Department of Education

Division of City Schools Manila

MANILA SCIENCE HIGH SCHOOL
Taft Avenue, cor. P. Faura St., Ermita, Manila

1st Quarter Learning Material in Grade 8 Biotechnology

Name:_________________________ Grade 8 Section :__________ Score:_____/45

Date Performed:_____ Date Submitted:__________ Teacher: Mrs.Lourdes M. Montenegro

Worksheet No. 8 - DNA Function

Objective: Discuss how a DNA work.

Big Ideas: 1.DNA is the genetic material, and therefore, its structure and functions
constitute the molecular basis of inheritance.
2.DNA stores information that controls both the development and metabolism
of a cell.

Direction: Fill in the blanks with the correct answer based on the Central Dogma of
Protein Synthesis. According to Chargaff’s rule A is always paired to T and C is always
paired to G following the rule of Complementary Base Pairing.

DNA to DNA will undergo what process 1.____________ to provide the complementary
strand based from the original strand.
From DNA to mRNA it will undergo what process 2.__________.
From mRNA to tRNA what process will it undergo 3.__________.
If you are given this strand give the complementary base pairs. Letters only.
DNA DNA mRNA tRNA
A 1. T 11. UA 21.
T 2. A 12. AU 22.
G 3. C 13. CG 23.
C 4. G 14. GCC 24.
C 5. G 15. GCC 25.
G 6. C 16. 26.
A 7. T 17. AUA 27.
T 8. A 18. 28.
C 9. G 19. 29.
C 10. G 20. 30.

Based on your mRNA strand use the Genetic Code to give the corresponding Amino
Acid
31. Isoleucine
32. 40.
33. Alanine

34. Arginine
35. Arginine 41.
36.

37.
38. 42.
39.
Prepared by: Lourdes M. Montenegro, Master Teacher 1, Manila Science High School
Reference: Biology by Mader p. 117
https://www.youtube.com/watch?v=4gFF1-VHHmk (please watch this video)
Use this Genetic Code to identify the amino acid .For example mRNA strand has UUU
the corresponding amino acid is Phe or Phenyl alanine