rice bran; yeasts; liver poor bone development
and milk - Poultry: Poor egg hatchability
- Symptoms rarely occur in other farm
Role & metabolism: animals
- Coenzyme – pyridoxal (active form)
- Amino acid absorption from the B12: Cyanocobalamin
intestine Source: Protein feeds of animal origin;
fermentation products
Deficiency disease/symptoms:
- Pigs: slow growth, diarrhea, loss of Role & metabolism:
hair, scaliness of skin - Ruminant- metabolism of propionic
- “GOOSE-STEPPING” gait acid into succinic acid
- Chick: retarded growth, dermatitis - Isomerization reactions

B7: Biotin Deficiency disease/symptoms:


Source: Liver, milk, yeast, oilseeds, and - Poultry: poor feathering and kidney
vegetables damage; hatching problems
- Anemia
Role & metabolism: - If low cobalt in diet = low B12
- Coenzyme- carbohydrate synthesis
from lactate, fatty acid synthesis, ● Choline
and conversion of propionate to Source: Green leafy materials, yeast, egg
succinyl-CoA yolk, and cereals; can be synthesized in the
liver from methionine
Deficiency disease/symptoms:
- Pigs: foot lesions, alopecia, and dry Role & metabolism:
scaly skin - Not a metabolic catalyst
- Poultry: reduced growth, dermatitis, - Essential as structural component of
leg bone abnormalities, poor body tissues
feathering, fatty liver and kidney - Lipid metabolism in liver
syndrome (FLKS) - Transmission of nerve impulse

B9: Folic Acid/Folacin Deficiency disease/symptoms:


Source: Green leafy materials, cereals, - Pigs and chicks: Slow growth and
oilseed meals fatty infiltration of liver
- Perosis or slipped tendon in chicks
Role & metabolism:
- Coenzyme in mobilization and ● Vitamin C – Ascorbic Acid
utilization of single-carbon groups Source: Citrus fruits and green leafy
- Synthesis of RNA, DNA, and vegetables
neurotransmitters
Role & metabolism: functions in protein synthesis (P, S,
- Oxidation-reduction mechanism Zn)
- Maintenance of collagen metabolism - Physiological: oxygen transport (Fe,
- Transport of iron ions Cu); fluid balance (Na, Cl, K);
- Antioxidant in conjunction with Vit. E acid-base balance regulation (Na,
Cl, K)
Deficiency disease/symptoms: - Catalytic: Activators and/or
- Scurvy – edema, emaciation, and components of enzyme systems
diarrhea (Ca, P, K, Mg, Fe, Cu, Mn, Zn);
- Failure in collagen formation – Mineral-vitamin relationship (Ca, P,
defects in bone, teeth, cartilage, Co, Se)
connective tissue, and muscles
SOURCES
UNITS OF MEASURE FOR VITAMIN - Plants and plant products form the
NUTRITION main supply of nutrients to animals,
and the composition of plants will
● International Unit (IU) influence the animal’s mineral
- Standard unity potency as defined intake.
by the International Conference for
Unification Formulae (CUF)
l ● Plant species – grasses vs. legumes
● Stage of maturity- young vs. old
MINERALS plants
- Many naturally occurring mineral ● Type of soil – pH and mineral
elements are found in animal content
tissues,but not all are considered ● Climate and season
essential for the animal's - Common sources of minerals used
metabolism. in mineral supplements are:
- The term 'essential mineral element' ● limestone for calcium
is reserved for those minerals ● dicalcium phosphate for phosphorus
proven to have a metabolic role in ● common salt for sodium
the body. ● calcined magnesite for magnesium

COMPARTMENT CLASSIFICATION OF MINERALS


- Minerals in the body are stored in
different compartments, each ● MAJOR MINERALS
serving a specific role and having 1. CALCIUM (Ca)
varying rates of interchange with the Source: milk, green leafy crops, legumes,
central reserve. and sugar beet pulp. Animal by-products
- Blood plasma – primary storage and (fishmeal)
interchange compartment.
Function:
FUNCTION • bone and teeth formation;
- Structural: skeletal formation and • blood coagulation;
maintenance (Ca, P, Mg, Cu, Mn); • muscle contraction;
• nerve function; Deficiency:
• milk production; - Hypomagnesemia
• egg shell formation - Tetany (hypomagnesemic tetany)

Deficiency: Toxicities:
- Hypocalcemia - Hypermagnesemia
- Young – rickets
- Adult- osteomalacia 4. SODIUM (Na)
- Poultry: thin-shelled eggs; reduced Source: animal products, marine origin.
egg production Common salt- most common.
- Cattle: milk fever, tetany
Toxicities: Function:
- Hypercalcemia • Osmotic regulation of body fluids
• Main inorganic cation of
2. PHOSPHORUS (P) extracellular tissue fluids
Source: milk, cereal grains, and fishmeal
products. Deficiency:
- Hyponatremia
Function: - Reduced growth
• bone and teeth formation; - Eye disturbances w/ corneal lesions
• Phosphorylation - Reproduction impairment
- Decreased osmotic pressure
Deficiency: (dehydration)
- Hypophosphatemia
- Same symptoms with calcium Toxicities:
deficiency - Hypernatremia
- Salt toxicity, blindness, nervous
Toxicities: disorders
- Hyperphosphatemia
- Urinary calculi – male ruminants 5. CHLORINE (Cl)
Source: pasture grass varies widely.
3. MAGNESIUM (Mg) Common salt – main source
Source: wheat bran, dried yeast, and most
vegetable protein concentrates. Clovers are Function:
richer in Mg than grasses. • Osmotic pressure
• Acid-base balance (chlorine shift)
Function: • HCl acid in digestion
• Enzyme activator – glycolytic
system Deficiency:
• Efficient metabolism of - Hypochloremia
carbohydrates and lipids - Vomiting and diarrhea
• Bone formation - Reduced growth
• Neuromuscular activity
Toxicities: unlikely
6. POTASSIUM (K) Deficiency: Anemia; thumps condition
Source: dried fruits, bananas, milk, and (labored & spasmodic breathing)
leafy greens
Excess:
Function: • Copper and phosphorus deficiencies
• Osmotic regulation • Nausea and vomiting
• Cations of cells • Oxidative stress & tissue damage
• Nerve and muscle excitability • death due to liver failure
• Carbohydrate metabolism
2. COPPER (Co)
Deficiency: Function: oxidation-reduction reaction;
- Hypokalemia hemoglobin synthesis; bone formation;
- Lethargic condition maintenance of myelin sheath; fur and wool
pigmentation.
Toxicities:
- Hyperkalemia Deficiency: Fading hair coat or lack of wool;
- Excess K = reduces Mg absorption nervous symptoms; swelling of joints;
anemia
7. SULFUR (S)
Source: occurs in proteins containing Excess: inhibits Cu utilization and storage
amino acids cystine, cysteine, and
methionine. 3. MOLYBDENUM (Mo)
Function: purine metabolism; stimulates
Function: microbial activity in rumen
• Amino acid composition
• Respiratory process Deficiency: lack of conversion of xanthine to
• Chondroitin sulphate – cartilage, uric acid
bone, tendons, and blood vessel
walls Excess: interferes with Cu activation of
• Wool enzymes; anemia and diarrhea

Deficiency: 4. ZINC (Zn)


- Primarily reduced growth effect due Function: cofactor of several enzyme
to sulfur amino acid requirement for systems; needed for bone and feather
protein synthesis development; immunity

Toxicities: unlikely Deficiency: poor hair or feather


development; poor FCR; parakeratosis in
● TRACE MINERALS swine; swollen hock syndrome in chicks

1. IRON (Fe) Excess: interferes with Cu metabolism and


Function: cellular respiration may cause anemia
(hemoglobin, cytochromes, myoglobin)
5. COBALT ( C )
Function: Component of vitamin B12

Deficiency: emaciation, anemia, and


listlessness

Excess: Unlikely

6. SELENIUM (Se)
Function: Protect against cellular
membrane damage by the peroxidases;
Related to that of Vit. E

Deficiency: Exudative diathesis (chicks);


White muscle disease (cattle); stiff lamb
disease (sheep); liver necrosis (pigs,
rats)

Excess: Acute toxicity

7. MANGANESE (Mn)
Function: oxidative phosphorylation;
amino acid metabolism; fatty acid
synthesis and cholesterol metabolism.

Deficiency: Poor growth; impaired


reproduction; perosis or slipped tendon
in poultry; head retraction in chicks

Excess: Unlikely

8. IODINE (I)
Function: Thyroxine formation (T3 and
T4); immune defense; reproduction

Deficiency: Goiter; stillbirths; hairless or


wool-less; abnormal estrous cycle

Excess:
• Lamb – reduced Ig and Vit E
absorption from colostrum
• Poultry – halt or slowed egg
production; delayed hatching

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