• The skeletal system consists of bones along with their associated connective tissue (cartilage, tendons and ligaments). • consists of dynamic, living tissues that are able to grow • A joint or an ariculation - a place where two bones cometogether; some are movable, some have limited movement Functions of the Skeletal System 1. Support 2. Protection 3. Movement 4. Storage 5. Blood cell production Extracellular Matrix • always contain collagen, ground substance and other organic molecules as well as water and minerals. • matrix of tendons and ligaments - large amount of fibers (tough) • cartilage - collagen and proteoglycans • bone - collagen, minerals and calcium, phosphate • minerals in bone - hydroxyapatite(calcium phosphate crystals) General Features of the Bone Categories based on shape: • long - longer than they are wide; upper and lower limbs • Short - wrist and ankle • flat - relatively thin and flattened shapel certain skull bones, ribs, scapulae, sternum • irregular - vertebrae and facial bones Structure of Long Bone • Diaphysis - Central shaft • Epiphysis - two ends of a long bone • Articular Cartilage - covers the ends of the ephiphyses • Epiphyseal plate/Growth Plate - present on growing bone; replace by epiphyseal line • Medullary cavity - filled with marrow; yellow marrow(adipose tissue); red marrow(site of blood formation) • Periosteum - dense connective tissue covering of the bone with layers consisting of blood vessels and nerves • Endosteum - lining of the medullary cavity Histology of Bone • Osteoblasts - bone-forming cells in the periosteum and endosteum for bone repair and remodeling; • osteocytes; osteoclasts • lamellae - extracellular matrix • lacunae - osteocytes • COMPACT BONE - SOLID MATRIX • SPONGY BONE (Cancellous bone) - lacy network of bone with many small, marrow-filled spaces Compact Bone • form most of the long bone • osteons - concentric rings of lamellae surrounding the Haversian canal • Canaliculi - cell processes which connects the osteocytes Spongy Bone • located mainly on the epiphyses of long bones • interior of all other bones • trabeculae - interconnecting plates of bone ; filled with marrow; no blood vessesls Bone Ossification • formation of bone by osteoblasts • fetal bone development : Intramembranous and endochondral ossification Intramembranous ossification - occurs within connective tissue membrane; bones of the skull; ossification centers Endochondral ossification - occurs within the cartilage; bones at the base of the skull and remaining skeletal system; primary ossification center, secondary ossification center Bone Growth • deposition of new bone lamellae onto existing bone or other connective tissue • Appositional growth - Increase in width or diameter ; deposit new bone matrix on the surface of the bone • Endochondral growth - growth in the length of the bone; occurs in the epiphyseal plate Bone Remodeling • removal of existing bone by osteoclasts and the deposition of new bone by osteoblasts • responsible for changes in bone shape, adjustment to stress and calcium regulation in the body fluids. • too much bone deposited - bone thickness increase and might develop an abnormality • too litte bone deposited - osteoporosis Bone Repair Bone and Calcium Homeostasis • calcium homeostatis - critical for normal muscle and nervous system function • when osteoblast and osteoclast activity is balanced, movement of ca into and out of a bone are equal • maintained by 3 hormones: • Parathyroid hormone (PTH) - parathyroid hormone • Vitamin D - skin and diet • Calcitonin - thyroid gland • PTH • Stimulates osteoclasts to break down bone • stimuates kidney to take up calcium from urine and return it to blood • formation of active vitamin D, promotes calcium absorption from small intestine
Calcitonin - Decrease blood calcium levels by inhibiting osteoclast activity
General Considerations of Bone Anatomy • Foramen - a hole in a bone • canal/meatus - tunnel-like passage throught the bone • fossa - depression in a bone • tubercle/tuberosity - lump on a bone • process- projection from a bone • tubercles and processes - site of muscle attachment
• skeletal bones division - axial and appendicular
THE AXIAL SKELETON Skull, vertebral column, and the thoracic cage THE SKULL • Braincase - encloses the cranial cavity; 8 bones that surround and protect the brain; 14 facial bones • Mandible - freely movable joint of the face • three auditory ossicles of the ear The Skull (Lateral View ) • Parietal • Temporal (joined together by squamous suture) • Frontal and coronal (coronal suture) • Coronal and Occipital (Lambdoid suture) • External Auditory Canal • Mastoid Process • Sphenoid bone • Zygomatic Bone (cheekbone) • Maxilla and Mandible The Skull (Frontal View) • Zygomatic bone • maxilla and mandible • Orbits and the nasal cavity • Openings of the ORBIT • -Superior and Inferior orbital fissures (Nerves and Blood Vessels) • -Optic Foramen (Optic Nerve) • -Nasolacrimal canal (Tears) The Skull (Frontal View) • Nasal septum (Vomer - bony part; perpendicular part of the ethmoid) • Lateral walls of the nasal cavity ( Inferior nasal concha - separate bone; middle and superior nasal concha - projections of the ethmoid bone) • Paranasal Sinuses - decrease the weight of the skull and act as resonating chambers during voice production • (Frontal, maxillary, ethmoidal and sphenoical) • Mastoid Air Cells - open into the middle ear ; auditory tube connects the middle ear to the naspharynx Interior of the Cranial Cavity • 3 cranial fossae (anterior, middle and posterior) • several foramina can be seen in the floor of the middle fossa • eg: foramen rotundum and foramen ovale transmits important vessels and nerves of the face; foramen magnum - Spinal Cord Base of Skull Viewed from Below The Hyoid Bone • unpaired, U-shaped Bone • not part of the skull and has no direct bony attachment to the skull • attachment for some tongue muscles, neck muscles Vertebral Column (Back Bone) • central axis of the skeleton, • Five Major functions of the vertebral extending from the base of the column skull to slightly past the end of 1. Supports the weight of the head the pelvis and trunk • 26 individual bones 2. protects the spinal cord • 7 cervical vertebrae, 12 3. allows spinal nerves to exit the thoracic, 5 lumbar, 1 sacral and spinal cord 1 coccyx bone(5 to 3-4 4. Provides a site for muscle individual bones) attachment 5. permits movement of the head and trunk General Plan of the Vertebrae • Each vertebra consists of a body, an arch and various processes • Body - Weight bearing portion • Intervertebral Disks - Separate the vertebral bodies; formed by fibrocartilage • Vertebral Arch surrounds the Vertebral Foramen (vertebral canal) • 2 pedicles • 2 laminae • single spinous process • Intervertebral foramina • Articular Process (Articular Facet) RIB CAGE • Protects the vital organs within thorax and prevents the collapse of the thorax during respiration • Consists of the thoracic vertebrae, ribs and associated cartilages and sternum Ribs and Costal Cartilages • 12 pairs of ribs divided into true and false ribs • TRUE RIBS - 1-7 ; attach directly to thesternum by means of costal cartilages • FALSE RIBS - 8 -12 , dont attach directly to the sternum; thru common cartilages • RIB 11 and 12, floating ribs Sternum (Breastbone) • MANUBRIUM • BODY • XIPHOID PROCESS • Jugular notch - where the sternum articulates with the sternum • sternal Angle - location of the 2nd rib The Appendicular Skeleton Bones of the upper and lower Limbs, girdles Pectoral Girdle (Shoulder Girdle) • 2 scapulae ; 2 clavicle (attach the upper limb to the body) • scapula (shoulder blade) - flat triangular bone with 3 large fossae • glenoid fossa - where head of humerus is connected • spine • acromion process - point of the shoulder • Clavicle (Collarbone) -first bone to begin ossification in the fetus but last to complete • coracoid process - attachment of arm and chest muscles UPPER LIMB (Arm) • Humerus • head - attaches to the scapula • anatomical neck • great tubercle and lesser tubercle • deltoid tuberosity • epicondyles - provide attachment for forearm muscles Upper Limb (Forearm) • RADIUS - lateral side • ULNA - Medial Side • Trochlear notch - elbow joint • Olecranon Process - point of the elbow • coronoid process
• Styloid process • radial tuberosity Upper Limb (Wrist) • Short region between the forearm and the hand
• 8 carpal bones (scaphoid, lunate,
triquetrum, pisiform, trapezium, trapezoid, capitate and hamate) Upper Limb (Hand) • 5 metacarpal bone - bony framework of the hand • 5 digits - the thumb and the finger • finger - phalanges (proximal, middle and distal) Pelvic Girdle • where the lower limb attach to the body • R & L COXAL Bone (Hip bone) - ilium, ischium, and pubis • iliac crest, ant/sup iliac spine • pubic symphysis • acetabulum • obturator foramen • sacrum • Pelvis - includes the pelvic girdle and coccyx LOWER LIMB (THIGH) • region between the hip and the knee • Femur • head (articulates with the acetabulum of the hipbone) • condyles (articulate with the tibia) • neck (between the head and the trochanter) • patella (kneecap - located within the major tendon of the anterior thigh muscles and enables the tendon to bend over the knee Lower Limb (Leg) • region between the knee and the ankle • TIBIA -Larger; major weight- bearing bone of the leg • FIBULA - head is attached to the proximal end of the tibia • Medial malleolus (tibia) • Lateral Malleolus (Fibula) Lower Limb (Ankle and Foot) • The ankle consists of several • Metatarsal bones and phalanges tarsal bones of the foot • TALUS, CALCANEUS, CUBOID, NAVICULAR, CUNEIFORMS(medial, intermediate, lateral) • talus (articulates with the tibia and fibula - ankle joint) • calcaneus (heel) Stick to the plan. You know it’s not gonna be easy. ;-)