Gland Hormone Target Cell Functions Pineal Melatonin Brain & Helps regulate daily biological Hypothalamus rhythms; inhibits GnRH production. Hypothalamus GnRH (gonadotropin- Anterior Pituitary Stimulates secretion of FSH & LH releasing hormone) CRH (corticotropin- Stimulates secretion of ACTH releasing hormone) TRH (thyrotropin- Stimulates secretion of TSH releasing hormone) GHRH (growth Stimulates secretion of GH hormone-releasing hormone) Anterior TSH (thyroid- Thyroid Stimulates secretion of thyroid Pituitary stimulating hormone hormone and growth of thyroid ACTH Adrenal Cortex Stimulates secretion of (adrenocorticotropic glucocorticoids and growth of hormone) adrenal cortex FSH (follicle- 1. Ovaries Stimulates secretion of estrogen stimulating hormone) 2. Testes Stimulates sperm production LH (luteinizing 1. Ovaries Stimulates ovulation hormone) 2. Testes Stimulates secretion of testosterone GH (growth hormone) Liver, bone, Stimulates widespread tissue cartilage, mucles, growth adipose tissue Posterior ADH (antidiuretic Kidneys Increases water retention Pituitary hormone) Oxytocin 1. Uterus Stimulates uterine contractions 2. Lactating breasts Stimulates release of milk Thyroid T3 & T4 (thyroid Most tissues Elevates metabolic rate; increases hormone) heart and respiration rates; stimulates appetite Calcitonin Osteoblasts Stimulates bone deposition Parathyroid PTH (parathyroid 1. Osteoclasts Stimulates bone reabsorption to hormone) increase blood calcium levels 2. Kidneys Stimulates reabsorption of calcium by the kidneys to maintain blood calcium levels 3. Small intestine Stimulates calcium absorption Pancreas Insulin Most tissues, liver Stimulates cells to take in glucose to lower blood glucose levels; tells liver to store glucose as glycogen. Glucagon Liver Stimulates glycogen conversion to glucose and then the secretion to raise blood glucose levels. Adrenal Mineralocorticoids Kidneys Promote Na+ and water Cortex (aldosterone) reabsorption; K+ excretion; maintain blood volume and pressure. Glucocorticoids Most tissues Stimulates the breakdown of (cortisol) protein & fat to make glucose; suppress the immune system; reduce inflammation Androgens Most tissues Precursors to testosterone, (dehydroepiandrosterone responsible for male secondary [DHEA]) sex characteristics and for sex drive in both sexes. Adrenal Epinephrine Most tissues Raises metabolic rate; increases Medulla heart & respiration rates; increases blood glucose levels (complements SNS) Ovaries Estrogen Most tissues Stimulates female secondary sex characteristics; regulates menstrual cycle and pregnancy Testes Testosterone Most tissues Stimulates male secondary sex characteristics; sex drive and sperm production Other tissues Prostaglandins Many tissues Have variety of functions, such as relaxing smooth muscle in respiratory airways and blood vessels and causing contraction of smooth muscle in the uterus