ALL ABOUT VIROLOGY 2 (pg 384 – 399)##BY : RAJA PARDOMUAN HARAHAP

Similar respiratory symptoms can be caused by several different viruses.

Bronchiolitis may be caused by two viruses. What are they?
1
Respiratory syncytial virus (RSV), Parainfluenza virus

2
One virus may cause different symptoms in different people. Mention two diseases or
symptoms caused by Influenza virus.
Mild upper respiratory tract infection, pneumonia

3
Name two viruses that initiate infection in the lung and can cause pneumonia but
generally cause systemic infections, resulting in an exanthem (rash).
Measles and Varicella-zoster viruses

Pleurodynia is associated with what virus?

4
Coxsackievirus B

What virus associated with infectious mononucleosis?

5
Epstein-Barr virus (EBV)

Tonsillitis with exudative membranes and sore throat without vesicular lesions are
characteristics of two viral infections. What are they?
6
Epstein-Barr virus and Adenovirus

Gingivostomatitis and herpes labialis are associated with what virus?

7
Herpes simplex virus 1

Name two viruses associated with tonsil infection with vesicular lesions.
8
Herpes simplex virus and coxsackievirus A

Koplik spots are vesicular lesion on the buccal mucosa which associated with what
virus?
9
Measles virus

Name two viruses that cause common cold.

10
Rhinovirus, Coronavirus

Echovirus is abbreviation of what?

11
Enteric cytopathic human orphan virus

Inflammatory response to viral infection cause the trachea to narrow below the
vocal cords, the resulting what condition in adults?
12
LARYNGITIS, vocal cord = subglottic area

In croup, the narrowing of trachea causes loss of voice, a hoarse, barking cough,
risk for a blocked airway and choking. What is the causative agent of croup?
13
Parainfluenza virus 1, 2, 3

What is the causative agent of life-threatening pneumonia or bronchiolitis in

infants younger than 6 months?
14
Parainfluenza 3 virus, Respiratory syncytial virus

Which bacteria infection becomes raised caused by influenza virus infection?

15
Staphylococcus aureus, Streptococcus

16
Name viruses that cause gastrointestinal disease, together in adults, children, and
infants.
Norwalk virus
Calicivirus
Astrovirus
Rotavirus A and B (China)
Reovirus

17
Name two most common cause of viral pharyngitis.
Adenovirus, Coxsackievirus A

Name two most common cause of viral bronchiolitis.

18
Respiratory syncytial virus in infants
Parainfluenza virus 3 in infants and children

Name three most common cause of viral pneumonia.

19
Respiratory syncytial virus in infants
Parainfluenza virus in infants
Influenza virus

20
Arthritis and other inflammatory disease may result from what phenomenon of immune
response?
Cytokine storm and immune hypersensitivity responses : immune complexes

21
Which is not common viral disease?##1. Common cold#2. Gastroenteritis#3. Flulike
syndromes#4. Influenza#5. Meningitis
5

22
Where is the most common site of viral infection and disease?##1. Oropharynx and
respiratory tract#2. Gastrointestinal tract#3. Central nervous system#4.
Genitourinary tract#5. Musculoskeletal manifestations
1

23
Which is not the virus that establishes primary infection of the oropharynx or
respiratory tract and then progress to the other sites?##1. Mumps virus#2. Rubella
virus#3. Poliovirus#4. Enteroviruses#5. Human herpesviruses
3

24
Which condition that compromise the ciliated and mucoepithelial barriers to
infection lead to increase the risk of serious disease?##1. Alcoholism#2. Drug
abusing#3. Drug addiction#4. Smoking and cystic fibrosis#5. Lung transplantation
4

25
Which is not the characteristic of coxsackievirus A infections?##1. Oral vesicular
lesions#2. Fever#3. Maculopapular centrifugal rash#4. Pharyngitis
3
THIS IS HERPANGINA AND HAND-FOOT AND MOUTH DISEASE CAUSED BY COXSACKIEVIRUS A16

26
Which is not causative agent of pneumonia?##1. Adenovirus#2. Paramyxovirus#3.
Varicella-zoster virus in adult#4. Epstein-Barr virus in infant
4

27
Which is not the causative agent of gastrointestinal infection in infants?##1.
Rotavirus A#2. Norwalk virus#3. Adenovirus 40, 41#4. Coxsackievirus A24
2

28
Which is the causative agent of gastrointestinal infection in adults?##1. Rotavirus
A#2. Norwalk virus#3. Adenovirus 40, 41#4. Coxsackievirus A24
2

29
Naked capsid viruses are associated most commonly with what infection?##1.
Gastrointestinal infection#2. Oropharynx and respiratory tract infections#3.
Hematologic infection#4. Arthropod-borne infection
1

30
Which virus can induces skin disease, results from infection through the mucosa or
small cuts or abrasions in the skin?##1. Herpes simplex virus (HSV)#2. Varicella-
zoster virus (VZV)#3. Parvovirus B19#4. Smallpox
1

31
Which virus can induces skin disease, results from inflammatory response mounted
against viral antigens?##1. Herpes simplex virus (HSV)#2. Varicella-zoster virus
(VZV)#3. Parvovirus B19#4. Smallpox
3

32
Which is not the characteristic of most hemorrhagic fever virus?##1. Establishes
viremia#2. Infect endothelial lining of vasculature#3. Rupture of blood vessels#4.
Hemorrhagic rash: petechiae, ecchymoses#5. internal bleeding, shock, loss of
electrolytes#6. Leukopenia, rigor, hyperthermia, hypotension
6

33
Which is not the causative agent of pink eye conjunctivitis?##1. Measles virus#2.
Rubella virus#3. Adenovirus 8, 19a, 37#4. Adenovirus 3, 4a, 7
3

34
Which is the causative agent of keratoconjunctivitis?##1. Measles virus#2. Rubella
virus#3. Adenovirus 8, 19a, 37#4. Adenovirus 3, 4a, 7
4
35
Which is not the causative agent of keratoconjunctivitis?##1. Measles virus#2.
Herpes simplex virus#3. Adenovirus 8, 19a, 37#4. Varicella-zoster virus
1

36
Which is the virus that has kidney as target organ?##1. Coxsackievirus B#2.
Cytomegalovirus#3. Epstein-Barr virus#4. Coxsackievirus A24#5. Mumps virus
2

37
Which is not the virus that has glands as the target organ?##1. Cytomegalovirus#2.
Mumps virus#3. Coxsackievirus B#4. Yellow fever virus
4

38
Which is not the virus that causes hepatitis in the neonate or immunocompromised
person?##1. Cytomegalovirus#2. Herpes simplex virus#3. Varicella-zoster virus#4.
Enterovirus 70#5. Rubella virus
4

39
What is the causative agent of pleurodynia?##1. Coxsackievirus B#2. Coxsackievirus
A#3. Cytomegalovirus#4. Epstein-Barr virus#5. Rubella virus
1

40
What is the causative agent of Boston exanthem?##1. Echovirus 16#2. Human
parvovirus B19#3. Human herpesvirus 6#4. Epstein-Barr virus#5. Measles virus
1

Norwalk virus, calicivirus, astrovirus, adenovirus, reovirus, and rotavirus infect

what organ?
41
SMALL INTESTINE NOT COLON

Name two viruses that cause infantile gastroenteritis.

42
Rotavirus A, adenovirus 40, 41

43
Name two viruses that cause outbreaks of gastroenteritis affecting older children
and adults due to contaminated food or water source.
Norwalk virus, calicivirus

44
Name the virus that is spread by fecal-oral route, but usually cause only mild or
no gastrointestinal symptoms.
Enterovirus

Name the virus that generally causes warts by stimulating the growth of skin cells.
45
Human papillomavirus (HPV)

Name the virus that causes wart-like growths (nodules) by stimulating the growth of
skin cells.
46
Molluscum contagiosum virus
47
What is the etiologic agent of roseola infantum/exanthem subitum?
Human herpes virus 6

What is genus of the etiologic agent of fifth disease/erythema infectiosum?

48
Parvovirus B19 – genus Erythrovirus – family Parvoviridae

Name viruses that have arthritis as consequence.

49
Togaviruses (Chikungunya virus, rubella virus
Parvovirus B19
Flavivirus (dengue virus, hepatitis C virus)
HBV
HIV
Human T-cell lymphotropic virus 1 (HTLV-1)

Which adenovirus serotypes that cause epidemic keratoconjunctivitis?

50
Adenovirus 8, 9, 11, 19a, 35, 37

Name two virus that cause acute hemorrhagic conjunctivitis.

51
Enterovirus 70, Coxsackievirus A24

Cataracts are classic features of babies born with what syndrome?

52
Congenital rubella syndrome

Chorioretinitis is associated with infection in newborns (congenital) by what

virus?
53
Cytomegalovirus (CMV)

54
Chorioretinitis is associated with infection in immunosuppressed people (AIDS) by
what virus?
Cytomegalovirus (CMV)

Name a virus that induce infection in the heart.

55
Coxsackievirus B

56
Which virus that causes oral and genital lesions?##1. Varicella-zoster virus#2.
Herpes simplex virus#3. Coxsackievirus A#4. Human papillomavirus#5. Echovirus 16
2

57
Which is not included in cytopathologic effects caused by viral infection?##1.
Intracytoplasmic projection#2. Cell morphology#3. Cell lysis#4. Vacuolation#5.
Syncytia#6. Inclusion bodies
1

58
Which is not the laboratory procedures for diagnosing viral infections?##1. Light
microscopy#2. Cytologic examination#3. Virus isolation and growth#4. Detection of
viral proteins (antigens and enzymes)#5. Serology
1. Harusnya electron microscopy

59
In what family is the causative agent of California encephalitis?##1.
Bunyaviridae#2. Flaviviridae#3. Togaviridae#4. Arenaviridae#5. Filoviridae
1

60
What is the vector of yellow fever?##1. Culex mosquito#2. Aedes mosquito#3. Tick#4.
Louse#5. Chigger mites
2

61
What is the etiologic agent of progressive multifocal leukoencephalopathy?##1. BK
virus#2. California encephalitis virus#3. Human papillomavirus#4. John-Cunningham
virus#5. Simian virus 40
4

62
Which is the virus that is less associated with paralysis condition?##1.
Poliovirus#2. Enterovirus 70#3. Enterovirus 71#4. Coxsackievirus A7#5. Chikungunya
virus
5

63
Which virus is associated with tropical spastic paraparesis?##1. Measles virus#2.
HIV#3. John-Cunningham virus#4. HTLV-1
4

64
Which is the causative agent of spongiform encephalopaties (kuru, GSS, CJD)?##1. JC
virus#2. BK virus#3. Lassa virus#4. Prion#5. Lymphocytic choriomeningitis virus
4

65
Which virus is associated with subacute sclerosing panencephalitis?##1. HTLV-1#2.
Measles virus#3. HIV#4. JC virus#5. BK virus
2

66
What is the name of this appearance and the causative agent?
Syncytium formation (multinucleated giant cell) by measles virus
Disease = giant cell pneumonia in immunocompromised patients

67
Viruses are best transported stored on ice and in special media that contain
antibiotics and proteins such as what?##1. Immunoglobulin#2. Serum albumin and
gelatin#3. Amino acids#4. Fatty acids#5. Numerous glycoprotein by products
2

68
A focal encephalitis with a temporal lobe localization preceded by headaches and
disorientation suggests what viral infection?#1. Enterovirus#2. Japanese B
encephalitis virus#3. Cytomegalovirus#4. West-Nile encephalitis virus#5. Herpes
simplex virus
5

69
Which is less commonly the clinical specimen we used to diagnose enterovirus
infection?##1. Stool#2. Blood#3. Cerebrospinal fluid#4. Throat swab
2

70
What is the name of this method?##1. Neutralization test assay#2. Hemagglutination
reaction#3. Serotyping#4. Western blot analysis
2

71
What two specimens could we use for diagnosing meningitis symptoms during the
summer caused by arboviruses?
Cerebrospinal fluid, blood

72
What is the name of this appearance and the causative agent?
Eosinophilic Cowdry type A intranuclear inclusion body
Herpes simplex virus
Organ = LIVER

73
What is the name of this appearance and the causative agent?
Negri bodies
Rabies virus from family Rhabdoviridae
Organ = BRAIN

74
What is the name of this process and the causative agent?
Hemadsorption of erythrocytes
Influenza viruses, mumps virus, parainfluenza virus, togaviruses

75
What is the characteristic name of papillomavirus-infected keratinocytes with
enlarge and clear halos around shrunken nuclei?
Koilocyte

76
What virus causes diarrhea by enterotoxin?
Rotavirus

77
What is the best temperature for keeping the virus for more than one year?
1960C or 3200F

78
Name types of human cells where JC virus causes latent and chronic infection.
Monocyte, Lymphocyte, Oligodendrocyte, Astrocyte

79
What protein from Rotavirus that prevent water absorption and increases water
secretion?
NSP4 protein

80
What is the name of this process?
Koilocytosis
Papanicolaou stain of exfoliated cervicovaginal squamous epithelial cells, showing
the perinuclear cytoplasmic vacuolization termed koilocytosis (vacuolated
cytoplasm), which is characteristic of human papillomavirus infection
81
What is the name of this appearance and the causative agent?
Atypical Downey T-cell
Epstein-Barr virus

82
What is the name of this appearance and the causative agent?
Owl’s eye = basophilic nuclear inclusion body
Cytomegalovirus

83
What is the name of this appearance and the causative agent?
Molluscum bodies
Molluscum contagiosum virus

84
What is the name of this appearance and the causative agent?
Slapped-cheek appearance of erythema infectiosum = fifth disease
Parvovirus B19

85
What is the family of this virus?
Filoviridae