DNA, RNA and Protein Synthesis Jeopardy Game

EXEMPLAR SCIENCE LESSON PLAN
GRADE LEVEL QUARTER / DOMAIN WEEK & DAY NO. PAGE NO.
GRADE 10 3rd QUARTER/LIVING THINGS WEEK 5 DAY 1 1
AND THEIR ENVIRONMENT
TEACHER HANDOUT 1
(page 1)
JEOPARDY GAME BOARD
Download template@
http://www.magicnet.net/~itms/jeopardy/index.htm
DNA, RNA, DNA Replication Jeopardy Game Sample
REVIEW QUESTIONS (with answers) FOR EACH CATEGORY

DNA
1. What is the genetic material which serves as a blueprint for all of your traits? (DNA)
2. Name the four nitrogen bases found in DNA (Adenine, Thymine, Cytosine and Guanine)
3. Who discovered that Adenine and Thymine, and Guanine and Cytosine occur in equal quantities in
DNA?(Chargaff)
4. What composes a nucleotide in a DNA molecule? (sugar/deoxyribose, phosphate and nitrogenous base)
5. What type of bond holds together the complementary base pairs found in the strands DNA? (Hydrogen bonds)
RNA
1. What sugar is found in RNA? (ribose)
2. Name the four nitrogen bases found in DNA (Adenine, Uracil, Cytosine and Guanine)
3. What nitrogenous base found in RNA that pairs with Adenine? (Uracil)
4. What are the three types of RNA? (mRNA, tRNA, and rRNA)
5. What delivers the genetic code to ribosomes during protein synthesis? (mRNA)
DNA REPLICATION
1. What is the process where DNA makes an exact copy of itself? (DNA Replication)
2. What enzyme unzips DNA strands? ( Helicase)
3. What enzyme proofreads the nitrogen bases added to DNA to make sure that there are no errors before
replication continues? (DNA Polymerase)
4. What is the complimentary DNA strand to the following sequence? 3’ A G C G T T A C 5’ (5’T C G C A A T G 3’)
5. What enzyme connects the new bases to the old bases in the DNA template? (DNA Ligase)
TEACHER HANDOUT 1
page 2
TRANSCRIPTION
1. What nitrogen base is present in RNA, but not in DNA? (Uracil)
2. What is the process of taking information from DNA (genes) and transferring it to mRNA? (Transcription)
3. In which part of the cell does transcription occur ? (nucleus)
4. What is the complementary mRNA strand for the following DNA sequences? 5’ ACCGTAAT 3’ (3’UGGCAUUA5’)
5. What enzyme is involved in the process of making a strand of mRNA from DNA during transcription? (RNA
Polymerase)
TRANSLATION
1. In which part of the cell does translation take place? (cytoplasm)
2. What structure on a tRNA is complementary to a codon on mRNA? (anticodon)
3. What is the three “letter” sequence on mRNA that codes for an amino acid? (codon)
4. What describes how a sequence of nucleotides specifies the amino acid sequence of a protein? (Genetic code)
5. What is a change in the genetic code? (mutation)
INSTRUCTIONS FOR PLAYING JEOPARDY

http://www.iup.edu/teachingexcellence/reflective-practice/past-events/2008-09/sample-games-to-be-used-in-
the-classroom/instructions-for-playing-jeopardy/
1. Play individually or in groups.

2. Pick a category and a point value.
3. Click on the chosen box for the question.
4. Students must give the answer in the form of a question before clicking again. The teacher may want to set a
time limit for answering the question.
5. To see if a student or group is correct, click again for the answer.
6. Click the “Back to Board” button on the slide to return to the main board.
7.If the student or team is correct, they are awarded the point value of the question. (Click the “Score” button
located on the main board to add the point value to the appropriate team score.)
8.Continue until all questions have been answered. The team with the most points wins.
TEACHER HANDOUT 2
CENTRAL DOGMA ANALOGY

Using Figure 2, Match the term with the right picture
https://teacherknowledge.wikispaces.com/DNA+Demonstration+Lesson+Plan
Figure 2
ANSWER KEY
1. DNA – Blueprint of Tinkertoy Structure
2. mRNA – Messenger
3. Ribosome – Toy Factory
4. tRNA – wrench
5. Amino Acids – Tinkertoy Parts
6. Protein – Tinkertoy Ferris Wheel
Alternative image for Central Dogma Analogy

http://ib.bioninja.com.au/_Media/translation-analogy_med.jpeg
TEACHER HANDOUT 3
PICTURE ANALYSIS
https://www.sciencelearn.org.nz/resources/1328-mistakes-in-dna
QUESTIONS: 1. Predict on the effects of UV Photon in the DNA. (major effect is

shown in the images above)
2. Aside from the UV Photon, what other factors may affect or
change the structure of DNA? (DNA fails to copy accurately,
exposure to chemicals or radiation,etc.
STUDENT ACTIVITY SHEET

Mutation
https://www.google.com.ph/search?site=&source=hp&q=Mutation+worksheet+named+MutationTypesDiffintr&oq=Mutation+worksheet+named+MutationTypesDiffintr&gs_l=p
sy-ab.3..33i160k1l2.49979.82816.0.84637.58.57.1.0.0.0.459.8774.0j34j8j3j1.46.0....0...1.1.64.psy-ab..12.40.7640...0j0i131k1j33i22i29i30k1j33i21k1.KKRJdfd7tyI
I. OBJECTIVES:
1. Identify the type of mutation that occurred in the DNA structure.
2. Describe the results of chromosomal aberrations.
II. MATERIALS: Normal DNA , Mutated DNA and Genetic Code Chart
III. PROCEDURES:
In each of the following DNA sequences, you will use the mRNA and amino acid sequences to identify the
mutation that occurred and the effects of each on, if any. Look and analyze carefully! Circle the change in the DNA
sequence and classify each as either Deletion, Insertion, or Substitution and as either frameshift, missense, silent or
nonsense (hint: deletion or insertion will always be frameshift).
III. DATA AND OBSERVATIONS: GROUP 1
Original DNA Sequence: T A C A C C T T G G C G A C G A C T

mRNA Sequence:
Amino Acid Sequence:
Mutated DNA Sequence #1: T A C A T C T T G G C G A C G A C T

What’s the mRNA sequence? (Circle the change)
What will be the amino acid sequence?
Will there likely be effects?
What kind of mutation is this (frameshift, missense, silent, nonsense)?
IV. ANALYSIS:
1. What kind of mutation is more likely to result in a nonfunctional protein?
2. Differentiate frameshift mutation from point mutation.

Mutation
I. OBJECTIVES:
II. MATERIALS:
Normal DNA , Mutated DNA and Genetic Code Chart
III. PROCEDURES:

mRNA Sequence:
Mutated DNA Sequence #2: T A C G A C C T T G G C G A C G A C T

IV. ANALYSIS:
2. Differentiate frameshift mutation from point mutation.

Mutation
I. OBJECTIVES:
II. MATERIALS:
III. PROCEDURES:

mRNA Sequence:
Mutated DNA Sequence #3: T A C A C C T T A G C G A C G A C T

IV. ANALYSIS:
2. Differentiate frameshift mutation from point mutation?

Mutation
I. OBJECTIVES:
II. MATERIALS:
III. PROCEDURES:

mRNA Sequence:
Mutated DNA Sequence #4: T A C A C C T T G G C G A C T A C T

IV. ANALYSIS:

Mutation
I. OBJECTIVES:
II. MATERIALS:
III. PROCEDURES:

mRNA Sequence:
Mutated DNA Sequence #5: T A C A C C T T G G G A C G A C T

What will be the corresponding mRNA sequence?
IV. ANALYSIS:

DNA, RNA and Protein Synthesis Jeopardy Game

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EXEMPLAR SCIENCE LESSON PLAN

DNA, RNA, DNA Replication Jeopardy Game Sample

REVIEW QUESTIONS (with answers) FOR EACH CATEGORY

INSTRUCTIONS FOR PLAYING JEOPARDY

1. Play individually or in groups.

CENTRAL DOGMA ANALOGY

Alternative image for Central Dogma Analogy

QUESTIONS: 1. Predict on the effects of UV Photon in the DNA. (major effect is

STUDENT ACTIVITY SHEET

III. DATA AND OBSERVATIONS: GROUP 1

Original DNA Sequence: T A C A C C T T G G C G A C G A C T

Mutated DNA Sequence #1: T A C A T C T T G G C G A C G A C T

STUDENT ACTIVITY SHEET

III. DATA AND OBSERVATIONS: GROUP 2

Original DNA Sequence: T A C A C C T T G G C G A C G A C T

Mutated DNA Sequence #2: T A C G A C C T T G G C G A C G A C T

STUDENT ACTIVITY SHEET

III. DATA AND OBSERVATIONS: GROUP 3

Mutated DNA Sequence #3: T A C A C C T T A G C G A C G A C T

STUDENT ACTIVITY SHEET

III. DATA AND OBSERVATIONS: GROUP 4

Original DNA Sequence: T A C A C C T T G G C G A C G A C T

Mutated DNA Sequence #4: T A C A C C T T G G C G A C T A C T

STUDENT ACTIVITY SHEET

III. DATA AND OBSERVATIONS: GROUP 5

Mutated DNA Sequence #5: T A C A C C T T G G G A C G A C T

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