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  • Lipids

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    Shiela Mae Liwanag
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    This document provides an overview of a comprehensive lipid classification system that aims to standardize lipid nomenclature. It establishes categories for different classes of lipids including fatty acyls, glycerolipids, glycerophospholipids, sphingolipids, sterol lipids, prenol lipids, saccharolipids, and polyketides. Key aspects of the nomenclature system are discussed such as stereospecific numbering, E/Z designations for double bonds, R/S designations for stereochemistry, and the use of suffixes like "-lyso". The classification aims to provide a single nomenclature scheme and consistent chain-numbering across lipid types.

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    This document provides an overview of a comprehensive lipid classification system that aims to standardize lipid nomenclature. It establishes categories for different classes of lipids including fatty acyls, glycerolipids, glycerophospholipids, sphingolipids, sterol lipids, prenol lipids, saccharolipids, and polyketides. Key aspects of the nomenclature system are discussed such as stereospecific numbering, E/Z designations for double bonds, R/S designations for stereochemistry, and the use of suffixes like "-lyso". The classification aims to provide a single nomenclature scheme and consistent chain-numbering across lipid types.

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    © All Rights Reserved
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    8 views1 page

    Lipids

    Uploaded by

    Shiela Mae Liwanag
    This document provides an overview of a comprehensive lipid classification system that aims to standardize lipid nomenclature. It establishes categories for different classes of lipids including fatty acyls, glycerolipids, glycerophospholipids, sphingolipids, sterol lipids, prenol lipids, saccharolipids, and polyketides. Key aspects of the nomenclature system are discussed such as stereospecific numbering, E/Z designations for double bonds, R/S designations for stereochemistry, and the use of suffixes like "-lyso". The classification aims to provide a single nomenclature scheme and consistent chain-numbering across lipid types.

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    © All Rights Reserved
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    of 1

    THE BIG FAT

    A COMPREHENSIVE
    LIPID CLASSIFICATION

    THE BIG FAT SYSTEM

    WORLD OF LIPIDS
    WORLD OF LIPIDS A NATURALLY-OCCURING BIOLOGICAL COMPOUND
    FATS • WAXES • OILS • PHOSPHOLIPIDS & OTHERS

    Stereospecific Numbering Method (Sₙ) for Categories and its Abbreviation


    NOMENCLATURE

    Glycerolipids and Glycerophospholipids with


    only one glycerol group. E/Z designations to illustrate double bond
    geometry. Fatty Acyls FA
    Spinganine and sphing-4-enine-as core
    structures for spingolipid using D-erythro or R/S designations to illustrate Glycerolipids GL
    2S,3R configuration and 4E geometry, stereochemistries
    respectively. Glycerophospholipids GP
    The use of “-lyso” as synonym to determine the
    Sterols use core names such as cholestane, position that lacks a radyl group in
    androstane, and estrane. glycerolipids and glycerophospholipids. Spingolipids SP

    Adherence to the names for fatty acids and acyl Single nomenclature scheme and consistent
    Sterol Lipids ST
    chains (formyl, acetyl, propionyl, butyryl) . chain-numbering

    Usage of “d” and “t” designations in shorthand Prenol Lipids PR


    Condensed text nomenclature for glycan
    portions of lipids: notation of sphingolipids.
    Sugar residues - standard IUPA abbreviations Saccharolipids SL
    Anomeric carbon locants and stereochemistry
    are included. Polyketides PK

    LIPIDS ARE
    AMPHIPHATIC

    STRUCTURE REPRESENTATIONS
    Water

    Polar Head
    (Hydrophilic)

    Lipid Non polar tails


    Bilayer (Hydrophobic)

    The Structure

    CLASSES AND SUBCLASSES

    MAKE TIME FOR SELF-CARE


    Fatty acyls [FA]
    EXPRESS GRATITUDE
    One of the most
    Lorem ipsum dolor sit amet, consectetur adipiscing elit,
    fundamental sed do eiusmod tempor incididunt ut labore et dolore
    categories of biological
    magna aliqua. Ut enim ad minim veniam, quis nostrud
    SSES

    lipids. exercitation ullamco laboris nisi ut aliquip ex ea


    LA SSES

    Can be considered
    commodo as consequat.
    the most reduced end
    product of the Lorem ipsum dolor sit amet, consectetur adipiscing elit,
    A

    & C L
    polyketide pathway. sed do eiusmod tempor incididunt ut labore etSdolore S U B
    It includes the straight- S ES C
    magna aliqua. Ut enim ad minim veniam, Lquis nostrud
    A & S U B
    chain saturated fatty ES
    C

    exercitation ullamco laboris nisi ut aliquip ex ea S


    acids containing a commodo consequat. S
    A

    terminal carboxylic
    CL

    acid.
    Scan me!

    BIOCHEMISTRY LECTURE GROUP 10


    FAHY, E. , ET. AL (2005). A COMPREHENSIVE CLASSIFICATION SYSTEM FOR LIPIDS. J.LIPID RES.
    46: 839-861. DOI: 10.1194/JLR.E400004-JLR200 05019 MWF 7-8AM REGIE JAPSAY
    S.Y 2022 MIDTERM SHIELA MAE LIWANAG

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