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1000 Biochemistry MCQs
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Peptides & Proteins
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Oxidative
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Lipid Biosynthesis &
Related Molecules
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Biochemistry Questions and Answers –
Peptides and Proteins
« Prev Next »
This set of Biochemistry Multiple Choice Questions & Answers (MCQs)
focuses on “Peptides and Proteins”.
1. During the formation of the peptide bond which of the following takes
place?
a) Hydroxyl group is lost from its carboxyl group of one amino acid and a
hydrogen atom is lost from its amino group of another amino acid
b) Hydrogen atom is lost from its carboxyl group of one amino acid and a
hydroxyl group is lost from its amino group of another amino acid Related Topics
c) Hydroxyl group is lost from its carboxyl group of one amino acid and a
Biochemistry MCQ Questions
hydroxyl group is lost from its amino group of another amino acid
d) Hydrogen atom is lost from its carboxyl group of one amino acid and a Organic Chemistry MCQ Questions
hydrogen atom is lost from its amino group of another amino acid
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Unit Processes MCQ Questions
Answer: a
Explanation: The α-amino group of one amino acid acts as a nucleophile
to displace the hydroxyl group of another amino acid forming a peptide
bond.
2. Peptide bond is a _________
a) Covalent bond
b) Ionic bond
c) Metallic bond
d) Hydrogen bond
View Answer
Answer: a
Explanation: Two amino acids are covalently joined through a substituted
amide linkage called a peptide bond.
3. A tripeptide has _________
a) 3 amino acids and 1 peptide bond
b) 3 amino acids and 2 peptide bonds
c) 3 amino acids and 3 peptide bonds
d) 3 amino acids and 4 peptide bonds
View Answer
Answer: b
Explanation: Monopeptide is a peptide containing single amino acid,
dipeptide contains two amino acids joined by one peptide bond and
tripeptide contains three amino acids joined by two peptide bonds.
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4. The factor which does not a!ect pKa value of an amino acid is _________
a) The loss of charge in the α-carboxyl and α-amino groups
b) The interactions with other peptide R groups
c) Other environmental factors
d) Molecular weight
View Answer
Answer: d
Explanation: The loss of charge in the α-carboxyl and α-amino groups, the
interactions with other peptide R groups and other environmental factors
can a!ect the pKa.
5. Which of the following is a 39-residue hormone of the anterior pituitary
gland?
a) Corticotropin
b) Glucagon
c) Insulin
d) Bradykinin
View Answer
Answer: a
Explanation: Corticotropin is a 39-residue hormone of the anterior
pituitary gland that stimulates the adrenal cortex.
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6. The average molecular weight of an amino acid residue in a protein is
about _________
a) 128
b) 118
c) 110
d) 120
View Answer
Answer: c
Explanation: The average molecular weight of an amino acid residue is
nearer to 128. Because a molecule of water is removed to create each
peptide bond, average molecular weight is 128 – 18 = 110.
7. Which of the following is not the classified form of conjugated proteins?
a) Lipoproteins
b) Glycoproteins
c) Metalloproteins
d) Complete proteins
View Answer
Answer: d
Explanation: On the basis of the chemical nature of their prosthetic
groups conjugated proteins are classified into lipoproteins, glycoproteins
and metalloproteins.
8. Which part of the amino acid gives it uniqueness?
a) Amino group
b) Carboxyl group
c) Side chain
d) None of the mentioned
View Answer
Answer: c
Explanation: Di!erent amino acids contain di!erent side chains which
make them unique.
9. Which of the following information is responsible to specify the three-
dimensional shape of a protein?
a) The protein’s peptide bond
b) The protein’s amino acid sequence
c) The protein’s interaction with other polypeptides
d) The protein’s interaction with molecular chaperons
View Answer
Answer: b
Explanation: The amino acid sequence of a protein determines its three-
dimensional shape.
10. Unfolding of a protein can be termed as _________
a) Renaturation
b) Denaturation
c) Oxidation
d) Reduction
View Answer
Answer: b
Explanation: The proteins lose their quaternary, tertiary, secondary
structure and return to its native state by denaturation process.
11. What are the following is not a factor responsible for the denaturation
of proteins?
a) pH change
b) Organic solvents
c) Heat
d) Charge
View Answer
Answer: d
Explanation: pH change, organic solvents and heat are the factors
responsible for the denaturation of proteins.
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To practice all areas of Biochemistry, here is complete set of 1000+ Multiple
Choice Questions and Answers.
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and Answers – Amino Acids Answers – Working with Proteins
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