Claret School of Zamboanga City

LEVEL II PAASCU-ACCREDITED
Ruste Drive, San Jose Cawa- Cawa, Zamboanga City
Senior High School
SY 2022-2023

LEARNING ACTIVITY SHEET IN GRADE 12 BIOLOGY 2

Activity No.: 7 (Second Semester)
Activity Title: PROTEIN SYNTHESIS: Transcription and Translation
Learning Target: At the end of the lesson, the students CAN:
1. illustrate the steps in protein synthesis: transcription and translation.
1.1 give the base sequence on the complementary strand of the DNA segment; and
1.2 predict the amino acid sequence of the polypeptide synthesized.

Reference/s: General Biology 2, pp. 263-276

Value/s: Awareness, Respect for life

I. Essential Ideas

Protein synthesis involves two- step process (transcription and translation) of genetic information flow which
varies between prokaryotes and eukaryotes:
a. In prokaryotes:
transcription translation
DNA mRNa protein

b. In eukaryotes:
transcription translation
DNA mRNa protein
nuclear membrane cytoplasm

Transcription is defined as a process where genetic information transferred to mRNA to a RNA

molecule, that is, mRNA.

Translation is defined as a process where genetic information transferred to mRNA from DNA is
translated by another RNA, that is, rRNA into amino acid sequences in polypeptides.

Genetic Codes and the amino acids coded

II. Learning Experiences

A. Clarifying Understanding

Directions:
1. Use the DNA code to create your mRNA CODE.
2. Use the mRNA code to create your tRNA code.
3. Use the mRNA code and the Genetic Code to determine your amino acids.

a. b.