Professional Documents
Culture Documents
1
Published online www.wanfangdate.com.cn doi:10. 3969 / j.issn.1006-7108. 2020. 01. 027 135
·综述·
骨质疏松症的中医病因病机认识与治疗进展
梁伟乔1 钟诚1 李宇明2∗
1.暨南大学附属江门中医院,广东 江门 529000
2.中山大学附属江门医院,广东 江门 529000
Abstract: The incidence of osteoporosis in China is increasing year by year. The situation of prevention and treatment of
osteoporosis is getting more severe. At present, there are still some problems in the prevention and treatment of osteoporosis with
Western medicine alone, such as adverse reactions and imprecise curative effect. This provides an urgent requirement for finding
satisfactory treatment method in clinical practice. Chinese medicine has a unique opinion on etiology and pathogenesis of
osteoporosis, and has many kinds of treatment for osteoporosis. This paper summarizes the research of osteoporosis in Chinese
medicine, and provides theoretic and clinical evidence for osteoporosis treatment with TCM.
Key words: osteoporosis; Chinese medicine; treatment
治疗骨质疏松症提供了很好的指导依据,使用中医 [6] Klop C, Welsing PM, Elders PJ, et al. Long-term persistence
with antiosteoporosis drugs after fracture [ J ] . Osteoporos Int,
药治疗 OP 有着很好的发展前景。 其中中药、针灸
2015,26:1831-1840.
方面的研究贡献尤为突出,目前对单味中药治疗 OP
[7] Wang DH, Lin YF, Chen L, et al. Guided bone regeneration
的研究已证明其治疗机制是多靶点性的、多通路的、 using a bone tissue engineering complex consisting of a poly-dl-
全身性的,充分突显了中药的独特优势,这也与骨质 lactide membrane and bone mesenchymal stem cells [ J ] .
疏松症的多病因性相契合,表明运用现代药理方法 Oncotarget,2018,9(23) :16380-16388.
研究提取中药中治疗 OP 的成分无疑是一条充满光 [8] Qin SY, Zhou W, Liu SY, et al. Icariin stimulates the
proliferation of rat bone mesenchymal stem cells via ERK and p38
明的道路,且针灸、推拿、理疗等纯绿色方法又弥补
MAPK signaling [ J ] . Int J Clin Exp Med, 2015, 8 ( 5 ) :
了单纯中药应用的不足,效果好,副作用少。 在取得 7125-7133.
成绩的同时也存在着不足,推拿理疗等方法的实验 [9] Liu H, Xiong Y, Zhu X, et al. Icariin improves osteoporosis,
数据不足,缺乏分子水平上的机制研究,临床研究纳 inhibits the expression of PPARγ, C / EBPα, FABP4 mRNA,
万方数据