PARASITIC PROTOZOA (50 Q)#Manson 1238-1249

By: Ge_Awaeh

Outline
Malaria
Babesiosis
Toxoplasmosis
Sarcocystosis
Human African Trypanosomiasis (HAT)
American Trypanosomiasis : Chagas disease
Leishmaniasis
Intestinal protozoa
Pathogenic and opportunistic free living Amebae: Agents of Human and Animal disease
Trichomonas vaginalis

1. Which is the phylum which plasmodium parasite belongs to?

Sporozoa / Apicomplexa
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2. Clinical characteristics:#-incubation period : 8-17 days#-initial fever :

irregular#-periodicity : 48 hours#-illness : benign tertian malaria#-anemia : mild
to moderete#What plasmodium species have these clinical characteristics?#1. P.
vivax#2. P. ovale#3. P. malariae#4. P. falciparum##
P.vivax

Ilness
P. Ovale = Ovale tertian malaria
P. Malariae = Quartan malaria
P. Falciparum = Malignant tertian malaria
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3. Clinical characteristics:#-incubation period : 18-40 days#-initial fever :

irregular#-periodicity : 48 hours#-illness : ovale tertian malaria#-anemia :
mild#What plasmodium species have these clinical characteristics?#1. P. vivax#2. P.
ovale#3. P. malariae#4. P. falciparum##
2. P. Ovale

Ilness
P. vivax = Benign tertian malaria
P. Malariae = Quartan malaria
P. Falciparum = Malignant tertian malaria

4. Clinical characteristics:#-incubation period : 8-11 days#-initial fever :

continuous#-periodicity : 36-48 hours#-illness : malignant tertian malaria#-
anemia : severe#What plasmodium species have these clinical characteristics?#1. P.
vivax#2. P. ovale#3. P. malariae#4. P. falciparum##
4. P.falciparum

Ilness
P. vivax = Benign tertian malaria
P. Malariae = Quartan malaria
P. ovale = ovale tertian malaria

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5. Not true about P. Malariae?##1. Ziemann’s dots#2. Trophozoite : compact, rounded
often band-like#3. Gametocyte apperance in 3 days (early)#4. Merozoites 6-12#
FALSE = 3 ( P.vivax)

TRUE = Gametocyte appearance in several weeks#

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6. True about P. falciparum?##1. Geographic distribution in West Africa and South

Asia#2. Trophozoite : compact, rarely seen in peripheral blood#3. Gametocyte
apperance in 3 days (early)#4. Merozoites 6-12#
TRUE= 2

P. Ovale
P. P.vivax
P. Malariae
#
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7. In the picture above shows Plasmodium falciparum. What stain and shape called ?
Giemsa stain and Crescentic or BANANA shaped or Laveran’s bib
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8. What is the part that serves as petals to the rosette of a schizont of a

plasmodium parasite?
Merozoite
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9. What type of RBC is infected by Plasmodium ovale?

Young, immature RBC

P. falciparum = all RBC

P. vivax and P.ovale = young, immature RBC
P. malariae = mature and berumur
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10. What is the other name for Plasmodium knowlesi malaria?

SIMIAN MALARIA
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11. Which plasmodium species expresses dormancy inside human liver?

P.vivax, P.ovale
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12. What plasmodium species and phase?

P. malariae; Schizont containing merozoites (6-12) giving a coarse granular
appearance
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13. Amongst the plasmodium parasite, one is known to cause pernicious malaria,
which one is it?
P. falciparum
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14. Babesia are tick-borne intraerythrocytic apicomplexan parasites. Mention 3

name of Babesia species!
Babesia microti (US)
Babesia duncani (US)
Babesia divergens (Europe)
Babesia venatorum (europe)
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15. What are natural reservoir host for Babesia sp.?

Field mice, voles, other small rodents
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16. What is infective form of Babesia sp.?

Pyriform body
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17. Examination of blood smear is diagnostic method of choice for babesiosis.

Serologic test and PCR also can used to diagnosis babesiosis. What is diagnostic
stage that become pathognomic for B.microti dan B. duncani called?
Tetrad forms / Multiple small ring forms / Maltese Cross
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18. Toxoplasma gondii is an Apicomplexan parasite with members of the cat family
as .......
The definitive host
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19. Human cells serves as possible nurturing cells of toxoplasma, in life cycle of
Toxoplasma gondii, human serve as?
Accidental Intermediate Host
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20. Toxoplasma is an intracellular obligate parasite mainly infect what cell?

Reticuloendothelial cells
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21. What is the name of test indicated to detect IgG presence in people with
Toxoplasmosis?
The Sabin-Feldman Dye Test
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22. What stage and species?

Cysts, Toxoplasma gondii
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23. Sarcocystis hominis and S.suihominis are related to Toxoplasma, and employ
human as........................ to cause asymptomatic infections or mild to
moderete, self-limiting diarrhoea.
Definitive hosts
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24. Infective stage and diagnostic stage from Sarcocystis spp.?

IS and DS = SPOROCYST
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25. Trypanosoma brucei is transmitted by tsetse fly (Glossina spp.) and there are
3 subspecies are described. Which one is not true?#1. T. brucei gambiense#2. T.
brucei rhodensiense#3. T. brucei cruzi#4. T. brucei brucei#
T. brucei cruzi
T. brucei gambiense & T. brucei rhodensiense affects human
T. brucei brucei affects cattle
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26. T. brucei brucei are susceptible to trypanolytic activity

of ............................ In human sera.
Apolipoprotein L-1 ( APOL1)
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27. Which of the following bug serve as vector of Trypanosoma brucei?

1
2
3
4
Human African Trypanosomiasis (HAT) / Sleeping sickness --Tsetse fly (Glossina
spp.)

2. River blindness ( Onchocerca volvulus) – Blackfly (Simulium damnosum)

3. Loiasis (Loa loa) -- Deer fly / Mango fly
4. Leishmaniasis (Leishmania spp.) – Sand fly ( Phlebotomus spp.)
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28. Megacolon and cardiomegaly both are complications by which Trypanosoma species?
Trypanosoma cruzi
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29. This species may cause what disease beside Trypanosomiasis?

American Trypanosomiasis : Chagas disease, Trypomastigote T.cruzi
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30. Vector of? What is the name of this species?

Trypanosoma cruzi, Reduviid Kissing Bug (Triatoma infestans)
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31. What is the infective form of Leishmania?

Promastigote
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32. What skin test is used to detect Leishmaniasis?

Montenegro Skin Test
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33. What form of Leishmania is almost impossible to be found inside human cells
infected with Leishmania?
Promastigote
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34. Which species is not include in Old World Leishmaniasis?#1. L. donovani#2. L.

infantum#3. L. major#4. L. tropica#5. L. mexicana
5. L. mexicana
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35. Kala-azar is specific lesions that caused by?#1. L. donovani#2. L. infantum#3.

L. major#4. L. tropica#5. L. mexicana
1. L. donovani
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36. There are several genera of Free-Living Amoebae that associated with disease in
human. Which one is not correct below?#1. Naegleria#2. Acanthamoeba#3. Sappinia#4.
Balamuthia#5. Sarcocystis
5. Sarcocytis
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37. What is EA of Granulomatous Amebic Encephalitis?#1. Acanthamoeba castellanii#2.

Sarcocystis hominis#3. Naegleria fowleri#4. Paravahlkampfia francinae
Acanthamoeba castellanii

Selain itu bisa juga Balamuthia mandrillaris

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38. What is EA of non fatal Primary Amebic Meningoencephalitis (PAM)?#1.

Acanthamoeba castellanii#2. Balamuthia mandrillaris#3. Naegleria fowleri#4.
Paravahlkampfia francinae
4. Paravahlkampfia francinae
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39. Which statement is not true about Naegleria fowleri?#1. Stage in human tissue :
trophozoite#2. Habitat : Fresh water#3. Risk in children and young adults#4. Route
of entry: enter through abrassions
4. Route of entry: enter through abrassions (enter through olfactory)

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40. Which statement is not true about Balamuthia mandrillaris?#1. Stage in human
tissue : trophozoite and cyst#2. Habitat : Soil#3. Treatment with Clarithromycin#4.
Route of entry: enter through fecal-oral
4.Route of entry: enter through fecal-oral (abrassions)
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41. Which one is not include in Intestinal protozoa below?#1. E. histolytica#2.

G.lamblia#3. B. coli#4. S. pedata#
4. S. Pedata (free-living amoeba)
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42. Which one is not only have 2 development stages in intestinal protozoa species?
#1. E. histolytica#2. G.lamblia#3. B. Coli#4. C. parvum#5. D.fragilis#
4. Cryptosporidium parvum (oocyst---sporozoite---trophozoite---merozoite---
gametocyte)#
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43.Species and stage?

Entamoeba histolytica , trophozoite
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44.Species and stage

Balantidium coli , trophozoite
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45.Species and stage ?

Giardia duodenalis, trophozoite
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46. Stage?
Oocysts Cryptosporidium spp.
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47. Stage?
Oocysts Isospora belli
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48. Species and Stage?

49. Species and stage?

B.coli, cysts
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50. Which is the only urogenital protozoan parasite in humans?#1. E. histolytica#2.

G.lamblia#3. T. vaginalis#4. C. parvum#5. D.fragilis##
3. Trichomonas vaginalis
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