qu trnh to.

methamphetamine c chun b bi s hydro xc tc ca

ephedrine trong axit axetic, c cha mt lng nh axit pecloric
nh mt kch hot. qu trnh ny i hi phi c 4-5 gi, mc d
mt s ni 6-8 gi, hon tt. methamphetamine cng c
th chun b phn ng gia phenylacetone v methylamine,
sau gim cui cng methamphetamine. Qu trnh ny i
hi 6-8 gi t hon thnh
ti liu:. 95-100% ethanol, bohirua natri, 250 ml knh y trn
bnh, tro ngc ngng, ng cao su, Sudafed vin thuc thng mi
mi, khai thc thy tinh phu, 1 mol sodium hydroxide, natrisunfat
khan, diethyl ether, knh an ton, l chn an ton (plexiglass. .. 1-2
"dy), tp d an ton v gng tay. n cng khuyn khch c mt
m chy ha cht kh bnh c sn tt c cc ln. giy qu mu
xanh v , v
. v mt lt dung dch mui bo ha (1 gram cho mi 23 ml)
tt c cc giai on, thy tinh nn c gi rt kh l thuyt.:bn
s thc hin mt dehydrogenolysis xc tc trn pseudoephedrine,
chuyn i n thnh methylamphetamine (tc , bng, hoc thy
tinh l tn gi thng thng)
cu trc tng hp: th tc ny c chia thnh hai phn;
1) sn xut v thanh lc pseudoephedrine. c s min ph.
2) sn xut v thanh lc c s min ph methylamphetamine.
sn xut v thanh lc c s min ph pseudoepehdrine
phng php: c 10 vin nang Sudafed ngoi, v t cc ht trn
nh thnh mt mn n sch s. cc ht cha pseudoephedrine
hydrochloride v ph v c. bp cc ht cho n khi h c nhiu
hn mt bt rt tt.ti ngh s dng 100 mg vin nang vo thi
im ny. Nng sut cui gn ng s c khong 1 gam sn
phm.
Ni 100 ml nc nhit phng vo knh khai thc, v cn thn
thm tt c cc powdder vo knh. t mt np trn phu, o
ngc, v m kha vi. chc chn rng bn ang mc an ton ca
bn knh vo thi im ny!Lc phu xung quanh gii tn cc ti
liu. S c mt s lng ng k cht bt mu trng khng tan,

ng lin quan, y l ph v c. sau 10 pht lc, nhng mt ly

que vo cht lng v chm vo th trn u ca thanh khuy u
mt mnh giy qu xanh m. cc giy qu nn chuyn sang
mu , ni n c xc ng.iu ny c ngha rng cc gii
php c tnh axit, v mt t l ng k ca hydrochloride
pseudoephedrine c trong thc t ha tan trong nc. nu giy
qu chuyn sang mu , bn c th i vo
bc tip theo. nu khng, lp li, ng bt thm 5 pht cho n khi
qu giy khng chuyn sang mu .
Thm 50 ml ca diethyl ether vo phu tch. phi rt cn thn o
giai on ny .chc chn rng bn ang lm vic trong mt
khuvc thng gi tt v ng lm iu g ngu ngc nh ht
thuc l hoc bn xng ng nhng g s xy ra! te diethyl t dy
c hn so vi dung dch nc v s ni trn mt. thm 10 ml ca
hydroxit 1 mol natri, np phu, nghch v ngay lp tc pht
hnh kha vi trt ra khi kh hnh thc. tr cui phu ra khi
con mt ca bn! nh k xoy v trt phu pht hnh bt k
kh. khi khng kh hn c sinh ra sau khi trt, v ra mt t cht
lng t cc lp thp hn vo mt ci . th nghim n vi mt
ming ca giy qu m. nu n vn , thm 10 ml
natrihydroxit gii php, o ngc phu, xoy v l thng hi cho
n khi khng kh hn c a ra tt.lp li iu ny cho n khi
giy qu mu chuyn thnh mu xanh. giai on ny, cc
dung dch nc l c bn, hydrochloride pseudoephedrine l trong
cc c s min ph hnh thc, v nm hon ton bn trong lp
diethyl ether. gn ly lp nc thp hn v loi b n. ra ether
lp cho vo cc vi 10 gram khan natri sulfat. natri sulfate l mt
tc nhn lm kh v s loi b hu ht cc nc l trong
gii php ether (rt t thc s k t khi ether l khng cc v nc
l rt cc
). np cc vi mt mnh Saran wrap v cho n ngi trong mt
khu vc mt m cng overnite thng gi (khng t lnh). khng
ht thuc l trong vong 2 km ny. ether l d chy v to thnh
peroxit n m c xu hng mt cch t nhin pht n.
gn ra khi ether vo mt bnh y trn kh. nhit bnh ny
trn mt ni nc rt nng. iu ny s ch mt mt vi pht
bay hi. Bn s b b li vi mt cht lng syrupy r rng ging

nh tr em tylenol git. y l c s min ph thun ty

pseudoephedrine.

sn xut ca c s min ph methylamphetamine

thm ethanol 95% hoc everclear tng git cho n khi bn
ha tan. n phi i vo gii php rt d dng. ti nghi ng n nu
nhiu ngi s c th c c 100% ethanol, nhng tinh khit
hn th cng tt, v du vt lng nc hn ch bc tip theo
trong vic chun b. tng khi lng khng c vt qu 50 ml
vo thi im ny. bn c th lm gii php ln n 50 ml nu bn
mun.rt cn thn thm 1 gam natri Bohirua vi cc gii php
thm condensor relux trn cng ca vng bnh y, v bt u
un si hn hp (v d, trn mt tm nng ... khng phi trn mt
ngn la. nc lnh i qua cc tro ngc condensor s gi
ethanol t bc hi, cc ngi
Kt qu (Ting Vit) 2:

C10H15N
qu trnh to
Methamphetamine c iu ch bng hydro ha cht xc tc ca
ephedrin trong axit axetic, c cha mt lng nh cc axit pecloric
l mt activator. Qu trnh ny yu cu t 4 n 5 gi, mc d
mts ni 6-8 gi, hon thnh. Methamphetamine cng c th
iu ch bng phn ng gia phenylacetone v methylamine,
sau gim cui cng methamphetamine. Qu trnh ny yu
cu 6-8 gi t hon thnh.
vt liu: 95-100% ethanol, borohirua natri, 250 ml vng di
knh flask, tro ngc bnh ngng, ng cao su, vin nang
decongestant mi Sudafed, ly khai thc knh, 1 phn t natri
hydroxit, Khan natri sulfat, diethyl te, knh an ton, an ton l
chn (Plexiglas...1-2 "dy), Sn an ton v gng tay. N cng
c khuyn khch c mt m chy kh ha hc
bnh c sn ti mi thi im. Mu xanh v mu Giy qu giy,
v v mt lt dung dch mui bo ha (1 gram mi 23 s mls).
giai on tt c, thy tinh nn c gi rt git.
l thuyt: Bn s thc hin mt xc tc dehydrogenolysis trn
pseudoephedrine, chuyn i n thnh methylamphetamine
cu trc tng hp: th tc ny c chia thnh hai phn;

1) sn xut v thanh lc ca pseudoephedrine min ph base.

2) sn xut v thanh lc ca c s min phmethylamphetamine.

Sn xut v thanh lc ca c s min ph pseudoepehdrine
phng php: tho 10 sudafed vin nang, v t vng ht t
thnh mt mn n sch. Cc ht chaHircloruapseudoephedrine
v v c ph. bp cc ht cho n khi khng c nhiu hn mt
rt tt bt. Ti ngh s dng vin nang 100 miligam ti thi
im ny. Khong cui nng sut s khong 1 gram ca sn phm.
ni 100 s mls nhit phng nc vo knh khai thc, v cn
thn thm tt c powdder vo knh. t mt np trn cc
knh, o ngc, v m kha. M BO RNG BN ANG MC AN
TON CA BN KNH VO THI IM NY! Swirl knh xung quanh
ha tan cc ti liu. C s c mt s lng ng k ca
undissolved bt mu trng; ng c lin quan, iu ny l v c
ph. Sau 10 pht lc, nhng mt ly que vo cht lng v touch th
trn mi ca thanh khuy mt mnh giy giy qu m mu
xanh. Giy giy qu nn bt ni n c xc ng. iu ny
c ngha rng cc gii php c tnh axit, v rng mt ng k t l
Hirclorua pseudoephedrine c trong thc t ha tan trong nc.
Nu giy giy qu bin mu , bn c th i vo bc tip
theo. Nu khng, hy lp li ng lc 5 pht na cho n khi giy
qu giy chuyn sang mu . Thm 50 mls diethyl te tch
knh. HY RT CN THN NY GIAI ON. Lm cho chc chn
rng bn ang lm vic IN A cng thng gi l v xin vui lng
khng lm mt ci g ngu NGC nh khi thuc l hoc bn
xng ng nhng g s xy ra! diethyl te l nh hn cc gii php
nc v s ni trn u trang. thm 10 s mls hydroxit natri phn
t 1, cap cc knh, o ngc v ngay lp tc pht hnh kha
vent ra kh m cc hnh thc. im cc kt thc ca cc knh t i
mt ca bn! Theo nh k xon v vent knh pht hnh bt k
kh. Khi khng kh thm c a ra sau khi venting, v mt
t cht lng t cc lp thp hn vo mt thimble. Kim tra n vi
mt mnh m giy giy qu . Nu n c mu , thm 10
thm s mls ca natri hirxt, o knh, xon v vent cho n khi
khng kh thm c ra. Lp li iu ny cho n khi giy giy qu
mu xanh. giai on ny, cc nc gii php l c bn,
pseudoephedrine Hirclorua l cc c s min ph hnh thnh,
v nm hon ton bn trong lp diethyl te. v ra tng cha nc

thp v loi b n. ra cc te lp vo mt cc vi 10 gram Khan

natri sulfat. Natri sulfat l mt tc nhn lm kh v s loi b hu
ht cc nc l trong cc te gii php (thc s rt t k t khi te
l khng phn cc v nc l rt cc). M cc vi mt mnh bc
saran v cho n ngi trong mt tt thng gi mt tch overnite
(khng t lnh). Khng ht thuc trong vng 2 dm trong y. te
l d chy v hnh thc peroxides n m c xu hng t
phtn. Decant ra cc te vo mt Git vng di bnh. un nng
bnh ny trong mt ni nc rt nng. iu ny s ch mt vi pht
bay hi. Bn s cn li vi mt cht lng r rng syrupy trng
ging nh tr em tylenol git. y l s tinh khitpseudoephedrine
min ph base.
sn xut c s min ph methylamphetamine
Thm 95% ethanol hoc everclear th bng cch th cho n khi
bn l gii tn. N nn i vo gii php rt d dng. Ti nghi ng
n nu nhiu ngi s c th c c 100% ethanol, nhng cc
purer cng tt, k t khi theo di mt lng nc c ch bc tip
theo trong chun b. tng khi lng khng vt qu 50 s mls vo
thi im ny. Bn c th lm cho gii php ln n 50 s mls nu
bn mun. RT cn thn thm 1 gam Natri bohirua gii php,
thm relux condensor n nh ca vng rt flask, v bt u
un si hn hp (v d, trn mt tm nng...Khng phi trn mt
m ngn la. Nc lnh i qua condensor tro ngc s gi cc
ethanol t bc hi, ye

. Tht khng may, c c xu hng l mt tha thun tuyt

vi ca ng truyn thuyt l blatantly sai v
methamphetamine v cc hp cht tng t. Ti liu ny
cng c gng ch ra mt s nhng huyn thoi ph bin
hn, v cung cp gii thch hp l.

methamphetamine:

nhng g chng ti c ngha l bi Hirclorua l rng n

thnh lp mt "mui". Cu trc c bn l khng thay
i, nhng mt phn t HCl tr nn thu ht cc c s
min ph. Trong trng hp ny, hydro t HCl tr
nnthu ht vi nit trong c s min ph. bn s nhn thy
rng cc hnh thc mui l ph bin hn. iu ny l v l
do sinh l. Phn ng tng t m thu ht cc c s min
ph HCl cng c th thu ht n cc phn t khc, gy
kch ng v triu chng khc.
gim vi axit Hydroiodic v pht pho Phng
php 4: gim vi axit Hydroiodic v pht pho
trong th tc ny, nhm ru ca ephedrine
pseudoephedrine hoc PPA l gim bng cch un si mt
trong cc hp cht ny mt hn hp ca hydroiodic pht
pho axit v mu . Hydroiodic acid hot ng nh mt
cht kh bi v ca n dissociates cc nhit cao hn
it v hydro, m thc hin cc vic gim. S phn ly c th
o ngc. Cn bng chuyn trong li ca phn ly bng
cch thm pht pho vo hn hp. Pht pho phn ng
vi it sn xut PI3, sau tip tc phn ng vi nc
hnh thc pht pho acid v acid hydroiodic thm. K t
khi cc nguyn t hydrogen ca HI c hp th bi
ephedrin, pht pho hot ng nh mt ti ch.
Trong mt s ct gim, s cn thit cho HI dispensed vi
ch bng cch trn pht pho v it tinh th trong mt
dung dch nc. Pht pho sau i vo lm cho HI
bi trn cp n qu trnh. Vi mt s lng nh ca
chm sc, iu ny l mt thay th tuyt vi mua, n
cp, hoc lm ca ring bn tinh khit hydroiodic axt.
php ny c li th l d dng lm. N l trc y l
phng php ph bin nht meth t ephedrin. By gi
pht pho l tn California ca t ha cht b gii hn, v
vy mt mc gia tng ca subt

. Hydro ha sn phm ny l d dng: s dng pin lithium

nhm hydride, bohirua natri, hoc thm ch kh hydro vi
niken hoc bch kim kim loi nh mt cht xc tc. Sn
phm ca bc ny l N-methylamphetamine v HCl. Bay
hi ra khi nc v bn c methamphetamine
hydrochloride. Phng php 4: Gim Vi Acid Hydroiodic
v Photpho Trong th tc ny, cc nhm ru ca
ephedrine, pseudoephedrine, hoc PPA c gim bng
cch un si mt trong nhng hp cht trong mt hn hp
ca axit hydroiodic v photpho . Axit Hydroiodic hot
ng nh mt cht kh v phn ly ca n nhit cao
vi iodine v hydro, m khng gim. Cc phn ly c th
o ngc. Cn bng c chuyn ng h phn ly bng
cch thm pht pho vo hn hp. Photpho phn ng
vi i-t sn xut PI3, sau tip tc phn ng vi nc
to thnh axit pht pho v acid hydroiodic hn. K t
khi nguyn t hydro ca HI ang c hp th bi cc
ephedrine, cc hnh vi photpho nh mt ti ch. Trong
mt s ct gim, nhu cu HI c phn phi vi ch bng
cch trn photpho v tinh th it trong dung dch nc.
Photpho sau i vo lm cho HI bi qu trnh nu
trn. Vi mt lng nh chm sc do, y l mt thay th
tuyt vi cho mt trong hai mua, n cp, hoc lm cho axit
tinh khit ca ring bn hydroiodic. Phng php ny c
li th l d dng lm. y l phng php ph bin
nht ca vic meth t ephedrine trc y. Pht pho
by gi nm trong danh sch California t ha cht hn
ch, v vy mc tng ca subt

Methamphetamine l cu trc tng t methcathinone v amphetamine.

Tng hp l tng i n gin, nhng n nhng ri ro vi cc ha cht d

chy, n mn, c bit l dung mi c s dng trong khai thc v tinh ch,
do , sn xut bt hp php thng c pht hin ra chy, n gy ra bi
vic x l khng ng cc dung mi d bay hi, d chy. Su tuyn ng
chnh ca sn xut bt u vi mt trong hai phenyl-2-propanone (P2P) hoc
vi mt trong cc hp cht ng phn pseudoephedrine v ephedrine . [113]

Tng hp t phenyl-2-propanone vmethylamine trong s hin din ca nhm

hn hp[114]
Mt th tc s dng cc amin gin lc ca phenyl-2-propanone
(phenylacetone) vimethylamine, [115] P2P thng thu c t phenylacetic
acid v anhydrit axetic, [114] mc d nhiu phng php khc c xem
xt, [116] v axit phenylacetic c th pht sinh tbenzaldehyde, benzylcyanide,
hoc benzylchloride. [117] Methylamine l rt quan trng tt c cc phng
php nh vy, v c sn xut t nhin liu my bay m hnhnitromethane,
hoc formaldehyde v amoni clorua, hay methyl iodide vi hexamine. [118]iu
ny tng a thch phng php sn xut bi cc bng ng xe gn my
California, [119] cho n khi cc DEA hn ch cc ha cht c thc hin qu
trnh kh khn. Pseudoephedrine, ephedrine, phenylacetone, v acid
phenylacetic DEA danh sch I v anhydride acetic l danh sch II vo danh
sch DEA ha cht cc bin php quy nh v kim sot. Phng php ny c
th lin quan n vic s dng ca clorua thy ngn v cc l pha sau thy
ngn v dn cht thi mi trng. [120] methamphetamine c sn xut bng
phng php ny l racemic, bao gm mt phn ca khng c
tmlevomethamphetamine ng phn. [121]
Con ng Leuckart thay th cng da trn P2P sn xut mt sn phm
racemic, nhng tin thu c qua methylformamide trong axit formic mt
trung gian N-formyl-methamphetamine, l sau decarboxylated vi acid
hydrochloric. [113] [117]
Hai khng thng xuyn s dng cc tuyn ng amin ch suy gim
cng c bo co. "Nitropropene tuyn ng", trong benzaldehyde
c ngng t vi nitroethane sn xut 1-phenyl-2-nitropropene, sau
c gim hydro lin kt i v gim ca ccnhm nitro bng cch s dng
hydro trong mt cht xc tc palladium hoc hydride nhm lithium. "Oxime
tuyn ng" phn ng phenyl-2-propanol vi hydroxylamine sn xut mt
trung gian oxime tng t, cng c hydro ha bng cch s dng hydro
trong mt cht xc tc palladium hoc hydride nhm lithium. [122]
Methamphetamine bt hp php c thng thc hin bi gim

ephedrine, pseudoephedrine, trong sn xut ng phn dmethamphetamine hot ng. T l chuyn i ti a cho ephedrine,
pseudoephedrine l 92%, mc d thng thng, cc phng th nghim bt hp
php methamphetamine chuyn i vi t l 50% n 75%. [123] Hu ht cc
phng php sn xut bt hp php lin quan n proton ca cc nhm
hydroxyl trn phn t ephedrine, pseudoephedrine.

Gim ephedrine s dng hydro iodide trong s hin din ca photpho

Mc d hn h tr li khm ph ca thuc, Nagai tuyn [124] khng tr
nn ph bin gia cc nh sn xut bt hp php cho n khi ca. Nm 1982, v
bao gm 20% sn xut Michigan vo nm 2002 [125] N lin quan n pht
pho v iodide hydro (cn c gi l axit hydroiodic hoc iohydroic axit).
(Iodide hydro c thay th bi it v nc trong "Moscow tuyn ng"
[126]) iodide hydro c s dng lm gim hoc ephedrine,
pseudoephedrine methamphetamine. [120] nng tin thn l nhanh chng
iot ho ca iodide hydro to thnh iodoephedrine. Pht pho gip trong
bc th hai, bi tiu th i-t hnh thnh triioua pht pho (phn hy trong
nc axit pht pho, ti to hydro iodide). Bi v hydro iodide tn ti trong mt
trng thi cn bng ha hc vi i-t v hydro, phn ng pht pho thay i s
cn bng theo hng sn xut hydro khi it c tiu th. [127] c, cc
nhm ti phm c bit n thay th "" pht pho vi mt trong hai
axit hoc pht pho hypophosphorous acid (Hypo tuyn ng"). [126] [128]
[129] y l mt qu trnh nguy hi cho cc nh ha hc nghip d, bi v kh
phosphine, mt sn phm ph t ch sn xut hydro iodide, [130] l cc k
c hi ht. Cc phn ng cng c th to ra c hi, d chy pht pho
trng cht thi. [120] Methamphetamine sn xut theo cch ny thng l hn
95% tinh khit. [131]

Thionyl clorua tng hp

Cc tuyn ng Emde khi nim tng t lin quan n vic gim ca
ephedrine cho chloroephedrine bng cch s dng clorua thionyl (SOCl 2), tip
theo l xc tc hydro. Cc cht xc tc cho phn ng ny l palladium hoc
bch kim. [113] [132] Cc tuyn ng Rosenmund cng s dng kh hydro v

mt cht xc tc palladium c vi bari sulfat (Rosenmund gim), nhng s

dng axit perchloric thay v clorua thionyl. [117]
Gim Birch, cng gi l "phng php ca c Quc x", tr thnh ph
bin trong nhng nm 1990 n cui v bao gm s lng ln sn xut
methamphetamine trong Michigan vo nm 2002. [125] N phn ng
pseudoephedrine vi amoniac lng khan v kim loi kim nhnatri hoc
lithium. Phn ng ny c cho php ng cho n khi bc hi amoniac.
[122] Tuy nhin, gim Birch l nguy him bi v cc kim loi kim v amoniac l
c hai phn ng rt mnh, v nhit ca dung dch amoniac lm cho n d b
si bng n khi cc cht phn ng c thm vo. N c cc phng
php ph bin nht trong cc tiu bang min Trung Ty ca Hoa K v s sn
c sn sng phn bn amoniac lng cc vng canh tc. [120] [133]
Trong nhng nm gn y, n gin ha "Shake'n Nng" mt ni tng
hp tr thnh ph bin hn. Phng php ny l thch hp cho cc l nh
nh vy m hn ch pseudoephedrine l km hiu qu, n s dng cc ha
cht c d dng hn c c (mc d khng t nguy him hn so vi cc
phng php truyn thng), v n l nh vy d dng thc hin rng mt
s ngi nghin thc hin cc loi thuc trong khi li xe [134] N lin quan
n vic t cc vin nn pseudoephedrine nghin thnh mt container
nonpressurized c chaamoni nitrat, nc, v mt k dung mi nh Coleman
nhin liu [135] hoc t bt u t cht lng, dung dch kim v lithium (t
pin lithium) c thm vo. Hydrogen clorua kh c sn xut bi mt phn
ng ca mui vi axit sulfuric sau c s dng phc hi cc tinh th
cho thanh tnh. Container cn phi c "" nh k ngn chn tht bi
di p lc tch ly, nh tip xc ca pin lithium khng kh c th gy ra mt
ngn la n flash, do phn ng b b ri tr thnh mt mi nguy him
nghim trng cho cc nhn vin cu ha. [136] [137] [138] pin lithium c th
phn ng vi nc lm v mt chic container v c kh nng bt u mt
m chy hoc n. [135]
Sn xut methamphetamine trong thi trang ny c th cc k nguy him
v c lin quan n t vong nhiu. [139] Bi v ngi dng thng xuyn thc
hin cc phn ng trong mt chai hai lt t chc cho cc c quan ca h, c
th pht n nu np c ly ra qu sm hay nu n v tnh perforates, th tc
dn n mt s lng ln cc ca bng nng - v d, khong 70 ti Indiana
trong nm 2010 v 2011. Nh 90% cc trng hp Hoa K thiu bo him
sc khe, v chi ph cc trung bnh cho iu tr ca h l $ 130.000 (60% so vi
trung bnh), m l ch mt phn b p bi Medicaid, phng php tng hp
ny c li cho ng ca cc n v bng bnh vin v chi ph cho
ngi np thu ca hng chc hoc hng trm triu la. [140]

Sn xut v phn phi

Bt hp php methamphetamine quy m cng nghip v nh my ha cht

MDMA (Cikande, Indonesia)

1 lb (454g) methamphetamine c tm thy trn mt hnh khch ti sn bay

quc t Los Angeles (LAX)
Cho n u nhng nm 1990, methamphetamine cho th trng M
c thc hin ch yu l trong phng th nghim chy bng cch bun bn
ma ty Mexico v California. Indiana nh nc cnh st tm thy 1.260 phng
th nghim vo nm 2003, so vi 6 nm 1995, mc d iu ny c th l mt
phn kt qu ca cnh st gia tng hot ng. [141] nm 2007, thuc v cc d
liu thu gi trong phng th nghim cho thy rng khong 80% ca
methamphetamine s dng ti Hoa K bt ngun t phng th nghim ln hn
hot ng da trn Mexico on trn c hai bn bin gii v khong 20% n
t phng th nghim c hi nh (STLs) ti Hoa K. [142]
in thoi di ng v nh tr da trn phng th nghim methamphetamine
gy s ch ca c hai phng tin truyn thng nhng tin tc Hoa K v
cnh st. Phng th nghim ny c th gy ra cc v n [143] v chy v tip
xc vi cng chng vi ho cht c hi.Nhng ngi sn xut
methamphetamine thng b tn thng do kh c. Nhiu s cnh st chuyn
lc lng nhim v o to p ng cc trng hp sn xut
methamphetamine. Cc mi e da ma ty quc gia nh gi, nm 2006 sn
xut do S T php, c tm thy "gim trong nc methamphetamine sn
xut trong phng th nghim nh v quy m ln", m cn gim trong sn xut
methamphetamine trong nc c b p bng cch tng sn xut

Mexico." Bo co kt lun rng "methamphetamine c sn khng c kh nng

gim trong ngn hn". [144]
Phng th nghim Methamphetamine c th to ra khi c hi, chng hn
nh kh phosphine, methylamine kh, hi dung mi, acetonehoc chloroform,
hi it, pht pho trng, khan amoniac, hydro clorua / axit lc thy toan, iodide,
lithium v natri hydro kh, ether, hoc methamphetamine hi. [125] Nu thc
hin bi nghip d, sn xut methamphetamine c th cc k nguy him. Nu
qu nng pht pho , bi v thiu thng gi, kh phosphine c th c sn
xut. Kh ny l c c tnh cao, v nu c s lng ln, c kh nng bng n
khi autoignition t diphosphine, c hnh thnh bi pht pho qu nng.
Trong thng 7 nm 2007, cc quan chc Mexico ti cng Lazaro Cardenas
bt gi mt tu ch 19 tn pseudoephedrine, mt nguyn liu cn thit cho
methamphetamine. [145] Cc l hng c ngun gc Hng Kng v i qua
Hoa K ti cng Long Beach trc khi n Mexico.
Cc tp cht v adulterants
Ti Nht Bn, cn ng kinh methamphetamine thng l tinh th mu
trng c tinh khit cao, nhng c cha cc tp cht khc nhau ty theo
phng tin sn xut, v i khi pha trn.
Tp cht chn on l napthalenes 1 - benzyl - methylnaphthalene v 1,3dimethyl-2-phenylnaphthalene, [127] pht sinh trong Nagai v Leuckart cc
tuyn ng, v cis-trans-1,2-dimethyl-3-phenylaziridine, ephedrine, erythro3,4-dimethyl-5-phenyloxazolidine, pht sinh trong Nagai v Emde cc tuyn
ng vng mt trong cc tuyn ng kh amin. [117] tp cht c trng ca
cc tuyn ng Birch bao gm N-methyl-1-(1 - ( 1,4-cyclohexadienyl))-2propanamine. [122] Methamphetamine sn xut bi cc tuyn ng Birch
cha phenyl-2-propanone, tin thn cho cc tuyn ng kh amin, l mt sn
phm suy thoi. [127] Tuy nhin, cc tp cht chn on c th l khng phi
l rt ng tin cy trong thc t, v ni chung l thch hp hn cho cc k
thut php y nh gi mt h s c nhn ln hn ca cc hp cht vi
lng. [113]
Gi mo chung l dimethyl sulfone, mt c s dung mi v m phm m
khng c hiu qu c bit n trn h thng thn kinh; adulterants khc bao
gm dimethylamphetamine HCl, ephedrine HCl, sodium thiosulfate, clorua
natri, bt ngt, v hn hp c ph vi natri benzoat. [126]
Ti Hoa K, bt hp php methamphetamine trong mt lot cc hnh thc
vi mc gi khc nhau rng ri hn thi gian. [146] Thng thng nht, n
c tm thy nh l mt cht rn kt tinh khng mu. Cc tp cht c th dn
n mt mu nu hoc nu. Thuc c hng v y mu sc c cha
methamphetamine v caffeine c bit n nh yaa tru ku (Thi Lan cho
"thuc in").

Mt hnh thc bt tnh ca methamphetamine c bn nh mt crumbly

nu hoc trng, thng c gi l "tay quay b u phng". [147] N c
th c pha long hoc ct thn kinh khng cht nh inositol,
isopropylbenzylamine hoc dimethylsulfone. Mt phng php ph bin l kt
hp methamphetamine vi cc cht kch thch khc, chng hn nh caffeine
hoc cathine, vo mt vin thuc c bit n nh mt "Kamikaze", c th
c bit nguy him do tc dng hip ng ca cc cht kch thch nhiu. N
cng c th c hng v vi ng cao bnh ko, thc ung, hoc hn hp
thc ung che du v ng ca thuc. Mu c th c thm vo cc meth,
nh l trng hp vi Quik meth Strawberry . [148] [149]
Him khi, hn hp phn ng khng tinh khit t ng hydro iodide / pht
pho c s dng m khng sa i thm, thng l bng cch tim, n
c gi l "con b mu" [122] "Meth du" dng ch c s
methamphetamine th c sn xut bi mt s th tc tng hp. Bnh
thng, n c tinh ch tip xc vi clorua hydro, l mt gii php hoc nh
mt loi kh si sc, v khai thc mui kt qu xy ra do lng ma v / hoc
kt tinh li vi ether / acetone. [122]