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Name:

IRDAAFI
FAHRAHMAT_
105421111221

Exer
cise2:Skel
etal
Muscl
ePhy
siol
ogy
:Act
ivi
ty2:
TheEf
fectofSt
imul
usVol
tageonSkel
etal
Muscl
eCont
ract
ion
LabRepor
t

Pre-
labQui
zResul
ts
Youscored100%byanswer
ing4outof4quest
ionscor
rect
ly.

1. Skel
etalmusclefi
bersarei
nner
vated(st
imul
ated)
by
Youcor rect
lyanswered:
c.motorneur
ons.

2. Asi
ngleact
ionpotenti
alpr
opagat
ingdownamot oraxonresul
tsi
n
Youcor
rectl
yanswered:d.asi
ngl
eactionpot
ent
ial
andasi ngl
econtr
act
il
eev
enti
nthemuscl
efi
ber
siti
nner
vat
es.

3. I
nresti
ngskel
etalmuscl
e,cal
cium i
sst
oredin
Youcorr
ectl
yanswered:
c.thesar
coplasmi
creti
culum.

4. Dur
ingthelatentper
iodforanisometri
ccontr
acti
on
Youcorrect
lyanswered:c.t
hecell
ularev
entsinv
olvedinexci
tat
ion-
cont
ract
ioncoupl
i
ngoccur
.

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04/
21 page1
Experi
ment
Result
sPredi
ct
Questi
on:
Predi
ctQuesti
on:
Ast hest
imulusvol
tagei
si ncr
easedfrom 1.
0vol
tupt
o10v
olt
s,whatwi
l
lhappent
otheamountof
acti
vefor
cegenerat
edwitheachsti
mulus?
Youranswer:a.Theacti
veforcewil
lcont
inuall
yincr
ease.

Stop&ThinkQuest
ions:
Whatdoy ouseei
ntheact i
veforcedispl
aywhenthesti
mulusvol
tageissett
o0.0,andwhydoesthi
sobser
vat
ion
makesense?
Youcorr
ectl
yanswered:a.0.00g;therewasnoacti
vat
ionofskel
etal
musclefi
bersbythi
ssti
mulus.

Whati
sthelowestst
imulusv
oltagethatinducesact
ivef
orcei
ntheskel
etal
muscl
e?Youcorr
ectl
yanswered:b.t
hresholdvolt
age

6.Entert
hethr
eshol
dv ol
tagef
ort
hisexper
imenti
nthef
iel
dbel
owandt
hencl
i
ckSubmi
tDat
ator
ecor
dyouransweri
nthel
ab
repor
t
Youanswered:0.
8volt
s

12.Entert
hemaximal
vol
tagef
ort
hisexper
imenti
nthef
iel
dbel
owandt
hencl
i
ckSubmi
tDat
ator
ecor
dyouransweri
nthel
ab
repor
t.
Youanswer ed:
8.5

v
olt
sEx
per
imentDat
a:

Volt
age Lengt
h Act
iveForce Passi
veFor
ce Tot
alForce
0.
0 75 0.0 0.0 0.0
0.
2 75 0.0 0.0 0.0
0.
8 75 0.02 0.0 0.02
1.
0 75 0.15 0.0 0.15
1.
5 75 0.43 0.0 0.43
2.
0 75 0.66 0.0 0.66
2.
5 75 0.87 0.0 0.87
3.
0 75 1.04 0.0 1.04
3.
5 75 1.19 0.0 1.19
4.
0 75 1.32 0.0 1.32
4.
5 75 1.42 0.0 1.42
5.
0 75 1.51 0.0 1.51
5.
5 75 1.59 0.0 1.59
6.
0 75 1.65 0.0 1.65
6.
5 75 1.70 0.0 1.70
7.
0 75 1.74 0.0 1.74
7.
5 75 1.78 0.0 1.78
8.
0 75 1.81 0.0 1.81
8.
5 75 1.82 0.0 1.82
9.
0 75 1.82 0.0 1.82
9.
5 75 1.82 0.0 1.82
10.0 75 1.82 0.0 1.82

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Post
-l
abQui
zResul
ts
Youscor
ed100%byanswer
ing6outof6quest
ionscor
rect
ly.

1. Mot
orunitr
ecrui
tmentref
ersto
Youcor
rect
lyanswered:
a.anincr
easei
nthenumberofact
ivemuscl
efi
ber
stoi
ncr
easet
hef
orcedev
elopedi
namuscl
e.

2. Act
ivet
ensi
on(orfor
ce)inaskelet
almuscl
efi
berr
esult
sfrom
Youcorr
ect
lyanswer
ed:a.acti
vat
ionofcr
ossbri
dgecycl
i
ngv i
aincr
easedi
ntr
acel
l
ularcal
cium l
evel
s.

3. The i
sthemi
nimal
sti
mul
usneededt
ocauseadepol
ari
zat
ionoft
hemuscl
epl
asmamembr
ane(
sar
col
emma)
.

Youcor
rect
lyanswer
ed:
d.t
hreshol
dvol
tage

4. Bydefi
nit
ion,
the i
stheamountofst
imul
usr
equi
redt
osuccessf
ull
yrecr
uital
lthemuscl
efi
ber
s
i
ntodev
elopi
ngactiv
eforce.
Youcorr
ectl
yanswered:
c.maxi
malvol
tage

5. Whywasamaxi malvolt
ageobservedi
nthisexperi
ment?
Youcorrectl
yanswered:
b.Atthemaximalvolt
age,all
themusclefi
berscont
ainedi
nthi
smuscl
ear
edepol
ari
zedand
they
all
dev el
opacti
veforce(t
hati
s,theywereall
successf
ull
yrecr
uit
ed).

6. Asuff
ici
entl
yst
rongelectr
icalst
imul
usappli
edtoanisol
ated,mountedskel
etalmuscl
einducesthedev el
opment
ofmuscl
eforce,
ormuscletension.Whi
chofthefol
l
owingstat
ement sconcer
ningthi
sobservat
ionis t rue?
Youcorr
ectl
yanswered:
c.Theel ect
ri
calst
imul
usmimicsacetyl
chol
inerel
easeataneuromuscularjunct
ion

11/
04/
21 page12
Rev i
ewSheetResul t
s
1. Descr ibetheeffectofincr
easi ngsti
mulusv ol
tageoni solatedskeletalmuscle.Speci
fi
cal
l
y,whathappenedtothe
muscl eforcegeneratedwithstrongerelect
ricalst
imulati
onsandwhydi dt hi
schangeoccur?Howwelldidtheresul
ts
compar ewi thyourpredi
cti
on?
Youranswer :
Thet otalforceofthemuscl ei
ncr easeswhent hestimulusv olt
agei sincreased.
My predict
ionswer eaccuratei
nt hattheforcewi l
lconti
nuallyincrease,butIwas
wrongi nfail
ingtoreali
zeitwouldonl ybeacer t
ainpoint.Theact i
v eforceplateu'
dat
8.5volts.

2. Howist
hischangeinwhol
e-musclef
orceachi
evedinv
ivo?Your
answer:
Thewhole-muscleforcei
sachievedinvivobecausebecauseaddi
ti
onal
mot
oruni
ts
wereusedasani ncr
easetotheforceproducedbythetotalmuscl
e

3. Whathappenedint hei
sol
atedskeletal
musclewhent hemaxi malv
oltagewas
appli
ed?Youranswer:
The? ber
sintheisol
atedskel
etal
muscl eswer
edepolarized,andanacti
veforcewas
creat
ed.Maximalvol
tagewasappliedwhenalloft
he? bersintheskel
etalmusclepar
ti
cipat
ed

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04/
21 page13

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