Connective Tissue

· Basic type of
t issue that provides structural &

metabolic support for other tissues & organs

throughout he
body
Contains vessels & mediate of
·
blood the
exchange
nutrients , metabolites & waste products between

lissues

·
All C T
-
contain isolated cells surrounded by extracellular

material "matrix"

viscosity and strength vary according to the arrangement of their

extracellular matrix fibrousamorphous components

Locations

·
Omnipresent in te
body ; every organ is composed of some C T .

↳ They bind epithelia hissues to the structures of

he body & hold the parenchymal epitulid
calls together to form he
organs

↳ They bind skeltel muscles

togather and attach tur to bones
by tendons or attach boneslobones

by ligaments

↳ They form robust capsules of organs ; liver spleen

↳ They surround the CNS

by a sheath and some exist in a around

Peripheral nerves a gargalia

↳ Other specialized C T -
= bone ;
cartilage ; peripherd blood

Function

↳ Bind tissues & organs of

he
body
↳Provide physical support (dermis) & source of tensile strength

Cligaments & tendons

↳ Metabolic roles ; storge of fats (white adipose) ; regulation of body to

in newborn (brown adipose)

↳ Form major parts of he body's delences against pathogenic organisms

↳ Involved in processes of tissue repair

components

· All C.T consist of cells

;
extracellular libers & amorphous 2 S
.

Types of Cells :
 alls for
1) synthesis & maintenance of extracellular materia

· Fibroblasts , Chondroblasts ,
Osteoblasts , don toblasts

They produce libers & G S .

2) Cells for storage d metabolism of fact

·
Adipocytes
3Cells with defence & immune functions

· Mast alls , macrophages ; mononuclear phagocyte alls ;

Plasma alls ; WB

Cells
Mesenchyme
·
unspecialized&are capable of diffrentiation into all C T .

types
·

Irregular shape with delicate branching cytoplasmic extension

· Oval nuchi

Fibroblasts

· Stellate Shape

·
contain large nucleus with promenant nuclolous

mature Fibroblast or Librocyte :

· smaller than active libroblast

·
long all with thin cytoplasm

Nuckus is elongated in the

direction of Collagen Libers

Thy maintain he
integrity of

tissue
~ supporting
 2) Reticular Fibers

· Consist of collagen fibrils

·
Composed of type III collagen & type IV (4)

·
loosely packed ;
thin fibrils bound togather by small interfibrillar bridges

·
Arranged in a mesh-like pattern or network in loose C . T , around glands , smooth muscle , bone marrow

& lymphoid organs

3) Elastic Fibers

composed of 3 elaunin elastic

·
types Oxytalan , ,

·
Arranged as fibers or discontinous sheets in the extracellular matrix particulary of

skin , &
lung blood vessels

· Thinner than Collagen Libers Ground Substance of C T

.

GS amorphous transperant material that occupies the space

between the
alls& libers Glycoproteins
of different

- types

of the form
·

Highly hydrated ; mixture

glycosaminoglycans in

of hyaluronic acid a proteoglycans

. T Classification
2

J
V
V

General C .
T Special C T
.

Supporting C T
.

1) Loose(areolar) 1) Adipose 1) Cartilage

2) Dense C T
.
2) Reticular 2) Bone

regular 3) Elastic 3) Peripheral blood

Irregular 4) Mucous