Coniin l mt ancaloit loi piperiin.

Cc cy c cn m cha t 1,5 n 2,0%

Piperidinalkaloide, Coniine c hai lp th : ( S ) - (+) - coniine, v ( R ) - (-) coniine,

Cc cy c cn m
Conine l mt cht lng dng du , Conine tan nh trong nc (1 ml trong 100 ml
nc), nhng rt tt trong ethanol v ether . C8H17N

tn khc
( S ) -2-propylpiperidine
khi lng mol

127,23 g mol -1

Tnh trng vt l

nc

t trng

T 0,84-0,85 g cm -3

im nng chy
im si

-2 C

166-166,5 C {( S ) -Coniin}

p sut hi 23 h Pa (61 C)
ha tan
va phi trong nc (1 ml trong 100 ml nc)
ha tan trong ethanol , diethyl ether
ch s khc x

1,4512 (22 C)

N phn ng 2-picoline vi acetaldehyde trong s hin din ca mt c s di

mt nc n 2-Propenylpyridin rng trn mt cht xc tc racemic conine
hydro ha l:

Enantiopure coniine thu c bng cch phn gii chiral - kt tinh phn on
ca epime ca mui thu c vi (+) - tartaric acid .

Hoc

Hoc

Trc conine c s dng nh l hydrobromide hoc hydroclorid l mt

thuc gim au bn ngoi trong liniments.