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Endocrine gland/ Hormone Target organ or tissue Major function is control of:-
source of hormone
Hypothalamus Numerous releasing factors Pituitary gland Hormones release by pituitary

Anterior pituitary ACTH Adrenal cortex Cortisol secretion

(adenohypophysis) (adrenocorticotrophic
hormone)

FSH Ovaries / testes (tubules) Ovarian follicle growth,


oestrogen secretion /
(follicle stimulating spermatogenesis
hormone)

LH Ovaries / testes (Leydig Ovulation, luteinization of


cells) follicle / testosterone secretion
(luteinizing hormone)

GH All tissues Growth; carbohydrate, protein


and fat metabolism
(growth hormone)

TSH Thyroid gland Thyroxine secretion

(thyroid stimulating
hormone)

Prolactin Mammary gland Milk secretion (stimulates)

Posterior pituitary ADH Kidney tubules Water excretion

(neurohypophysis) (antidiuretic hormone) Smooth muscle in arterioles Blood pressure

Oxytocin Uterine smooth muscle Uterine contractions

Mammary gland Milk �let-down�

Pineal gland Melatonin Various tissues Circadian rhythm;

reproduction

Thyroid Thyroxine (T4) Most tissues Metabolic rate;

Triiodothyronine (T3) growth and development

Calcitonin Bone Plasma calcium and phosphate


(lowers)

Parathyroids PTH Bone, kidneys, intestine Plasma calcium and phosphate


(elevates)
(parathyroid hormone)

Thymus Thymopoetin T-lymphocyte cells in Immune responses


blood
(regresses in
adulthood)

Pancreas Insulin Most tissues, notably Glucose utilization;


muscle and liver
(islet cells) (from beta cells) blood glucose (lowers)

Glucagon Primarily liver Blood glucose (elevates)

(from alpha cells)

Intestinal mucosa Gastrin Stomach Acid secretion

Secretin Pancreas Digestive secretions

Cholecystokinin Gallbladder Release of bile

Somatostatin Intestine Acid and intestinal secretions


(inhibits)

Adrenal medulla Adrenaline All tissues Metabolism; heart rate and


output; response to stress and
Noradrenaline exercise

Adrenal cortex Cortisol All tissues Metabolism; response to stress


and exercise
Corticosterone

Aldosterone Primarily kidneys Sodium, potassium and pH


balance

Kidneys Renin (converted to Blood vessel smooth Blood pressure


Angiotensin-II) muscle
Aldosterone secretion
Adrenal cortex

Ovaries Oestrogens Reproductive organs Reproductive development; also


has effects on oestrus behaviour

Progesterone Uterus Uterine condition

(from corpus luteum)

Uterus Prostaglandin Corpus luteum Breakdown of corpus luteum

(PGF2?) (luteolysis)

Placenta Progesterone and oestrogens Corpus luteum Maintenance of pregnancy

(in pregnant mare) eCG (Equine chorionic Ovaries Maintenance of pregnancy


gonadotrophin, PMSG)

Relaxin Uterus Uterine contraction (inhibits)


Cervix, pelvic ligaments Increase in distensibility

Testes Testosterone Reproductive organs Reproductive development; also


has effects on behaviour

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