MYCOPLASMA UREAPLASMA

SONYA ESTI KHOLIFA

1. In which order Mycoplasma and Ureaplasma is?

Mycoplasmatales
Mycoplasmataceae : Eperythrozoon, Haemobartonella, Mycoplasma, and Ureaplasma.
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2. What is the alternative name of Mycoplasma pneumoniae?

Eaton agent (after the investigator who originally isolated it)

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3. Ureaplasma urealyticum is so named because ?

1. It thrives in the upper urinary tract.
2. It requires urea as a growth substrate.
3. It is a frequent cause of symptomatic urinary bladder infections in young women.
4. It causes chronic urinary tract infections in premature babies born to mothers
with ureaplasmas as part of the genital flora
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4. What is the component of Mycoplasma and Ureaplasma cell membrane?

Sterols
They are unique among bacteria because they do not have a cell wall and their cell
membrane contains sterols.
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5. Mention the smallest free-living bacteria ?

Mycoplasma and Ureaplasma

6. What is the most important protein that helps Mycoplasma pneumoniae adhere to
respiratory epithelium?

P1 adhesin
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7. Initiation of infection by M pneumoniae begins with:

1. Elaboration of a polysaccharide capsule that inhibits phagocytosis
2. Secretion of a potent exotoxin
3. Endocytosis by ciliated respiratory epithelial cells
4. Adherence to respiratory epithelial cells mediated by P1 adhesin
5. None of the above
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8. Which of the following is important in the pathogenesis of mycoplasmal

infections?
1. The peptidoglycan in the mycoplasmal cell wall
2. The presence of lacto-N-neotetraose with a terminal galactosamine as the host
cell receptor
3. The structures and the interactive proteins that mediate adhesion to host cells
4. The absence of cilia on the surface of the host cells
5. Growth in an anatomic site where anaerobic organisms thrive
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9. What is the receptor of Mycoplasma pneumoniae on erythrocytes and epithelial
surfaces?
sialated glycoprotein receptors
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10. Which cytokines released by inflammatory cells by Mycoplasma pneumoniae

infection?
tumor necrosis factor-α and interleukin (IL)-1 and later IL-6
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11. What is the important way of Mycoplasma pneumoniae for evading the host immune
response and establishing persistent or chronic infections?
change expression of surface lipoproteins
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12.Where are M. pneumoniae not colonizes ?

1. nose
2. throat
3. trachea
4. lower airways
5. mouth
5.
nose
throat
trachea
lower airways

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13.Disease caused by Mycoplasma pneumoniae is most common in what range of age?

1. 1 - 5 years
2. 5 – 15 years
3. 15 – 20 years
4. 20 – 25 years
2.
Disease is most common in school-age children and young adults (ages 5 to 15
years), although all age groups are susceptible.
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14.How M. hominis, M. genitalium, and Ureaplasma are transmitted?

sexual contact
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15.How M. pneumoniae transmitted ?

spread via large respiratory droplets during coughing
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16. What is the most common pathological findings in patients with Mycoplasma
pneumoniae infections?
tracheobronchitis
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17. Mention the clinical presentations that is caused by Mycoplasma pneumoniae?

Tracheobronchitis, pharyngitis, pneumonia, secondary complications (neurologic,
pericarditis, hemolytic anemia, arthritis, mucocutaneous lesions)
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18. What appearance can seen on chest radiographs of atypical pneumonia patient ?
patchy bronchopneumonia
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19. What is the neurologic abnormality found because of Mycoplasma pneumoniae

infections?

1. Meningoencephalitis
2. Pericarditis
3. Pemolytic anemia
4. Arthritis
5. Mucocutaneous lesions
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20. Which species of mycoplasmas causes pyelonephritis, postpartum fever, and

systemic infections in immunocompromised patients?

1. Mycoplasma fermentans
2. Mycoplasma orale
3. Mycoplasma hominis
4. Mycoplasma pneumoniae
5. Mycoplasma genitalium

3. M. hominis
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21. What species can causes NGU, pyelonephritis, and spontaneous abortion or
premature birth ?

1. Mycoplasma fermentans
2. Mycoplasma genitalium
3. Mycoplasma hominis
4. Mycoplasma pneumoniae
5. U. urealyticum

5. U. urealyticum
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22. Which species of mycoplasmas causes pelvic inflammatory disease and

nongonococcal urethritis?
1. Mycoplasma fermentans
2. Mycoplasma orale
3. Mycoplasma hominis
4. Mycoplasma pneumoniae
5. Mycoplasma genitalium

5. Mycoplasma genitalium
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23. Infection with Mycoplasma genitalium:

1. is not restricted to the genitourinary tract.
2. results in inflammation causing urethritis in males and cervicitis in females.
3. is best treated with a first-generation cephalosporin.
4. is associated only with nongonococcal urethritis in males.
5. is asymptomatic unless a co-infection with Clamydia trachomatis is present.
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24. What is the most sensitive test for the diagnosis of M. pneumoniae infection?

1. Microscopy
2. Cold agglutinin
3. Enzyme immunoassays
4. Complement fixation
5. PCR amplification tests

5. PCR amplification tests

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25. Which of Diagnostic Tests that not useful for Mycoplasma pneumoniae
infections ?

1. Microscopy
2. Cold agglutinin
3. Enzyme immunoassays
4. Complement fixation
5. PCR amplification tests

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26. What is the laboratory test for detecting Mycoplasma pneumoniae which is
indicated by IgM antibodies that bind to antigens on the surface of human
erythrocytes at 40C?

cold agglutinins
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27. Which of the following Mollicutes has the characteristic “fried egg” appearance
on suitable agar media within 5–7 days of incubation?
1. Mycoplasma fermentans
2. Mycoplasma orale
3. Mycoplasma hominis
4. Mycoplasma pneumoniae
5. All of the above
3. Mycoplasma hominis

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28. Which one of the following is not the drug of choice for atypical pneumonia
caused by M. pneumoniae?

1. Erythromycin
2. Tetracyclines
3. Fluoroquinolones
4. Amoxicillin
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29. Which genus of Order Mycoplasmatales is resistant to tetracycline but sensitive

to erithromycin?
Ureaplasma
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30. Each of the following is associated with genital tract infections except:
1. Mycoplasma hominis
2. Neisseria gonorrhoeae
3. Mycoplasma pneumoniae
4. Chlamydia trachomatis
5. Mycoplasma genitalium
3. Mycoplasma pneumoniae

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