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1. Maintain Homeostasis
By controlling the visceral function Somatic Sensory
Sympathetic
Division
2. Coordinate body’s response to stress and
exercise
Example: When you ran 300m, you will Parasympathetic
Division
experience changes or bodily responses
that will adapt for that particular change
like sweating and increase in heart rate CNS – contain cell bodies that process and interpret
etc. all neural information. Located at the central
3. Assist the endocrine system in reproduction neural axis.
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If we are talking about the peripheral nerves, it is
referred as to DRG.
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The Sensory of the PNS has nothing to do with the ANS o From the CNS, there is only one alpha
because what is generated by ANS is a motor output motor neuron.
which will control cardiac and smooth muscle. Autonomic will be utilizing two order neuron:
Preganglionic Neuron & Post Ganglionic Neuron
In Terms of Neurons:
Somatic will only utilize one order neuron
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POSTGANGLIONIC NEURON
Cell body is found outside the CNS (“autonomic
ganglia”)
Axon is unmyelinated
Synapse with effector organ (cardiac/smooth
muscle and glands)
Most numerous in number compared to
preganglionic.
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Divisions of ANS: Sympathetic & Parasympathetic
MUST KNOW HANGGANG MAKAGRADUATE
Similarities:
Preganglionic Neuron
They will both produce Ach as a
o Intermediolateral Horn of Spinal Cord
neurotransmitter.
Marks the origin of the
Both pre-ganglionic neurons are myelinated
preganglionic neuron of the
The cell bodies of the Pre-ganglionic are in the
sympathetic system,
CNS but their ganglions are found in the PNS.
o Thoracic and Lumbar Segments (T1-L2)
They directly synapse with their effector organ,
o White Rami Communicantes
whether a cardiac, smooth muscle or gland.
These were the exact words of Doc JC from the recordings:
Differences: Intermediolateral horn of spinal cord will mark the
The length of the Pre-ganglionic axons of the origin of the preganglionic neuron of the sympathetic
Parasympathetic is longer than the system, that’s the first order neuron and is located at
Sympathetic. T1 – L2 of spinal cord.
The length of the Post-ganglionic axons in the Meaning, the cervical segments should not have
The Post-ganglionic of the Sympathetic will intermediolateral horn even L3 below.
produce Norepinephrine while the Post- This is the reason why we also call the
ganglionic of the Parasympathetic produces sympathetic nervous system as
Acetylcholine Thoracolumbar Outflow because it will
originate from the thoracic and lumbar
Parasympa Sympathetic segments.
thetic Once it exits the spinal cord, it will now form
Length of Longer Shorter the White Rami Communicantes
Preganglionic
Axon
Postganglionic Neuron
Length of Shorter Longer
Postganglionic o Paravertebral Ganglia
Axon o Prevertebral Ganglia
Neurotransmitter Ach Ach o Gray Ramus Communicantes
of Preganglionic
Neurotransmitter Ach Norepinephrine The preganglionic neuron will either synapse to the
of (with exception of paravertebral ganglia and prevertebral ganglia and will
Postganglionic the sweat glands, form the Gray Rami communicantes
blood vessels of
skin and muscle
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fibers will use the White Rami Communicantes in
order to synapse with the postganglion.
So if you destroy the White Rami Communicantes,
the axons of the Pre-ganglionic will be destroyed
too and if you destroy the Gray Rami
Communicantes, you will destroy the Post-
ganglionic axons.
But if you destroy the Spinal Nerve, you will
destroy BOTH the axons of the Pre & Post-
ganglionic neuron.
Remember:
Preganglionic – White
Postganglionic - Gray
Lateral Horn
This is where the preganglionic neuron will
originate.
It will exit via the anterior horn via the Anterior
Nerve Root.
o As it reaches the spinal nerve, it needs to
synapse to the sympathetic ganglion.
o Fibers of the preganglionic will form the
white rami communicantes in order to
synapse with the sympathetic ganglion.
Sympathetic ganglion which will
now be the source of postganglionic
neuron and will now from the gray
rami communicantes and will go
Sympathetic chain – found at the sides of the vertebral
back to the peripheral nerve
bodies.
Notice that there are two structures that
Remember:
will connect the sympathetic chain to the Lateral Horn > Preganglionic > White
peripheral nerve. These are called Spinal Sympathetic Ganglion > Postganglionic > Gray
Nerve:
That’s the posterior nerve root and Fate of the Preganglionic Neuron (MUST KNOW MUST
anterior nerve root. KNOW!!!)
The posterior nerve root has a 1. Synapse with adjacent Paravertebral Ganglion
swelling known as DRG. 2. Synapse with Prevertebral Ganglion
The two (Posterior & Anterior 3. Ascend in Sympathetic Chain and synapse with
Nerve Root) will combine to form a higher Paravertebral Ganglion
the peripheral nerve. 4. Descend in Sympathetic Chain and synapse with
Now at T1 to L2, notice that there are a lower Paravertebral Ganglion
structures that will connect the
sympathetic chain with that of the
peripheral nerve. These are called Rami What’s the difference with paravertebral and
vertebral?
Communicantes
Paravertebral – at the side of the vertebra.
One is gray rami other is white
If we’re going to connect this, we now call
rami.
this the sympathetic chain of ganglions or
sympathetic ganglion chain
Prevertebral – group of ganglions that are
not part of the sympathetic chain.
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Preganglionic Axon forming a synapse with
paravertebral ganglion utilizes the White Rami
Communicantes
o in order to reach the paravertebral
ganglion, they must form the white rami
communicantes
Paravertebral Ganglion forms the following (re-
enters the spinal nerve via Gray Rami
Communicantes – before it can form the structures
below, it needs to form the gray rami
communicantes):
o Sympathetic nerve to the eye and salivary
glands
o Sympathetic Nerves (Cardiac and
Pulmonary Plexus)
o Greater Splanchnic Nerve
o Lesser Splanchnic Nerve
o Lumbar Splanchnic Nerve
o Sacral Splanchnic Nerve
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o Occurs primarily during emotional stress
Brainstem Control
o GI
o Arterial Pressure and heart rate
Control of ANS by Higher Centers o Respiration
Hypothalamic Control
END OF TRANSCRIPTION
o Posterior and Lateral Portion of
References:
Hypothalamus
Doc JC’s Recordings
Control the Sympathetic Division
Pre-lecture handouts
o Pre-optic and Anterior Portion of
Snell’s Clinical Neuroanatomy
Hypothalamus
Past Autonomics Transes (Barney & Friends,
Control Parasympathetic Division
Crammer’s Unite)
Cortical Control
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No need to memorize this table. Just familiarize.
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Past E! d. It contains axons of postganglionic neuron of
sympathetic nervous system
57. Similarity between sympathetic and
parasympathetic nervous system: - White and Gray rami communicantes convey
autonomic signals for the SYMPATHETIC NERVOUS
a. Both preganglionic axons are encased by a myelin SYSTEM
sheath
b. Its preganglionic neurons are located outside the 62. True of gray rami communicantes:
CNS – Sympathetic: Within the CNS; Parasympathetic:
Outside the CNS a. It contains axons of preganglionic neuron of
c. Both postganglionic neurons are cholinergic – sympathetic nervous system
Sympathetic Postganglionic Neurons: Norepinephrine b. It contains axons of postganglionic neuron of
with exception of the sweat glands, blood vessels of parasympathetic nervous system
skin and muscle). Parasympathetic Postganglionic c. It contains axons of preganglionic neuron of
Neurons: Acetylcholine parasympathetic nervous system
d. Both preganglionic axons are long – Shorter in d. It contains axons of postganglionic neuron of
Sympathetic; Longer in Parasympathetic sympathetic nervous system
58. True of preganglionic neurons of parasympathetic - White and Gray rami communicantes convey
nervous system: autonomic signals for the SYMPATHETIC NERVOUS
SYSTEM
a. It is adrenergic, axon is long and encased with
myelin sheath, cell body embedded in the CNS 63. True of prevertebral ganglion:
b. It is cholinergic, axon is short and encased with a. Contains cell bodies of postganglionic neuron of
myelin sheath, cell body is found outside the CNS parasympathetic nervous system - Sympathetic
c. It is cholinergic, axon is long and encased with b. Supply the viscera in the abdominal cavity
myelin and cell body embedded in the CNS c. Neurons in paravertebral synapses with prevertebral
d. It is adrenergic, axon is short and has no myelin ganglia – Refer to page 7 of the transcription
sheath, cell body forms ganglia d. It is part of the sympathetic ganglia – Not part of the
59. Similarity between preganglionic neuron of Sympathetic chain
parasympathetic and sympathetic nervous system 64. Sympathetic nerve to the eye and salivary glands is
a. Both neurons form ganglia carried by what cranial nerve?
b. Both are cholinergic a. CN VII and IX
c. No myelin sheath – Preganglionic: myelinated; b. CN IX
Postganglionic: UNmyelinated c. CN VII, IX, X
d. Both axons are short – Parasympathetic: Longer; d. None of the above - “kala ko ba walang sympathetic
Sympathetic: Shorter nerves sa cranial nerves? Bakit may sympathetic nerve
60. True of postganglionic neuron of sympathetic to the eye and salivary glands? It will not be carried by
nervous system the sympathetic nerves, it will pass the wall of blood
vessels in order to reach the eye.” –Doc JC
a. Cholinergic for blood vessels of skeletal muscles
b. Adrenergic for sweat glands – Cholinergic for sweat 65. Preganglionic neuron of the heart is called:
glands, blood vessels of skeletal muscles and skin A. Otic Ganglion – Postganglionic neuron of the Parotid
c. Cholinergic for cardiac muscles – Norepinephrine for Gland
cardiac muscles b. Celiac Plexus
d. Adrenergic for skin blood vessels - Cholinergic for c. Dorsal Motor – Responsible for the formation of
sweat glands, blood vessels of skeletal muscles and Plexuses:
skin
Cardiac and Pulmonary Plexus –
61. True of white rami communicantes; supplies the heart and lungs
a. It contains axons of preganglionic neuron of Celiac Plexus
sympathetic nervous system
b. It contains axons of postganglionic neuron of
parasympathetic nervous system
c. It contains axons of preganglionic neuron of
d. Ciliary Ganglion – Ciliary muscle
parasympathetic nervous system
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66. Pterygopalatine Ganglion is
–
supplies the heart and lungs
b. S2, S3, S4
c. Otic Ganglion – Supplies the Parotid Gland
d. Celiac Ganglion
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