Mycoplasma and Ureaplasma#Source : Murray

Rizka A. Maghfirah

1. Which one is not belong to Mycoplasmatales?

Haematobartonella
Eperythrozoon
Aquicella
Mycoplasma
Ureaplasma
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2. Based on the person who isolated it, What is the other name of Mycoplasma
pneumoniae?
Eaton agent
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3. Which disease that is not caused by Mycoplasma pneumoniae?

Bronchopneumonia
Tracheobronchitis
Pneumonia
Arthritis
Hemolytic anemia
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4. Mention 2 diseases that is caused by Mycoplasma genitalium

Nongonococcal urethritis and pelvic inflammatory disease
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5. Mention 2 bacteria that also grouped with Mycoplasma pneumoniae as the causes of
“atypical community-acquired pneumonia”.
Legionella pneumophila
Chlamydophila pneumoniae
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6. What is the component that construct Mycoplasma’s cell membrane?

sterol
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Mycoplasma and Ureaplasma are L forms. (T/F)

(just intermezzo question tho, doesn’t have any point.)
False
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7. Name the cell wall–deficient bacteria group that do not have sterols in their
cell membrane and can form cell walls under the appropriate growth conditions
L forms
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8. Which antibiotic that doesn’t work to treat Mycoplasma infection?

Doxycycline
Imipenem
Azithromycin
Clindamycin
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9. Which antibiotics that Mycoplasma pneumoniae susceptible to?

Penicillin
Carbapenem
Cefaclor
Ciprofloxacin
Vancomycin

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10. Based on the need of oxygen, Mycoplasma hominis is classified into...bacteria.

Obligate aerobe
Facultative anaerobe
Obligate anaerobe
Microaerophilic
Aerotollerant
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11. Where is the location of P1 adhesin receptor?

base of cilia on epithelial surface
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12. What is the receptor of Mycoplasma pneumoniae?

Sialated glycoprotein receptor
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13. Ciliostasis that is caused by Mycoplasma pneumoniae is similar to MoA of what

Gram-Negative rod toxin?
Tracheal cytotoxin
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14. Apart from Mycoplasma pneumoniae, other Gram-negative rod bacteria that can
cause ciliostasis is...
Bordetella pertussis
Legionella pneumophila
Francisella philomiragia
Cardiobacterium hominis
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15. Which one is not the pathogenicity of Mycoplasma pneumoniae?

Causing ciliostasis
Destroy ciliated epithelial cell
Stimulating inflammatory cells to migrate to the site of infection and release
cytokines
Breaks down lipids and lecithin, facilitating tissue destruction
Change expression of surface lipoproteins
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16. Which one is most commonly colonize in female?

Mycoplasma hominis
Mycoplasma genitalium
Ureaplasma urealyticum
Mycoplasma pneumoniae
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17. Which disease/condition that can be caused by Mycoplasma hominis and Ureaplasma
urealyticum?
Nongonococcal urethritis
Pyelonephritis
Postpartum fever
Premature birth
Spontaneous abortion
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18. Which disease/condition that can be caused by Mycoplasma genitalium and

Ureaplasma urealyticum?
Nongonococcal urethritis
Pyelonephritis
Postpartum fever
Premature birth
Spontaneous abortion
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19. Which one is not the disease/condition that is caused by Ureaplasma

urealyticum?
Pyelonephritis
Pelvic inflammatory disease
Spontaneous abortion
Nongonococcal urethritis
Premature birth
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20. Which one is not the disease/condition that is caused by Mycoplasma hominis?
Pyelonephritis
Postpartum fever
Spontaneous abortion
Postabortal infection
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21. Mention 3 neurological complications of Mycoplasma pneumoniae infection.

Paralysis, meningoencephalitis, myelitis
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22. Which one is not secondary complication of Mycoplasma pneumoniae infection?

Myelitis
Pericarditis
Arthritis
Urethritis
Mucocutaneous lesion

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23. To grow Mycoplasma pneumoniae, the media should be added by these components,
except..
Amoxicillin
pH indicator
Glucose
Salt
Sterol
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24. Name the test that is performed by IgM bind to antigens on the surface of human
erythrocytes at 4° C.
Cold agglutinin
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25. What is the most sensitive diagnostic tests to diagnose tracheobronchitis?

Microscopy
Complement fixation
Cold agglutinin
PCR amplification assay
Culture
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26. What is the drug of choice for children with tracheobronchitis that is caused
by Mycoplasma pneumoniae?
Levofloxacin
Doxycycline
Erythromycin
Tetracycline
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27. Mycoplasmatales that is causing spontaneous abortion is resistant to what

antibiotic?
tetracycline
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28. What is the antibiotic to treat postabortal fever?

Erythromycin
Levofloxacin
Azithromycin
Clindamycin
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29. A 23-year-old woman was admitted with typical signs of an acute urinary tract
infection: fever, pain on tapping over both renal areas and in both flanks, urgency
and dysuria. She had a history of renal colic with spontaneous passage of a renal
stone. After 2 days of urine culture in blood agar the appearance like the image
beside showed up. Which statement is true about this scenario?
The patient got pyelonephritis that is caused by Ureplasma urealyticum
The patient should be treated by erythromycin
The causative agent is Mycoplasma hominis, so it shouldn’t be treated with
macrolide
The best antibiotic to treat her is doxycycline
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30. 35 year-old woman was admitted with a burning sensation upon urination. She
also said her vagina often secreted a white discharge. Modified Thayer-Martin
medium cannot be used to culture the speciment, but on contrary the speciment can
be cultured in media that be added by urea and the buffer. What is the statement is
true about this scenario?
The patient got gonococcal urethritis caused by Neisseria gonorrhoeae
The causative agent is Gram-negative bacteria
The patient got nongonococcal urethritis caused by Mycoplasma hominis so she can’t
be treated by erythromycin
The patient got nongonococcal urethritis caused by Ureaplasma urealyticum so she
can’t be treated by erythromycin
The patient got nongonococcal urethritis caused by Ureaplasma urealyticum so she
can’t be treated by tetracycline

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