Lymphatic System

Lab Interactive Session

1
 Di
oIn
oF
oIn
oN
oE

lym
GI
gland

Diffuse lymphoid tissue

2
ows indicate Primar
tic nodules in the of small
the ileum (Peyer’s Secon
s germinal
lymphoc

Paler reg
lymphoc
GC als
dendritic

Theref
tissue re

Mantle
ㅍ

of small

3
Palatine tonsil (two) in number on either side of the oral cavity

Crypt
lined by s
Epithelium epitheliu
•The epith
crypts
Crypts co
Lymphoid aggregate dead lym

•Mainly s

•Posterior
thick cap

4
Pharygeal Tonsil

Respiratory Epithelium

5
6
Hotspot for cancer metastasis, because more replication more 7
chance of cancer.
Epithelium Lymphoid aggregate

Mucus Glands
8
Lingual tonsil
 Lymphoid aggregate

pt
Epithelium

Mucus Glands
9
Lingual tonsil
Fetal THYMUS
Low magnification- thymus- H & E stain
Trabeculae -

Cortex

C
Medulla

Cortex:
- mainl
(thymo
reticula
H & E low magnification Medulla:
- mature T lymphocytes
10 &
 Trabeculae - run within to div

Capsule

Cortex

Medulla

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Fetal THYMUS
Low magnification- thymus- H & E stain

Thymic Corpuscles
Cortex

Medulla Trabecu

Thymic Corpuscles

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d supply: Enter through trabeculae into cortex and medulla. Characterized by continuous ca

T
c
c

•
t

•
e

d
a
a

•
T
a

13
 Blood Thymus Barrier
cortex
PILARY

thymocytes

ERC

Bloo
in th

T- lymphocytes

Th
Hassal’s corpuscle
mi
Ef
When BV entering Medulla, lose ERC medulla 14 Ly
covering
 Cortex

ERC

Medulla

e as lobules 15
 LYMPH NODE
Identify:
•Cortex
mphatic vessel – •Medulla
h through convex •Paracortex
•Capsule
•Hilum

16
Hilum - arteries and nerves enter :
 ?

cortex

medulla

edullary cords
ng

t when lymph
egion

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 Identify:
Cortex •Cortex
•Medulla
•Paracortex
•Subcapsular sinus
•Afferent lymphatic
•Lymphatic nodule/follicle

Medulla

18
Lymph node Silver Stain Identify the stain used

19
Paracortex (deep cortex) -High Endotheli
(HEV)

-allow for the transition of lymphocytes fro

blood stream to lymph tissue
-Excess lymph is reabsorbed

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SPLEEN H/E stain

Trabeculae

Trabecule
White Pulp

Red Pulp

Capsule
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H & E stain of spleen ( medium magnification)

Red

White Central Artery

Trabeculae

Marginal Zone

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H/E

ain

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24