(Tra

(H
(S
) (Tricyclic antidepressants
)(anticonvulsant

(B blockers
(calcium channel block
) (angiotensin converting enzyme inhibitors
):( Analgesics & Antipyretics
(paraceta
) (Salicy(
) (Nonsteroidal anti-inflammatory drugs
(

. :


) (synergism



%50 .

:(Major tranqui

) (Trifluoperazine stelazine ) (promazine, sparine (Largactil

(melle

(Non phenothiazines

(b )(haloperidol

)(

( Diphenyl butyl pipe )(Orap

(Dibe )(clozapine

(Minor tranqui

) (anticonvulsant

)partial

) (Ataxia .

:( Barbiturates

( )(Phenobarbital, Luminal

(Intermediat)(Amobarbital, Amytal

(s )(Secobarbital, Secona

(Ultra )(Thiopental, Pentothal

) (
.
.

) (Stertorous breathing
 ) (Albuminuria

)(endotracheal tube

.
.

:(chloral hyd

1869

:( Amph

.
 .

:(Theophylline and caffeine

.
) .( 85 30
60 - 40 )
)theophyline

) (left sided heart failure
) (status epilepticus
.(dysrhyt

.(hem

)(Tricyclic antidepressants

) (Selective Serotonin Reuptake Inhibitors

(imipramine HCL 1948 1958

195
.

(Ventricular) arrhythmias
.

. ) ) P H
. .

: 1988
) (prozac )( ) (dysyrel
) (arrhythmia
.

.
 :(anticonvuls

(c

(valp

) (status epilepticus
.

) :(pheny (

) (tremor ) (nystgmus )
) .(ataxia
.

: 50 /

) (propylene glycol .

(Fetal phenytoi %10 %30

) (clift lip ).(limb defect

:(ca

) (idiosyncrasy
)
.

:(valpro

) (nystagmus


.

:(B bloc

10 -3 5 .

:(calcium channel b

% 10 1
.

)(angiotensin converting enzyme inhibitors

,capoten ) ,(monopril ) (univasc )

) (angiotensin II ) ( angiotensin I

) (pectoris angina ) isosorbide dinitrate (isordil

.

)
) ( %30
.

%15 .% 30

1-2 (methyl /.

):( Analgesics & Antipyretics

.
.

:(parace

)) .panadol , tylenol, paramoletc

) ( dextropropoxyphene )
15-10/ 140/ .

) ( ) ( liver necrosis Atrophy

. Pancreatitis :
) (right subcostal margin
(live ) (jaundice

(N-acetyl cystein, muc %5 140 /

70 / 4/ .

) (parvolex 150 / 200 15

500 4 100 / 16 .
.

( diphenh .

) (Sa(:

) Aspocid, aspegic, askine,

15-10/ 150/ .

).(metabolic acidosis

) (.

.
 .

6 100/
).(Done nomogram

):(Nonsteroidal anti-inflammatory drugs

- (Ph )(Diflunisal

)(Sulindac

)(Indomethacin

)(Meclofenamate

)(Ibuprofen

. :

(metabo .

) (:
H1 ) )H2
) (H3

) (anticholinergic
.
.
 H1 20 ) (cimetidine

.2014 - .