MCQs

NUCLEIC
ACIDS

DR. RUCHIKA YADU

Q1. Building blocks of nucleic acids
are

a) Nucleotides
b) Nucleosides
c) Amino acids
d) Histones
Q2. The sugar molecule in a nucleotide is

a) Pentose
b) Hexose
c) Tetrose
d) Triose
 Q3. Group of adjacent nucleotides are
joined by

a) Phosphodiester bond
b) Peptide bond
c) Ionic bond
d) Covalent bond
Q4. What is the composition of
nucleoside?
a) a sugar + a phosphate
b) a base + a sugar
c) a base + a phosphate
d) a base + a sugar + phosphate
Q5. What is the composition of
nucleotide?

a) a sugar + a phosphate
b) a base + a sugar
c) a base + a phosphate
d) a base + a sugar + phosphate
Q6. Which of the following are
not the components of RNA?

a) Thymine
b) Adenine
c) Guanine
d) Cytosine
Q7. Identify the purine base of
nucleic acids in the following

a) Cytosine
b) Thymine
c) Uracil
d) Adenine
Q8. Which of the following is true
about phosphodiester linkage?

a) 5’-phosphate group of one nucleotide unit is joined

to the 3’-hydroxyl group of the next nucleotide
b) 3’-phosphate group of one nucleotide unit is joined
to the 5’-hydroxyl group of the next nucleotide
c) 5’-phosphate group of one nucleotide unit is joined
to the 5’-hydroxyl group of the next nucleotide
d) 3’-phosphate group of one nucleotide unit is joined
to the 3’-hydroxyl group of the next nucleotide
Q9. Which of the following statements
is NOT true?
a) Sugar component of a nucleotide is ribose
b) Sugar component of a nucleotide is
deoxyribose
c) The bases in nucleotides are attached to a
pentose sugar moiety by a glycosidic linkage
d) The sugar molecule of the nucleotide is in L-
configuration
Q10. The sugar in RNA is __________ ,
the sugar in DNA is __________

a) deoxyribose, ribose
b) ribose, deoxyribose
c) ribose, phosphate
d) ribose, uracil
Q11.A five carbon sugar lacking an oxygen
hydrogen at the number 2 carbon is found
in
a) DNA
b) RNA
c) mRNA
d) rDNA
Q12. Which of the following is found
on RNA but not DNA?

a) Uracil
b) Deoxyribose
c) Phosphate
d) Adenine
Q13. Which of the following is NOT
a feature of DNA

a) Base pairs joined by hydrogen bonds

b) Base unit is the nucleoside
c) Strands are complementary and
antiparallel
d) Sugar phosphate backbone
Q14. To which of the following does
thymine form hydrogen bonds in DNA?

a) adenine
b) thymine
c) cytosine
d) guanine
Q15. On which of the following
molecules would you find a codon?

a) messenger RNA
b) ribosomal RNA
c) transfer RNA
d) DNA
Q16. The two strands in DNA
double helix are joined by

a) Covalent bond
b) Hydrogen bond
c) Ionic bond
d) Phosphodiester bond
Q17. Chromatin is composed of

a) Nucleic acids and proteins

b) Nucleic acids only
c) Proteins only
d) None of the above
Q18. A short length of DNA has 80 thymine
and 80 guanine residues. The total no. of
nucleotides in DNA fragment is

a) 160
b) 40
c) 320
d) 640
Q19. DNA is present in

a) Nucleus only
b) Nucleus, Mitochondria and ER
c) Nucleus, Mitochondria and Chloroplast
d) Nucleus, Mitochondria and Golgi Bodies
Q20. The length of one turn of
DNA is

a) 3.4 Å
b) 34 Å
c) 20 Å
d) 3.04 Å
Q21. The width of DNA is

a) 15 Å
b) 3.4 Å
c) 20 Å
d) 34 Å
Q22. DNA is the genetic material
in

a) Some Viruses, prokaryotes and Eukaryotes

b) prokaryotes and Eukaryotes
c) In Eukaryotes only
d) Viruses, prokaryotes and Eukaryotes
Q23. RNA is the genetic material
in

a) Some viruses and prokaryotes

b) Some viruses only
c) Some prokaryotes only
d) Some Eukaryotes
Q24. The pentoses in nucleotides
are

a) In β furanose form
b) In α furanose form
c) Both
d) None
Q25. On which of the following
molecules would you find a anticodon?

a) messenger RNA
b) ribosomal RNA
c) transfer RNA
d) DNA
Ques. Option Answer
1 a Nucleotides
2 a Pentose
3 a Phosphodiester
4 b a base + a sugar 16 b Hydrogen bond
5 d a base + a sugar + phosphate 17 a Nucleic acids and proteins
6 a Thymine
18 c 320
7 d Adenine
19 c Nucleus, Mitochondria and
8 a 5’-phosphate group of one nucleotide Chloroplast
unit is joined to the 3’-hydroxyl group of 20 b 34 Å
the next nucleotide 21 c 20 Å
9 c The bases in nucleotides are attached to
22 a Some Viruses, prokaryotes and
a pentose sugar moiety by a glycosidic
Eukaryotes
linkage
23 b Some viruses only
10 b ribose, deoxyribose
24 a In β furanose form
11 a DNA 25 c transfer RNA
12 a Uracil
13 b Base unit is the nucleoside
14 a adenine
15 a messenger RNA