Endocrine

source oI
gland Hormonhe Target organ or
ussue
Major function is control
OL-
normone

Hypothalamus Numerous releasing Pituitary gland Hormones release by

Tactors pituitary
Anterior pituitary ACTH Adrenal cortex Cortisol secretion

(adenohypophysis)(adrenocorticotrophic
normone)

FSH Ovaries/testes Ovarian follicle growth,

(tubules)
oestrogen secretion/
follicle
hormone)
stimulating Sperma togenesis

LH Ovulation, luteinization of
Ovaries/testes
(Leydig cells) follicle/ testosterone
(luteinizing hormone) secretion

GH All tissues Growth; carbohydrate,

protein and fat

growth hormone) metabolism

TSH Thyroid gland Thyroxine secretion

(thyroid
hormone)
stimulating

Prolactin Mammary gland Milk secretion (stimula tes)

Posterior pituitary ADH Kidney tubules Water excretion

(neurohypophysis) (antidiuretic hormone) Smooth muscle in Blood pressure

arterioles

Oxytocin Uterine smooth Uterine contractions

muscle
Milk let-down'
Mammary gland
Pineal gland Melatonin Various tissues Circadian rhythm

reproduction

Thyroid Thyroxine (T4) Most tissues Metabolic rate;

Triiodothyronine (T3) growth and development

Calcitonin Bone
Plasma calcium and
phospha te (lowers)

Parathyrods TH Plasma calcium and

Bone, kidneys,
intestine phosphate (elevates)
parathyroid hormone)

Thymus Thymopoetin Tlymphocyte cells in Immume responses

blood
(regresses in
adulthood)

Pancreas Insulin Most tissues, notabiy Glucose utilization;

muscle and liver
(1slet cells) (from beta cells) blood glucose (lowers)

Glucagon Primarily liver Blood glucose (elevates)

fromalpha cells)
Intestinalmucosa Gastrin Stomach Acid secretion

Secretin Pancreas Digestive secretions

Cholecystokinin Gallbladder Release of bile

Soma tostatin Intestine Acid and intestinal

secretions (inhibits)

Adrenal medulla Adrenaline All tissues Metabolism; heart rate

and output; response to
Noradrenaline Sress and exercise

Adrenal cortex Cortisol All tissues Metabolism, response to

stress and exercise
Corticosterone

Aldosterone Primarily kidneys Sodium, potassium and pH |

balance

Kidneys Renin (converted to Blood vessel smooth

muscle
Blood pressure
Angiotensin-)
Aldosterone secretion
Adrenal cortex

Ovaries Oestrogens Reproductive organs Reproductive

development; also has
effects orn oestrus
Dehaviour

Progesterone Uterus Uterine condition

(rom corpus luteum)

Uterus Prosta glandin Corpus luteum Breakdown of corpus

uteum

CPGF2)
Cduteolysis)
Placenta Progesterone and Corpus luteum Maintenance of pregnancy
oestrogens
Cin pregnant mare)
ecG (Equine chorionic Ovaries Maintenance of pregnancy
gonadotrophin, PMSG)

Relaxin Uterus Uterine contraction

(nhibits)

Cervix. pelvic
ligaments Increase in distensibility

Testes Testosterone Reproductive organs Reproductive

development; also has
effects on behaviour