Name: Carinugan, Katrina Faye Marie D.

Section: BSPH3Y2-4
Dela Cruz, Einna Marie D.G. Date: December 13, 2013
Francisco, Nikka C. Group No: 2
Garcia, Carra Mia F.
Labrador, Christian A.

Group No.: 2
Manufacturer’s Name: DEGALAFRA Pharmaceuticals
Product Name: Sodium Bicarbonate Ear Drops
Potency: 1 g of NaHCO3/20ml
M.O Checked by:
Standard Order Quantity: 10 ml
Actual Order Quantity: 20 ml

Manufacturing Order Quantity: 6

Lot Number: PH3Y24-06
Manufacturing Date: December 13, 2013
Expiration Date:

Control Std. Weight Weight in

Raw Material(s) Weighed by Checked by
No. in grams grams
Sodium Bicarbonate 601 500 mg 10 g
Glycerol 602 3 mL 6 ml
Purified water qs ad 603

I. Weighing and Compounding Procedures:

COMPOUNDED BY CHECKED BY
1. Weigh _____ g of sodium bicarbonate.
2. Triturate the sodium bicarbonate into fine powder, if
Necessary.
3. Transfer the powdered sodium bicarbonate into
a 10 mL cylinder.
4. Dissolve sodium bicarbonate with 5.5 ml. Make
the volume up to 7 mL with water.
5. Add carefully 3 mL of glycerol into the dissolved
sodium bicarbonate. Transfer in a suitable container.

II.Product:
Description:
Quality control/ date: December 10, 2013

Preparation:
Label:
Insert:
Carton:

Computation:

Sodium Bicarbonate

5g x
=
10 ml 20 ml

x = 10 g

Glycerol

3 ml x
=
10 ml 20 ml

x = 6 ml

III. Give the use/s of the following raw materials

Raw Materials Use/s

Sodium Bicarbonate
Glycerol
Purified water
Questions:

1. Name some commercially available products similar to this preparation.

2. What is the methods used in preparing the solution?

3. What is eardrops?

4. What is the mechanism of action of the preparation?

5. Why is distilled water used for compounding?