Disease Gram Morphology Virulence factor Other info

staining
Mycobacterium Tuberculosis Not obligate Acid-fast -Waxy surface
tuberculosis intracellular rod, long -ability to stimulate a strong
bacteria and thin cell-mediated immune response
(can be gram
negative)
Staphylococcus aureus Toxic shock Positive Cocci -produce coagulase, an enzyme
syndrome, scalded -grows in that coagulates plasma
skin syndrome, food clusters -hyaluronidase which digests
poisoning the intracellular glue
(gastroenteritis) (hyaluronic acid) that binds
connective tissue in host tissues
-staphylokinase, which digests
blood clots; a nuclease that
digests DNA (DNase)
-lipases that help the bacteria
colonize oily skin surfaces.
Clostridium tetani Tetanus Positive Rods Tetanospasmin exotoxin -anaerobic spore-bearing rods
- found in manured soils
-several of these had entered
their endospore phase,
assuming the characteristic
tennis racket-type morphology
Neisseria gonorrhea Gonorrhea; Negative cocci -Fimbrial adhesins
neonatal -antigenic variation,
conjunctivitis -IgA protease
(opthalmia -membrane blebs/endotoxin
neonatorium);
pelvic inflammatory
disease (PID)
Treponema pallidum Syphilis Not obligate -spirochete -binds by its hooked tip to the -Delicate flexible spiral
intracellular epithelium. At the binding site, filaments
bacteria the spirochete multiplies and
penetrates the capillaries -prepared using the modified
nearby. Within a short time, it steiner silver stain method
 (gram- moves into the circulation, and -spirochetes
negative cell the body is literally transformed
wall) into a large receptacle for
incubating the pathogen.
Virtually any tissue is a potential
target.

-T. pallidum produces no toxins

and does not appear to kill cells
directly.

Escherichia coli Neonatal meningitis Gram In uti- adhesins, motility -often called collectively
negative coliforms
-bacteria of the large intestine
In uti are responsible for producing
vitamins
-normally present in the
gastro-intestinal tract of man
and animals
-can cause wound and other
infections
Corynebacterium Diphtheria Positive Rods -Exotoxin encoded by a -club shaped
diphtheriae bacteriophage of C. -produce toxin which causes
diphtheria; diphtheria toxin diphtheria

Diphtheria- infection that

affects the upper respiratory
tract, where an inflammatory
exudate causes severe
obstruction to the breathing
airways, and sometimes
suffocation