ENDOCYTO

Objectives:
- To be able to fully grasp the meaning
of Endocytosis
- Identify the functions of Endocytosis
- To be able to differentiate the 3 types
of Endocytosis
 What is
Endocytosis?
• Endocytosis is the procedure by which molecules are
actively transported into the cell by being engulfed by
WHAT IS its membrane.
• All cells use endocytosis to transport substances that
ENDOCYTOSIS? cannot passively cross the membrane.
• Endocytosis has been demonstrated to facilitate cell
migration in developing tissues.
• It requires energy in the form of ATP (Adenosine
Triphosphate), which is utilized to transport the
components inside the cell.
 Several Functions
of Endocytosis
• Capturing pathogens or other unknown
• Taking in nutrients for cellular growth,
function and repair substances that may endanger the organism

• Cells must be safely disposed of when they stop

• Cells need materials like
functioning properly to prevent damage to other
proteins and lipids to function. cells. These cells are eliminated through
endocytosis.
 Types of Endocytosis

Pinocytosis
Phagocytosis

Receptor - Mediated
Endocytosis

Phagocytosis
- Also known as "cell eating". The process
through which cells take in big particles or
other cells, such as bacteria and damaged
cells.
ENDOCYTOSIS
Pinocytosis
- Also known as "cell drinking". The cell
absorbs elements from the extracellular fluid
that it requires to operate during pinocytosis.
Water and nutrients are examples of these.
 Receptor - Mediated
Endocytosis
- A type of endocytosis in which cell surface
receptor proteins are employed to engulf a
particular target molecule. The coated pits of
the plasma membrane are where the
receptors, which are transmembrane
proteins, gather.
 Example of
Phagocytosis
Phagocytes include a wide range of white
blood cells, such as mast cells, dendritic
cells, neutrophils, and macrophages.
Because they are responsible for locating
and engulfing germs that are entering the
body, white blood cells are referred to be
"professional" phagocytes
 Example of
Pinocytosis
Extracellular fluid and dissolved solutes
are absorbed by the tiny intestinal cells'
microvilli

These cells have been demonstrated to

continuously absorb fluids through
vesicles that continuously pinch off when
materials are ingested based on
microscopic examinations
 Example of Receptor -
Mediated Endocytosis

The import of iron into a mammalian cell

 Summar
y Types of
Functions of Endocytosis Endocytosis
Endocytosis
• Absorbing nutrients • Phagocytosis - known as
• is a process that cells
for cellular function the "cell eating"
us to engulf • Pinocytosis - known as the
• Eliminating pathogens
extracellular material. "cell drinking"
• Disposing of • Receptor - Mediated
old/damaged cells Endocytosis - receptor
proteins on the cell surface
are used to capture a
specific target molecule
 References
Bailey, Regina. “A Definition of Endocytosis With Steps and Types.” ThoughtCo, 20 June 2019,
https://www.thoughtco.com/what-is-endocytosis-4163670. Accessed 1 September 2022.
BD Editors. “Endocytosis - Definition, Types, Function and Example.” Biology Dictionary, 28 April 2017,
https://biologydictionary.net/endocytosis/. Accessed 31 August 2022.
BD Editors. “Pinocytosis - Definition and Examples.” Biology Dictionary, 26 March 2019,
https://biologydictionary.net/pinocytosis/. Accessed 1 September 2022.
“Bulk transport (article).” Khan Academy, n.d., https://www.khanacademy.org/science/ap-biology/cell-
structure-and-function/membrane-transport/a/bulk-transport. Accessed 31 August 2022.
“11.7: Receptor-mediated Endocytosis.” Biology LibreTexts, 3 January 2021,
https://bio.libretexts.org/Bookshelves/Cell_and_Molecular_Biology/Book%3A_Cells_-
_Molecules_and_Mechanisms_(Wong)/11%3A_Protein_Modification_and_Trafficking/11.07%3A_Receptor-
mediated_Endocytosis. Accessed 1 September 2022.
Gleichmann, Nicole. “Endocytosis and Exocytosis: Differences and Similarities.” Technology Networks, 28
April 2020, https://www.technologynetworks.com/immunology/articles/endocytosis-and-exocytosis-
differences-and-similarities-334059. Accessed 31 August 2022.
Lewis, Warren, and Hayley Anderson. “What is Pinocytosis? - Examples, Vs Phagocytosis, Vs Endocytosis.”
MICROSCOPEMASTER, https://www.microscopemaster.com/pinocytosis.html. Accessed 1 September 2022.
The Organic Chemistry. “Cell Transport - Endocytosis, Exocytosis, Phagocytosis, and Pinocytosis.” YouTube,
20 October 2019, https://youtu.be/jn4MTkqbZjg. Accessed 31 August 2022.
Osmosis. “Endocytosis and exocytosis.” YouTube, 7 March 2022, https://youtu.be/HMbNAKUX3i4. Accessed
31 August 2022.