CCELEBRO

DATE
PAGE
Typhoid Fever

Salmonela Typh ty ph1

. al mon ella
Caustive
Bactem
S pura hy ph

Causesthe enBtt FeNo

AB C

Pathagenes is

Contaminted Ho Xfovc
oa
O Route
Shijellu
o3-108 baullf higher hen
Infechvedose OF
solmonelle
Wpylo inFech'om
RSK Ra chos OAidiy
of inteHnw
O 18D GIT SUsgusy , suppsesjon
Aloa

ucouia
Entay Of epithiatiad Lining of {inteHnaJ
CM) cell
Sal monelle can H9gess +he,
Foomaton oh membsone Ru les on
cell membrane oF M-reU

Backo entlo ted tnto lage vesiCles

The pocess of Uptake Baltema medu'ako

endocytofS
edialed by Speciliged type -secehon SyJeT

Baullr Remain thR Vocu)e i the ydoplou

 to maco phace
Salmolle conkaini e
Mucoia and VacoLule Craoss
Reaah into he he
uo muraic
phyogocL jes bH Hhe
GuaViva ofinside the
Suoviva
rmacrophaaeJ
Mapphacj es S:p in duce
indlu ce Cesten
cesetn
u]4e
on ts Uesnahon
susfaco CLps) So hal
So NO (ongea Suscephble o te
Soomal eny e. ef
ManophaneA -
Spaea:1 8ochemmic - S: insde ihe mauopha
keg
9mphahes
3lood Stoeua taasienr
Baceomiq )
Spoeac bacil diseminted 4rerouth e RE sysem
iver Spleen Cumph lode
and Bone MawdCD)

Othex orgor hden % Ld

tiplicahon fae Plo ce

20 Ba Cheormd
20 Seed OTGWN
cUhich leads to
On set of clinical We ode
 CCELEBRO
DATE

Clinical Man rehon

O Feve
Headoche chills , (ough SweRng
Rasbesh aunk ches
5aoly iheunal monifeashon
GET Bleeting ineai na poskostio )
Aleoplogica maoi Prelh'on.

LABORATORY DI9on*STS
L Impootance of Diagonisi s TO reo pes"E moinkong hespy Sseen în

EHotdyical Agent sTuphi , panty ph

S n SPeumen (ollecno )
T T3anspo8
M MoCosopiC Apooch
MiDscoptc Aorch Grarm -ve Soaun
C Coltume
B ischemical Reah
A AoHbiotic, sug4bil} TES
Sembiogf cod Method
A
AnHgen Dekechon Tej - by ELTSA
M Moleculan Test,
A Animal mcolum
pCR delech na (Falgeuind gene,
ro B
amd FC gene
Specimen collechon 0Blood

Toanspot 1ncubuled df 3PC immediaHy afker Recdpen-

8-1om OF BlGod collected n elood
auwtune RotHIe

aHnes (onvenhionad BoHle or Automated eeHe (BaCr/AlERI

 OATE
CELEBRO
PAG-

Isolahon
JHUDE
Cu

Qunnd AND
OBIOod AND Bone MaToDd
CEuIHae.tweek OF il hess)
conventonal GHI Baoth aga
Auhomaked Blod
BACTEC 0Y 4LERT
Cutue Susyen

stodlculktre (3-4 weet of itnecs.

Ethment eOHh Such asaselek n eth
TekgatHhio ncuke 6r0th
som NegHVe 8oth.

low sele&Hve medu m - Mac Conlrey ga

C+6ansulent NLE (olonies

Hrgbly selechye media DCA Agn

XLp agad
Wilson Bloi s Bismukh Sluphie
med um
- moHie omd 4oam-e Sann
Cullrre smeorr amd moH

910chemical ReaD

G catalate +ye
O Oxrda e -Ye oseue (-)
LOdole - ) ,
cikoate C+l)
T CUT
N MTtOde

except St Ph hS
TST k / 9ast)

lrde Ag9luhnahon [es t h e de00FY

pe
Confoon
 CELEBRO
DATE
PAGE-

ADHiboctics susciphbilty 1?S

on Multed Hinbn Agaer
It is done 6y clisk DfUnon Mehod
0Y MrC bated Methad (eg VITE

Sexubgir al Method CwWidal Tes

bweekness of lness Anhbodres cleeced Agains To TH , AH 8H
ankge
Ued semlooical te fo Diago00ns of
olde- Method widel
eneo Peves

Parcfple It is Aggluhonhon tes ühoss Hand 0? onHbodke

deeleced in semum against S:tuphf amd $ Poatsp[ 4andg3
by UJng AnkGen 'ol H.

ADHgen Uted.4Antigem orse uled

O oantfgen fo 6Tphf (TOD
n anngen foT S TYpbf CTH)
H anngen foa S:paatyphf A (AH
S'poeay e (BH)

00OteduG e
Sena
pt sesum diuhon.

m NCMo mA
Sali ne
A
690
 DATE

oF ditute terd Qespeti q Anh'en Suscepnon

ach set
70

). Added
TH, AH,BH
are
TO

Tet tube
incubkd in ho bath ko oveshirght al37o
al- 320c

esut

alubnabs n aprers as compac g5onulae cholky clump (dit ke paHex

withcleu

Cp agyluh noliov d appers as oge LoOe Fluh corttom

ruperohed SusDefisn
CoollyClump", c clears

neo pakahon

Nidal test ResulE SuggaHve oF

. T Ph,'
O Rke OF TO &TH Anhobod enmc fever d e

d+ s Pas ty phi A
a f TO 3 AH An bod

Of TO 9 H Anhbody -dL SParayph

B

Dcetinfethór
f only To Mobod DIE STUphj o% S. Pantyphj A 3B

Por TAB vacine

GRise in AU TH AH BH

AnHgen leHec hon Tes