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B) Etiology
Acute uncomplicated UTI:
UTI without underlying disease
Escherichia coli: causes 80% of UTI
Gram(-) enteric bacteria{ klebsiella, proteus}
Gram(+) cocci { streptococcus faecalis, staphylococcus saprophyticus-
infections to young sexually active women}
Complicated UTI
UTI with an underlying structural, medical or neurologic disease
Pseudomonas aeruginosa , enterobacter and serratia
They are isolated inhospital acquired infections and catheter associated
UTI
The predisposing factors of UTI are;
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Aging : as people get older , changes occur in the urinary system that
increase the risk of UTI. Changes like reduced bladder capacity,
weakened muscle bladder and decreased hormonal support. Health
condition such as urinary retention urinary incontinence or presences
of urinary catheters can make them more susceptible. Indivduals with
diabetic mellitus are more prone to UTIS. There is impaired immune
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function as the body becomes weak to fight off infections. Elevated
blood sugar levels can promote bacterias to grow especially high
blood pressure.
In females- shorter urethra- the bacteria have a shorter distance to
travel to reach yhe bladder making them easier for them to infect.
Female have shorter urethra than men.
Sexual intercourse, bacteria from the genital ares can be introduced
3
into the urethra and then travel to bladder
Contacceptives, certain contraceptives like diaphrams or spermicides
can increase the risk of UTIS. It changes the balance in the vagina and
urethra.
Incomplete bladder emptying with age, as women there si decrease in
strength and coordination of the muscles involving the bladder
making the bacteria have and environment where it can multiply and
infect.
In males, prostatic hypertrophy, as men age the prostatic gland can
enlarge and obstruct the normal flow of urin and make it difficult to
completely empty the bladder .
Bacterial prostatitis, prostatitis in an inflammation of the prostatic
gland, it can recruit UTIS
3) Bacteria can enter the UT in 4 routes
1. ascending infection; most common route, bacteria ascend throught
urethra into bladder
2)Haemogenous spread; blood borne spread to kidney, it occurs
3)lymphatogenous spread; for men through rectal and colonic lymphatic
vessels to prostate and bladder. For women, through periuterine
lymphatics to urinary tract
4) direct extraction from other organs- pelivic inflammatory diseases ,
genitourinary tract fistulas
5) the organisms virulence factors:
Escherichia coli; fimbriae, toxic production, production of urease
enzyme , resistance to serum bactericidal activity
The clinical features depending on the sit of infection and age of patients
a) On the site
Urethritis: Discomfort in voiding , dysuria , urgency , frequency
Cystitis ; pelvic discomfort, dysuria, pyuria, abdominal pain
Hemorrhagic cystitis :visible blood in urine, irritating voiding symptoms
Pyelonephritis; invasive nature , fever and chills, WBC casts in urine, back
pain, nausea and vomiting
Also sepsis, septic shock, death
B)ON age:
Babies and infants : Failure to thrive , diarrhea, fever,
Children, adult : dysuria, haematuria, vomiting, acute abdominal pain
Adults: LUTIs- dysuria, haematuria
UUTIs- fever, rigor, symptoms of lower UTIs
Elderly :asymptomatic
4)Upper UTIs
Shock
Death
Sepsis
Recurrent UTI
Pyelonephritis
Kidney damage
5)
Diagnosis Interventions Rational Evaluation
Acute Pain 1. Assess and - Pain assessment - The patient's
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related to document the helps in pain level
inflammation patient's pain determining the should be
and infection of level using a intensity of the decreased or
the urinary tract. pain scale. pain and relieved.
2. Administer evaluating the - The patient
prescribed pain effectiveness of demonstrates
medications as interventions. understanding
ordered by the - Pain medications of pain
provide analgesia
healthcare to relieve management
provider. discomfort. strategies.
3. Apply heat - Heat application - The patient
therapy to the helps to reduce reports relief
lower abdomen pain and muscle from pain and
or perineal area, spasm by improved
as appropriate, promoting comfort.
to alleviate pain vasodilation and
and promote increasing blood
comfort. flow.
4. Encourage the - Increased fluid
patient to drink intake promotes
plenty of fluids urinary flow,
to promote dilutes the urine,
urinary flow and and aids in
help flush out bacterial
bacteria. clearance.
5. Provide a - A comfortable
comfortable and environment can
supportive contribute to the
environment patient's overall
that promotes well-being and
rest and help reduce pain
relaxation. perception.
6. Educate the - Education about
patient about completing the
the importance antibiotic course
of completing promotes
the full course of adherence to
prescribed treatment,
antibiotics to preventing the
ensure effective spread of infection
treatment and and recurrence.
pain relief.