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e ,

2013

, , 2013

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ISBN 978-954-9318-26-5

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8; . 0887005092; e-mail: ditcheli@abv.bg

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.

1. , . . ., . ., 1988.
2. , . . ., . ., 1992, 589 .
3. . . .- . . , , 1994.
4. , . . , , 2006, 460 .
5. , . (- ). ,
-, 2007, 375 .
6. , . . ., . ., 2002, 813 .
7. . . .. . ., 2008.
8. , . . . ,
, 2009, 296 .
9. , . . . , 2002.
10. , . . . ., , 2005, 106 .
11. . . . . . . . .,
. ., 1987.
12. , . . ., ,
2012, 208 .
13. , . . ., 2002.
14. B o r g h i , L. et al. Comparison of two diets for the prevention of recurrent stones in idiopathic
hypercalciuria. N. Engl. J. Med., 346, 2002, 2, 77-84.
15. B o u l w a r e , L. E. et al . Identification and referral of patients with progressive CKD: a national
study. Am. J. Kidney Dis., 48, 2006, 192.
16. C a m e r o n , J. S. The Long-Term Outcome of Glomerular Diseases. In: Schrier RW, Gottschalk
CW, ed. Diseases of the Kidney. 6th ed. Little, Brown & Company: Boston, Mass; 1997, 1919.
17. C h a n d h o k e , P. S. Evaluation of the recurrent stone former. Urol. Clin. North. Am., 34,
2007, 3, 315-322.
18. C o o p e r , J. T., G. M. Stack et T. P. Cooper. Intensive medical management of ureteral calculi.
Urology, 56, 2000, 4, 575-578.

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19. Coresh, J., M. Walser et S. Hill. Survival on dialysis among chronic renal failure patients treated
with a supplemented low-protein diet before dialysis. J. Am. Soc. Nephrol., 6, 1995, 5, 1379-
1385.
20. E v a n , A. P. et al. Mechanism of formation of human calcium oxalate renal stones on Randall's
plaque. Anat. Rec. (Hoboken), 290, 2007, 10, 1315-1323.
21. G u p t a , K. et al. International clinical practice guidelines for the treatment of acute
uncomplicated cystitis and pyelonephritis in women: A 2010 update by the Infectious Diseases
Society of America and the European Society for Microbiology and Infectious Diseases. Clin.
Infect. Dis., 52, 2011, 5, 103-120.
22. J a f a r , T. H. et al. Proteinuria as a modifiable risk factor for the progression of non-diabetic
renal disease. Kidney Int., 60, 2001, 1131-1140.
23. K a w a s a k i , Y. Mechanism of onset and exacerbation of chronic glomerulonephritis and its
treatment. Pediatr Int., 53, 2011, 6, 795-806.
24. K / D O Q I clinical practice guidelines for chronic kidney disease: evaluation, classification, and
stratification. Am. J. Kidney Dis., 39, 2002, (2 Suppl. 1), 1-266.
25. K u y p e r s , D. Skin problems in chronic kidney disease. Nat. Clin. Pract. Nephrol., 2009, 5,
157-170.
26. L e z i n , St. M., R. Hofmann et M. L. Stoller. Pyonephrosis: diagnosis and treatment. Br. J.
Urol., 70, 1992, 4, 360-363.
27. L e v y M. et J. Berger. Worldwide perspective of IgA nephropathy. Am. J. Kidney Dis., 12,
1988, 5, 340-347.
28. L u o , C. et al. Clinicopathological features and prognosis of Chinese patients with acute post-
streptococcal glomerulonephritis. Nephrology (Carlton), 15, 2010, 6, 625-631.
29. M a n g r u m , A. J. et G. L. Bakris. Angiotensin-converting enzyme inhibitors and angiotensin
receptor blockers in chronic renal disease: safety issues. Semin. Nephrol., 24, 2004, 2, 168-
175.
30. N a s r , S. H. et al. Postinfectious glomerulonephritis in the elderly. J. Am. Soc. Nephrol., 22,
2011, 1, 187-195.
31. N i c o l l e , L. et al. Pharmacokinetics/pharmacodynamics of levofloxacin 750 mg once daily in
young women with acute uncomplicated pyelonephritis. Int. J. Antimicrob Agents. 31, 2008,
3, 287-289.
32. P e t e r s o n , J. et al. A double-blind, randomized comparison of levofloxacin 750 mg once-daily for
five days with ciprofloxacin 400/500 mg twice-daily for 10 days for the treatment of complicated
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54

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57
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61
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63
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66
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67
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69
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70
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71
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72
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(Anaemia aplastica)

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73
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74
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75
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76
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77
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78
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79
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.

81
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82
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,

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83
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84
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.

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85
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86
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87
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COPP Ciclophosphamid

V . ABVD Adriamycin,
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, Bleomycin,
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6 2 .

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88

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89
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: ,
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. ,
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,
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91
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.

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92
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93
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:
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95
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96
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180 min.
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97
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.
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: .
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98
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1 amp. i.v. , 3
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.

: .
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,
.

99
( )

(Thrombocytopenia essentialis, Morbus Werlhof)

- .
.

: -

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: .

, - 1-4 -
. ,
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, ( -
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.

.
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. , -
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, , ,
. .

: , -
, , ,
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.

: (), -
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, ), (, .). -
.

100
( -)

(Capillarotoxicosis, Morbus Shonlein-Henoch)

- . -
- .

: -
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,
. ,

.

: , ,
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. -
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.

-
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.

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.

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: ,
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.

101

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5.
;

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;

7. , -
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;

8.
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9. , -
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,
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102
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:

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;

( , , )
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103
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10 , (, ,
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, ;

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3-4
: , , -
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24 h;

13. -
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104
, , , -
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;

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;

3
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14. -
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;

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, -

105
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30-40 /min.

,
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;


24 h : ,
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, , -
1 min, -
;

15. -
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16.
:

-
;


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.

106
17.
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;

;
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:

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;
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107

;

20.
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, , , ,
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;


();

21. -
:


( , .);

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108

1. , . . ., . ., 1992, 589 .
2. . . . - . . , , 1994.
3. , . . , , 2006, 460 .
4. , . (- ). ,
-, 2007, 375 .
5. , . . ., . ., 2002, 813 .
6. . . . . . ., 2008.
7. , . . . , -
, 2009, 296 .
8. , . . . ., 2002.
9. , . . . ., , 2005, 106 .
10. , . . ., 2002.
11. A l l e y n e , M., M. K. Horne, J. L. Miller. Individualized treatment for iron-deficiency anemia in
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111

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118
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119
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120
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121
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122
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123

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124
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126

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127
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128
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129
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. , , ,
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.

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131

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132
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, . -

134
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.

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.

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.

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135
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.

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137
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.

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.

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.

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138
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.

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.

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, . -
.

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.

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.

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139
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.

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(Dostinex).

-
,
.

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140
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.

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.

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,
.

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.

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141
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.

142
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. (-
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, ,
, , . 5-
6 .

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-

(Sopolcort) 100-200 mg (Urbason) 20-40 mg, -
5% 500 ml + 100 mg 20 mg
. ,
3-4 l/24 h 5%
, .
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,
, , .

. - -

.
.

143

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.
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, -
.

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144
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. -
. -
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.

, , , .

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. -
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, .


, ,
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.
.
,
.
,
.
.
, ,
. -
.

145
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,
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146
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) .

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; .

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. ( 7 h, 12 h, 18 h), (7
h, 12 h, 15 h, 18 h), (7 h, 12 h, 15 h, 18 h, 21 h) ..

4. () 75 g
, 200 ml 5 min. -
0 min ( ,
), 60 min, 120 min 180 min. ,
.

5. -
, -, .

. -
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/, , -
- .

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: () , -
, -
, .
-
.

: 1 ( 1, -
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-
, , , .

147
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, , -
. , -
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. , -
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,
, ,
.

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,
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, , , -
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.

4.
, ,
.

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148
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,
, -, -
.

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.
.
, 1,
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.
,
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, , -
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, .

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1. , . . ., . ., 1992, 589 .
2. , . .
., -2001, 2009, 143.
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, -, 2007, 375 .
6. , ., . . . ., IP Bulgaria, 2007,
349-368.
7. , . . ., . ., 2002, 813 .
8. , . (.). . ., , 2000, 1100 .
9. . . . . ..,
, . , 2008, 432.
10. , . . . ,
, 2009, 296 .
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12. , . . . ., , 2005, 106 .
13. . . . . . . . .,
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