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Chapter 4 Skin and Body Membranes
Chapter 4 Skin and Body Membranes
Lecture Presentation by
Patty Bostwick-Taylor
Florence-Darlington Technical College
▪Epithelial membranes
▪Cutaneous membranes
▪Mucous membranes
▪Serous membranes
▪Connective tissue membranes
▪Synovial membranes
Cutaneous
membrane
(skin)
Mucosa
Parietal layer
Serous fluid
Visceral layer
▪Synovial membranes
▪Loose areolar connective tissue only (no epithelial
tissue)
▪Line fibrous capsules surrounding joints
▪ Line bursae
▪ Line tendon sheaths
▪Secrete a lubricating fluid to cushion organs moving
against each other during muscle activity
Ligament
Joint cavity
(contains
synovial fluid)
Articular (hyaline)
cartilage
Hair shaft
Dermal papillae
Epidermis
Papillary Pore
layer Appendages of skin
• Eccrine sweat gland
Hypodermis
(subcutaneous
tissue)
Nervous structures Cutaneous vascular plexus
• Sensory nerve fiber
• Lamellar corpuscle Adipose tissue
• Hair follicle receptor
(root hair plexus)
▪Epidermis—outer layer
▪Capable of being hard and tough
▪Stratified squamous epithelium
▪Keratinocytes (the most common cell) produce a
fibrous protein called keratin
▪Avascular
▪Composed of five layers (strata)
▪Stratum granulosum
▪Stratum lucidum
▪Formed from dead cells of the deeper strata
▪Occurs only in thick, hairless skin of the palms of
hands and soles of feet
▪Stratum corneum
▪Outermost layer of epidermis
▪Shingle-like dead cells are filled with keratin (protective
protein prevents water loss from skin)
Desmosomes
Stratum spinosum. Cells contain thick
Epidermal bundles of intermediate filaments made
of pre-keratin.
dendritic cell
Melanocyte
Sensory Dermis
Merkel nerve
cell ending
© 2018 Pearson Education, Ltd.
Structure of the Skin
▪Melanin
▪Melanin is a pigment produced by melanocytes
▪Melanocytes are mostly in the stratum basale of the
epidermis
▪Color is yellow to brown to black
▪Melanin accumulates in membrane-bound granules
called melanosomes
▪Amount of melanin produced depends upon genetics
and exposure to sunlight
▪Dermis
▪Connective tissue
▪Underlies the epidermis
Epidermis
Papillary
layer
Dermis
Reticular
layer
Hair shaft
Dermal papillae
Epidermis
Papillary Pore
layer Appendages of skin
• Eccrine sweat gland
Hypodermis
(subcutaneous
tissue)
Nervous structures Cutaneous vascular plexus
• Sensory nerve fiber
• Lamellar corpuscle Adipose tissue
• Hair follicle receptor
(root hair plexus)
Sebaceous Eccrine
gland gland
Sebaceous
gland duct
Dermal connective
tissue
Hair in
hair follicle
Secretory cells
▪Eccrine glands
▪Open via duct to sweat pores on the skin’s surface
▪Produce acidic sweat
▪ Water, salts, vitamin C, traces of metabolic waste
▪Function in body temperature regulation
Eccrine
Sebaceous
gland
gland
Dermal connective
tissue
Eccrine
gland duct
Secretory cells
(b) Photomicrograph of a
sectioned eccrine
gland (205×)
© 2018 Pearson Education, Ltd.
Appendages of the Skin
▪Apocrine glands
▪Ducts empty into hair follicles in the armpit and
genitals
▪Begin to function at puberty
▪Release sweat that also contains fatty acids and
proteins (milky or yellowish color)
▪Play a minimal role in body temperature regulation
▪Hair
▪Produced by hair follicle
▪Root is enclosed in the follicle
▪Shaft projects from the surface of the scalp or skin
▪Consists of hard keratinized epithelial cells
▪Melanocytes provide pigment for hair color
▪Hair grows in the matrix of the hair bulb in stratum
basale
Hair
shaft
Arrector
pili muscle
Sebaceous
gland
Hair follicle
Hair root
Hair bulb
in follicle
▪Hair anatomy
▪Central medulla
▪Cortex surrounds medulla
▪Cuticle on outside of cortex
▪ Most heavily keratinized region of the hair
Cuticle
Cortex
Medulla
(b) Hair
Fibrous
sheath (dermal
connective Cuticle
tissue)
Hair Cortex
follicle
Epithelial
Medulla
root sheath
Melanocyte
Hair papilla
containing
blood vessels
Subcutaneous
adipose tissue
▪Nails
▪Heavily keratinized, scalelike modifications of the
epidermis
▪Stratum basale extends beneath the nail bed, which is
responsible for growth
▪Lack of pigment makes nails colorless
▪Parts of a nail
▪Free edge
▪Body is the visible attached portion
▪Nail folds are skin folds that overlap the edges of the
nail; the cuticle is the proximal edge
▪Root of nail is embedded in skin
▪Growth of the nail occurs from nail matrix
(a)
▪Burns
▪Tissue damage and cell death caused by heat,
electricity, UV radiation, or chemicals
▪Associated dangers
▪ Protein denaturation and cell death
▪ Dehydration and electrolyte imbalance
▪ Circulatory shock
▪Result in loss of body fluids and infection from the
invasion of bacteria
▪Malignant melanoma
▪Most deadly of skin cancers, but accounts for only 5
percent of skin cancers
▪Arises from melanocytes
▪Metastasizes rapidly to lymph and blood vessels
▪Detection uses ABCDE rule for recognizing melanoma
Totals
41/ 2 %
Anterior and posterior
head and neck, 9%
Perineum, 1%
9% 9%
100%
▪Skin cancer
▪Most common form of cancer in humans
▪Most important risk factor is overexposure to ultraviolet
(UV) radiation in sunlight and tanning beds
▪Cancer can be classified two ways
1. B enign means the neoplasm (tumor) has not spread
2. Malignant means the neoplasm has invaded other
body areas
(c) Melanoma