SYNAPSES.Electn.

cat
• Chemical

EleÑicebSy-ps
connection
↳ direct cytoplasm's
( passive signal transport )
↳
fast
↳
gretel ( no einen potential needed )
→
hep Junction with channels ( connexion
)
connective the new hens

=→☒←É=
rotating
(
each subunit dimension
↳
of
)
=

pure changes

most
efficiency :

cell smaller
↳ when
post synoptic
- is

↳ smell cell has a

higher input resistance ( Ri)
d
amount of cells that can

the membrane
press

higher potential difference

¥↓R-
=

to
her best
charges ere
V2 At × Ri
a→

Invent
Induce INK RELEASE in @
play sie californica
↳
Strong Enough Stimulus

÷ ::;÷÷T÷_T
→

( therefore simultaneous
)W
response

Therefore to idea ink release

you
meet e stimulus which is
strong
to activate all three
enough heavens

cell
↳ es
if it was a
bigger
end therefore low.t
resislouee-f.TV =
11×12 ;) → I must be

greater !
→
Discharge is
synchronous
MEAL PERK
of
ELECTRICAL SYNAPSE !!
Function electrical
of synapses
in

humour is the SAME

harder to electrical
↳
study synopses
to
since
they are herder

target evil modulate

pharmacologically
 Neuromuscular Junction

↳ no
astrocytes
skeletal Ionotropic Receptors
{ only Cholinergic
↳
Muscles
↳ no
hyperpolarization
d- CU
→
Triggers be END PLATE POTENTIAL

that
↳
If triggers en eet.eu
potential
their muscle potential
↳ Gatto ◦ ◦

End Plate → muscle

fiber in close
proximity
with neuronal bantams

Isolate Elul Plate Potential

reduce ACh
↳
effectivity by
toxins
employment of
like
blocks
CURARE
( when
diaphragm
kik
channels
stops →
)
which 7- ones
produce the Earl Pluto Potential ?

www.sh-entperweobility
↳
study
reversal potentials to

to specific ions

↳ End Photo
permeable to both Nat eel Kt

( reversal potential is zero

)
 I -
V relationship for ACh Ionotropic Channel

Dbs
→ ↳" " ° " " " " ˢᵗʰ

✓
KD simple resistor
!
ureeubrohe
→
→

changing
does cut
potential change
the the
permeability of
grate ( VOLTAGE GATED)
NOT

Myastheuie.hu#
communication
effects synaptic
↳

( neuromuscular functions )
the net
END PUNE Potential
always Noches
-

the threshold to initiate a muscular

action potential
→ Autoimmune → Antibodies develop em

Ach receptor
immune
response efreiwst
( → reduced # rent
surface of invaginations
channels )
containing
-
is smaller pest -

synoptic DV

TREATMENT : •
Immunosuppressive
drugs
• Inhibition of Achesterero
 then muscle www.cotieh ?
to
study nerve - vein

↳ wino electrodes

↳
biomedical approaches
¥¥

www.ewsstiwuloh-elecstthAE
↳ are
patients : Trans

ANODE
cathode shinrulrtes

since it is etlroct.mg
← positive cheeses
+ -s
ehepoleriu.my
Recording is either Meenu peter or
Bipolar
↳
usually BIPOLAR

Uripeherreaehug
↳ the Lehew The electrode
when
signal is

"

fuel half ehepeherizatien

"
→ O since it

cunning eel
Wbf ehgreheiwt.ee leaving

Bnpeherbecerchwyb.tomalleus of
ever'd the electrical

disturbances
" "

→ we
employ differential recording
Two electrodes record the Seine
signal
delay )
→

( withe

↳ since
they are close
Together the

wise
They experience is the Seine

↳ it is possible to remove wt
 Ecitotouy out
Inhibitory Synopses

( antagonist )
↳ e. muscular res
pence agonist end
g.
↳ sells
inhibitory
interview new
urn

GABA : main
inhibitory neurotransmitter

↳ ethernet

↳
benzodiazepine : inti -

anxiety
barbiturates sleep
↳ :
inducing
→
different drugs www.hh-e different
receptors in
different ways
Ionotropic ( WABA
a) → Chi
Beuuochiete GABA to work
→
pines were et on

the channels while barbiturates can

work on Their eiom

metabotropic ( HARA f.) → inhibit

by immersing
kteul.cl aerchctenee
-

eel
decreasing
C. att conductance

A-
equilibrium potential -70 mV =

no
equal to resting membrane "
_
⇐
current potential =D how does Cli e- nhilit the
"

mermen
?
Inhibition
cliche polarization
↳ 7- PSP cell needs to be
when pest synoptic
inhibited with respect to en EPSP