:

Enaoeba histolytica -
Giardia lamblia -
Cryptosporidium parvum-
Trypanosoma brucei -
Trypanosoma cruzi- Changs-
Leishmania spp. -
Balantidinium coli-
Trichomonas vaginalis-

 Enaoeba histolytica

Enaoeba

histolytica

-
-
-
:


GIT



:

, -
-

 Enaoeba histolytica

 Enaoeba histolytica

 :


< 40%

:
1. - :
- emetin, dihidro emetin
- metronidazol
- chloroquine

2. :
- parmomycin
8- - iodoquinol
- carbarsone, diloxanide

furazolidon, metronidazol
quinacrine
Giardia lamblia

Giardia lamblia

Trypanosoma

(),
, , (nifurtimox)

1. Metronidazole

e

:

(+) (Clostridium spp) (-) ( Bacteroides spp.).

, ,


Metronidazole

:
-
DNA
:
,


2-
:

-
- ( , )
500mg

2 g

:
,, , .
( , )

2. 8-Hydroxy quinoline - Oxine, quinophenol oxyquinoline

:


, , 1:3000

7 8-
= Iodoquinol

, .

3.Emetine Dehydroemetine

:



i.m pH=3.5
1-2
:

-
,
,

:
GIT ()
( )
( )

4. Pentamidine Isethionate

:
Pneumocistis carnii,
AIDS

i.v i.m
- AIDS (+)

:
( )
( )

5. Atovaquinone

, ubiquinone 6

ubiquinone 6 -



, ,
95% , 99%
GIT

6.Nifurtimox
5-
T.cruzi
, first pass
2-4
:

, ,
, ,

7.Benznidazole

( )
:
,

8.Melarsoprol
:
2,3
-1 (BAL)
T
CNS
T.gambinese. T.rhodesinese
3- 5-
.

8. Dimercaptol - 2,3 -1 (BAL)

A .
Ar, An, Hg, Au.
SH
SH .
:

5-10%

9. Suramin Sodium

6 Na


( )

 - ,
,

, :
,
Platyhelminiti
Nemathelminti

CNS
:

,
(.)

1. Piperazine -
Enterobius Oxyuris Ascaris lumbricoides

CNS

2. Diethyl carbamazepine
(, )
:

3. Pyrantel

Pamoate

4. Albendazole, Thiabendazole, Mebendazole

:
-
-

up take

:


e

Thiabendazole

Mebendazole

Albendazole

5. Niclosamide

() 1-2

6. Bithionol




Fasciola hepatica,

7. Oxaminiquine
:
DNA, RNA
6-
6-
,

Sarcoptes
scabei ()

(Pediculosis corporis, capitis et pubis)

1. Benzyl Benzoate -
-
( )

25%

2. Lindane
:

(; ; ; ; )
( 10-13%)
:

3. Crotamiton
10%
scabies

4. Permethrin
4
1( R )-trans 1(R)-cis

(60-40%)


1%