HISTOLOGY OF MUSCLE

LABORATORY ORIENTATION
DG
FUNDAMENTAL TYPES OF TISSUE:

EPITHELIAL TISSUE
CONNECTIVE TISSUE
MUSCULAR TISSUE
NERVOUS TISSUE
FUNDAMENTAL TYPES OF TISSUE:

EPITHELIAL TISSUE
CONNECTIVE TISSUE
MUSCULAR TISSUE
NERVOUS TISSUE
 HISTOLOGY OF THE MUSCLE
SUBTYPE PARENCHYMA SHAPE ARRANGEM NUMBER OF LOCATION
ENT NUCLEUS OF NUCLEUS

SKELETAL
MUSCLE Skeletal

HEART
Cardiac

ILEUM
Smooth
SKELETAL MUSCLE CROSS- SECTION
LOW POWER
MAGNIFICATION

Skeletal Muscle cells (A)

are arranged in
bundles (B).

Perimysium is a
connective tissue
surrounding a BUNDLE
of muscle fibers.
SKELETAL MUSCLE CROSS- SECTION
HIGH POWER MAGNIFICATION

Skeletal muscle cells (A) are

multinucleated are located in the
periphery (B).

Each muscle cell is enveloped by

a loose collagenous tissue known
as ENDOMYSIUM (C).

Take note of the continuous

capillary (D) supplying the
muscle.
SKELETAL MUSCLE LONGITUDINAL SECTION
LOW POWER
MAGNIFICATION
The entire muscle cell is
surrounded by a dense
connective tissue known as
EPIMYSIUM (B).

Skeletal myocytes (A) are

elongated with blunt ends
arranged in bundles and are
covered by PERIMYSIUM (D).
SKELETAL MUSCLE LONGITUDINAL SECTION
HIGH POWER
MAGNIFICATION
Take note of the
Endomysium following:
1. Striations
2. Location of nuclei
3. Number of nucleus
4. ENDOMYSIUM which
is a loose connective
tissue covering the
individual muscle
fibers.
SKELETAL MUSCLE LONGITUDINAL SECTION
 HISTOLOGY OF THE MUSCLE

SUBTYPE PARENCHYMA SHAPE ARRANGEM NUMBER OF LOCATION

ENT NUCLEUS OF NUCLEUS

Skeletal Cylindrical
SKELETAL
Skeletal muscle cell/ /elongated Bundles/ Multi- Peripheral
MUSCLE
Skeletal with Fascicles nucleated
myocyte tapered or
blunt ends

HEART

ILEUM
HEART

Cardiac Tissue
HEART HIGH POWER
MAGNIFICATION
Characteristic feature of
the cardiac muscle are the
presence of (encircled)
INTERCALATED DISCS

Take note of the ffg:

1. Presence of striations
2. Number of nucleus
3. Location of nucleus
4. Shape of parenchyma
 HISTOLOGY OF THE MUSCLE
SUBTYPE PARENCHYMA SHAPE ARRANGEM NUMBER OF LOCATION
ENT NUCLEUS OF
NUCLEUS

SKELETAL
MUSCLE

Cardiac
HEART Cardiac muscle cell/ Cylindrical Bundles Mononucleated Central
Cardiac with OR binucleated
myocyte branching
ends

ILEUM
ILEUM
SCANNER VIEW
LAYERS
1. Mucosa
2. Submucosa
3. Tunica muscularis
4. Tunica adventitia
ILEUM
SCANNER VIEW
LAYERS
1. Mucosa
2. Submucosa
3. Tunica muscularis
4. Tunica adventitia

Note the presence of the

characteristic feature of
this organ (encircled)–
PEYER’S PATCHES
ILEUM
LOW POWER
MAGNIFICATION
TUNICA MUSCULARIS LAYER
Take note of the following:
1. Absence of striations
2. Location of nuclei
3. Number of nucleus
4. Shape of the
parenchyma
ILEUM
HIGH POWER
MAGNIFICATION
Take note of the following:
1. Absence of striations
2. Location of nuclei - central
3. Number of nucleus - mono
4. Shape of the parenchyma -
fusiform or spindle-shaped
 HISTOLOGY OF THE MUSCLE
SUBTYPE PARENCHYMA SHAPE ARRANGEM NUMBER OF LOCATION
ENT NUCLEUS OF NUCLEUS

SKELETAL
MUSCLE

HEART

Smooth
ILEUM Smooth muscle Spindle- Layers/ Mono Central
cell/ shaped Sheets Nucleated
Smooth Fusiform
myocyte
 HISTOLOGY OF THE MUSCLE
SUBTYPE PARENCHYMA SHAPE ARRANGEM NUMBER OF LOCATION
ENT NUCLEUS OF NUCLEUS

Skeletal muscle
SKELETAL Skeletal cell/ Cylindrical Bundles/ Multi- Peripheral
MUSCLE Skeletal /elongated Fascicles nucleated
myocyte with tapered
or blunt ends
Cardiac muscle
HEART Cardiac cell/ Cylindrical Bundles Mononucleated Central
Cardiac with and binucleated
myocyte branching
ends

Smooth muscle
ILEUM Smooth cell/ Spindle- Layers/ Mono Central
Smooth shaped Sheets Nucleated
myocyte Fusiform