Scribd Logo
Upload

Welcome to Scribd!

  • Alternative Pathway

    Uploaded by

    Miki Abera
    7 views1 page
    The document summarizes the alternative complement pathway. It starts with C3b binding to Factor B to form the C3bB complex, which is stabilized by properdin to function as the C3 convertase that generates more C3b. This alternative pathway can be activated by substances like lipopolysaccharide from gram-negative bacteria, lipoteichoic acid from gram-positive bacteria, zymosan from yeast cell walls, cobra venom, or surface components of some parasites.

    Original Description:

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    The document summarizes the alternative complement pathway. It starts with C3b binding to Factor B to form the C3bB complex, which is stabilized by properdin to function as the C3 convertase that generates more C3b. This alternative pathway can be activated by substances like lipopolysaccharide from gram-negative bacteria, lipoteichoic acid from gram-positive bacteria, zymosan from yeast cell walls, cobra venom, or surface components of some parasites.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    7 views1 page

    Alternative Pathway

    Uploaded by

    Miki Abera
    The document summarizes the alternative complement pathway. It starts with C3b binding to Factor B to form the C3bB complex, which is stabilized by properdin to function as the C3 convertase that generates more C3b. This alternative pathway can be activated by substances like lipopolysaccharide from gram-negative bacteria, lipoteichoic acid from gram-positive bacteria, zymosan from yeast cell walls, cobra venom, or surface components of some parasites.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 1

    Alternate Pathway

    mmmm
    starting Point
    ↳ Csb + Factor B→C3bB
    actor D

    Ba + Bb
    [ neutrophils foµ ☆C3b
    chemotactic

    C3bBb¥s convertase]

    1 I
    stabilized by Properdin
    csbinhibiedby
    ↓ ¥ £3b
    ↑
    Factor Hits generate more Csb
    C3bnBb↑
    ••

    ↳Eboonvetase ↑
    •• •

    ~
    C5a+C⑤↑
    t.P-sprinitivedelnsesysten-ativatdby3.es membrane attack
    1) lipopolysaccharide→ G-Ve bacteria ☒ pathway initiated,

    2) kiohoicaa'd >
    Give bacteria
    N*
    3) Zymosan > yeast all walls

    4) Cobra Venom

    5) Surface component of some parasites

    You might also like