SECTION -A 50 Marks

1. Fill in the blanks 6x1=06

a) In cross matching before blood transfusion ---------------RBC’s are mixed with --------
plasma
b) Example of vesicular transport is ---------------
c) Largest salivary gland is ----------------.
d) Glucose enters in the intestine by ------- transport
e) Maintenance of constant internal environment of the body is -----------------
f) In isometric contraction the length of muscle is --------------

2. Choose the correct options in the following multiple choice questions 4x1=04
A) Conversion of fibrinogen to fibrin is by
a) Prothrombin b)Factor VIII c) thrombin d) kali krein
B) Submucous plexus of GIT
a) Myenteric plexus b) Auerbach’s plexus c) Meissner’s plexus d) Extrinsic plexus
C) Chronaxie is a useful index of
a) Excitability b) contractility c) conductivity d) rhythmicity
D) Parameter NOT involved in acid base balance is
a) PH b) PCO2 c) HCO-3 d) PO2

3. A 32 year old female comes in OPD with chief complaints of severe epigastric pain (worse at
night between meals). She had lost 5 kgs weight in 2 months due to decrease intake caused
by the feeling of bloating, early fullness, she also complaints of nausea and vomiting, she
looked pale and exhausted when entered the OPD. Based on the above scenario answer
the following questions: 3x5=15
a) What is the most likely diagnosis?
b) What is the pathophysiology of disease diagnosed?
c) What could be the management for the diagnosed condition?

4. Write short notes on (Any five) 5x2=10

a) Polycythemia
b) Functions of bile
c) Gastric emptying
d) Neuromuscular junction
e) Sodium potassium pump
f) Erythroblastosis fetalis

5. Explain briefly ( Any three) 3x5=15

a) Hemolytic jaundice
b) Intestinal movements
c) Hemostasis
d) Functions of liver
e) Fatigue
 SECTION B 50 Marks

6. Describe homeostasis and explain both feedback mechanisms with examples 1x20=20

7. What will happen and why ( Any Five) 5x2=10

a) Stored blood is not suitable for transfusing WBC and platelets to the recipient
b) Pack cell volume of venous blood is greater than that of the arterial blood
c) Achlorhydria is associated with iron deficiency anemia
d) To cell volume if Na + K+ pump fails
e) To RBC count at high altitude
f) If total gastrectomy done

8. Explain briefly (Any four): 4x5=20

a) Facilitated diffusion
b) Role of ATP in muscle contraction
c) Myasthenia Gravis
d) Ionic basis of action potential
e) Body fluid composition & distribution