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Number of Layers or Category Shape of Cells

Simple (Single layer of cells)  Squamous


 Cuboidal
 Columnar
Stratified (More than one layer of cells)  Squamous
o Nonkeratinized (moist)
o Keratinized
 Cuboidal (very rare)
 Columnar (very rare)
Pseudostratified (Modification of simple epithelium)  Columnar
Transitional (Modification of stratified epithelium)  Roughly cuboidal to columnar when not stretched and squamous-like when stretched

Structure Function Location


Simple Epithelium
Simple Squamous Epithelium Single layer of flat, often  Diffusion  Lining of blood vessels
hexagonal cells; the nuclei  Filtration and the heart
appear as bumps when viewed  Some secretion  Lymphatic vessels
in cross section because the  Some protection against  Alveoli of the lungs
cells are so flat friction  Portions of the kidney
tubules
 Lining of serous
membranes of body
cavities (Pleural,
Pericardial, Peritoneal)
Simple Cuboidal Epithelium Single layer of cube-shaped  Secretion and absorption  Kidney tubules
cells; some cells have microvilli by cells of the kidney  Glands and their ducts
(kidney tubules) or cilia (terminal tubules  Choroid plexuses of the
bronchioles of the lungs)  Secretion by cells of brain
glands and choroid  Lining of terminal
plexuses bronchioles of the lungs
 Movement of particles  Surfaces of the ovaries
embedded in mucus out
of the terminal
bronchioles by ciliated
cells
Simple Columnar Epithelium Single layer of tall, narrow cells;  Movement of particles  Glands and some ducts
some cells have cilia out of the bronchioles of  Bronchioles of the lungs
(bronchioles of the lungs; the lungs by ciliated cells  Auditory tubes
auditory tubes; uterine tubes,  Partially responsible for  Uterus
and uterus) or microvilli the movement of oocytes
(intestines) through the uterine tubes  Uterine tubes
by ciliated cells  Stomach
 Secretion by cells of the  Intestines
glands, the stomach, and  Gall bladder
the intestines  Bile ducts
 Absorption by cells of the  Ventricles of the brain
intestines
Pseudostratified Columnar Single layer of cells; some cells  Synthesize and secrete  Lining of nasal cavity
Epithelium are tall and thin and reach the mucus onto the free  Nasal sinuses
free surface, and others do not; surface and move mucus  Auditory tubes
the nuclei of these cells are at (or fluid) that contains  Pharynx
different levels and appear foreign particles over the  Trachea
stratified; the cells are almost surface of the free  Bronchi of the lungs
always ciliated and are surface and from
associated with goblet cells that passages
secret mucus onto the free
surface
Stratified Epithelium
Stratified Squamous Epithelium Several layers of cells that are  Protects against abrasion  Keratinized – outer layer
cuboidal in the basal layer and  Forms a barrier against of the skin
progressively flattened toward infection  Nonkeratinized – mouth,
the surface; the epithelium can  Reduces loss of water throat, larynx,
be nonkeratinized (moist) or from the body esophagus, anus, vagina,
keratinized; in nonkeratinized inferior urethra, and
stratified squamous epithelium, corneas
the surface cells retain a nucleus
and cytoplasm; in keratinized
stratified epithelium, the
cytoplasm of cells at the surface
is replaced by a protein called
keratin, and the cells are dead
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